Studies on the stability and protein adsorption characteristics of heparinized polymer surfaces by radioisotope labeling techniques

1967 ◽  
Vol 1 (2) ◽  
pp. 239-251 ◽  
Author(s):  
R. D. Falb ◽  
M. T. Takahashi ◽  
G. A. Grode ◽  
R. I. Leininger
2000 ◽  
Vol 192-195 ◽  
pp. 889-892 ◽  
Author(s):  
S. Takashima ◽  
S. Takemoto ◽  
Kanji Tsuru ◽  
Satoshi Hayakawa ◽  
Akiyoshi Osaka

Langmuir ◽  
2008 ◽  
Vol 24 (18) ◽  
pp. 10253-10258 ◽  
Author(s):  
Joanna Zemła ◽  
Małgorzata Lekka ◽  
Joanna Wiltowska-Zuber ◽  
Andrzej Budkowski ◽  
Jakub Rysz ◽  
...  

2007 ◽  
Vol 58 (2) ◽  
pp. 98-104 ◽  
Author(s):  
Kazuhiko Kandori ◽  
Shintaro Tsuyama ◽  
Hidekazu Tanaka ◽  
Tatsuo Ishikawa

1991 ◽  
Vol 237 ◽  
Author(s):  
Kevin L. Prime ◽  
George M. Whttesides

ABSTRACTSelf-assembled monolayers (SAMs) of functionalized alkanethiolates on gold are a well-characterized system for studying the interfacial properties of organic materials. We have used SAMs as models for the surfaces of organic polymers and used mem to study the adsorption of proteins onto organic materials. We have formed SAMs from mixtures of alkanethiols in which one alkanethiol is hydrophobic and the other is terminated by a short (2 ≤ n ≤ 17) oligomer of poly(ethylene oxide). These “mixed” SAMs effectively resist the adsorption of fibrinogen from moderately concentrated (1 mg/mL) solutions. Protein adsorption begins when < 5% of the accessible area of the surface consists of hydrophobic groups. These findings suggest that real protein-resistant monolayers must present an almost defect-free surface of oligo(ethylene oxide) groups in order to eliminate adsorption.


Langmuir ◽  
2008 ◽  
Vol 24 (18) ◽  
pp. 10340-10344 ◽  
Author(s):  
Koji Futamura ◽  
Ryosuke Matsuno ◽  
Tomohiro Konno ◽  
Madoka Takai ◽  
Kazuhiko Ishihara

1997 ◽  
Vol 8 (2) ◽  
pp. 91-102 ◽  
Author(s):  
Yasuhiko Iwasaki ◽  
Akiko Fujke ◽  
Kimio Kurita ◽  
Kazuhiko Ishihara ◽  
Nobuo Nakabayashi

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