scholarly journals Intravascular large B‐cell lymphoma in random deep skin biopsies as a cause of pyrexia of unknown origin

eJHaem ◽  
2021 ◽  
Author(s):  
Kirollos Salah Kamel ◽  
May Chiu ◽  
Penelope Anne Wright
2017 ◽  
Vol 18 ◽  
pp. 482-486 ◽  
Author(s):  
Horacio di Fonzo ◽  
Damian Contardo ◽  
Diego Carrozza ◽  
Paola Finocchietto ◽  
Adriana Rojano Crisson ◽  
...  

2021 ◽  
Vol 2 (12) ◽  
pp. e0204
Author(s):  
Gilbert Wilfred ◽  
Hamizah Shukri ◽  
Ngee Siang Lau ◽  
Alina Md Fauzi ◽  
Sen Mui Tan ◽  
...  

2016 ◽  
Vol 91 (11) ◽  
pp. 1167-1168 ◽  
Author(s):  
David A. Pattison ◽  
Michael S. Hofman ◽  
Ali Bazargan ◽  
Peter Colman ◽  
Rodney J. Hicks

2010 ◽  
Vol 51 (9) ◽  
pp. e61-e64 ◽  
Author(s):  
N. E. Holmes ◽  
C. L. Gordon ◽  
N. Lightfoot ◽  
P. Crowley ◽  
R. R. Buchanan ◽  
...  

2019 ◽  
Vol 121 ◽  
pp. e364-e369 ◽  
Author(s):  
Erika Yamada ◽  
Eiichi Ishikawa ◽  
Rei Watanabe ◽  
Hideaki Matsumura ◽  
Noriaki Sakamoto ◽  
...  

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_1) ◽  
Author(s):  
Maria A Mirza

Abstract Background/Aims  Intravascular large b-cell lymphoma (IVLBCL) is a rare and aggressive form of extranodal diffuse lymphoma which due to its heterogeneous manifestations is often diagnosed at post mortem. The disease is typically contained within the small vessels thus sparing the surrounding tissue. Indeed, the presentation of the disease will depend on the organ involved with classical involvement of the central nervous system and skin. Methods  We herein report two compelling cases of patients presenting with features of myositis, only to find on muscle biopsy evidence of IVBCL. Biopsy of the affected area and indeed random skin biopsies (RSB) may be a fundamental tool in establishing this elusive diagnosis. Results  Features of the two cases are discussed, along with their various presentations, investigations, treatment and overall trajectory. Conclusion  IVBCL is a rare disease that can present in various ways and often a delay in reaching a diagnosis leads to patient deterioration and death. A multidisciplinary approach involving the microbiologists, rheumatologists and haematologists led to a timely identification of the disease and subsequent management in these two cases. As the disease is characteristically contained within the blood vessels, the diagnosis is normally not confirmed from peripheral blood tests or even bone marrow biopsy. Biopsy of the affected area is what revealed the diagnosis in our two cases. Random skin biopsies may be very useful in establishing the diagnosis when suspecting IVBCL. Treatment may be very effective in controlling the disease as demonstrated by these two cases. Disclosure  M.A. Mirza: None.


2013 ◽  
Vol 31 (17) ◽  
pp. e276-e279 ◽  
Author(s):  
Darko Antic ◽  
Nebojsa Petrovic ◽  
Mijomir Pelemis ◽  
Goran Stevanovic ◽  
Maja Perunicic ◽  
...  

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