scholarly journals New prognostic factor for hepatitis B virus‐related decompensated cirrhosis: Ratio of monocytes to HDL‐cholesterol

Author(s):  
Qianxia Wu ◽  
Weilin Mao
2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Ming Cai ◽  
Zhong Han ◽  
Xia He ◽  
JinFei Zhang

Background. We sought to determine the prognostic value of prothrombin time-international normalized ratio to albumin ratio (PTAR) in patients with hepatitis B virus-associated decompensated cirrhosis (HBV-DeCi). Methods. The study enrolled 166 HBV-DeCi patients. Multivariate regression analysis was performed to identify predictors associated with mortality. Results. Among the 166 HBV-DeCi patients, 27 (16.3%) had died by 30 days after admission. PTAR was markedly increased in nonsurvivors compared with survivors, and had a significant positive correlation with disease severity. Multivariate analysis identified PTAR as an effective independent predictor for mortality in HBV-DeCi patients. Conclusions. High PTAR was associated with poor outcomes and can act as a novel prognostic predictor for mortality in HBV-DeCi patients.


Medicine ◽  
2017 ◽  
Vol 96 (25) ◽  
pp. e7133 ◽  
Author(s):  
Tae Yang Jung ◽  
Dae Won Jun ◽  
Kang Nyeong Lee ◽  
Hang Lak Lee ◽  
Oh Young Lee ◽  
...  

Gut and Liver ◽  
2017 ◽  
Vol 11 (6) ◽  
pp. 828-834 ◽  
Author(s):  
Jihye Park ◽  
Kyu Sik Jung ◽  
Hye Won Lee ◽  
Beom Kyung Kim ◽  
Seung Up Kim ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Tian-Yu Zhao ◽  
Qing-Wei Cong ◽  
Fang Liu ◽  
Li-Ying Yao ◽  
Ying Zhu

Background: Mean corpuscular volume (MCV) is major used as an indicator for the differential diagnosis of anemia. Macrocytic anemia in decompensated cirrhosis is common. However, the relationship between macrocytic anemia and decompensated hepatitis B virus (HBV) associated cirrhosis has not been fully addressed.Methods: In this cross-sectional study, a total of 457 patients diagnosed decompensated HBV associated cirrhosis who met all inclusion criteria from 2011 to 2018 were analyzed. Association between macrocytic anemia and the liver damaged (Model for End Stage Liver Disease (MELD) score) were examined using multiple logistic regression analyses and identified using smooth curve fitting.Results: Compared with normocytic anemia, MCV and MELD are significantly positively correlated in macrocytic anemia (p < 0.001). A non-linear relationship of MCV and MELD association was found though the piecewise linear spline models in patients with decompensated HBV associated cirrhosis. MCV positive correlated with MELD when the MCV was greater than 98.2 fl (regression coefficient = 0.008, 95% CI 0.1, 0.4).Conclusion: Macrocytic anemia may be a reliable predictor for mortality because it is closely related to the degree of liver damage in patients with decompensated HBV associated cirrhosis.


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