Blenderized Enteral Nutrition Diet Study: Feasibility, Clinical, and Microbiome Outcomes of Providing Blenderized Feeds Through a Gastric Tube in a Medically Complex Pediatric Population

2018 ◽  
Vol 42 (6) ◽  
pp. 1046-1060 ◽  
Author(s):  
Kelsey Gallagher ◽  
Annika Flint ◽  
Marialena Mouzaki ◽  
Andrea Carpenter ◽  
Beth Haliburton ◽  
...  
Blood ◽  
1999 ◽  
Vol 94 (9) ◽  
pp. 3007-3014 ◽  
Author(s):  
W. Streif ◽  
M. Andrew ◽  
V. Marzinotto ◽  
P. Massicotte ◽  
A.K.C. Chan ◽  
...  

Abstract This study details warfarin use in a large pediatric population followed in a central anticoagulation clinic. A prospective, consecutive cohort of nonselected children were studied. Patients were divided into groups by age, target international normalized ratio (INR) range, disease, medications, and vitamin K supplemented enteral nutrition use. Groups were analyzed on multiple aspects of warfarin therapy using multivariate methods. A total of 319 patients received 352 warfarin courses representing 391 treatment years. Age independently influenced all aspects of therapy. When compared with all older children, the ≤1 year of age group required increased warfarin doses, longer overlap with heparin, longer time to achieve target INR ranges, more frequent INR testing and dose adjustments, and fewer INR values in the target range. Although significantly different than children ≤1 year, children 1 to 6 years of age showed the same findings when compared with 7- to 18-year-olds. Fontan patients required 25% decreased dosage as compared with other congenital heart disease patients. Children on corticosteroids had less INRs in the target range and children on phenobarbital/carbamazepine required increased maintenance dosages of warfarin. Also, patients receiving enteral nutrition required increased dosages of warfarin. Serious bleeding occurred in 2 children (0.5% per patient year). Recurrent thromboembolic events (TEs) occurred in 8 children. Two children had recurrences while receiving warfarin (1.3% per patient year). This study outlines the profound effect of age and relative complexity of clinical management of warfarin therapy in children.


2000 ◽  
Vol 118 (4) ◽  
pp. A1525
Author(s):  
William J. Owen ◽  
Peter C. Roberts ◽  
Richard J. Beale ◽  
Robert C. Mason

2019 ◽  
Vol 28 ◽  
Author(s):  
Juliana Nascimento ◽  
Inês Maria Meneses dos Santos ◽  
Laura Johanson da Silva

ABSTRACT Objective: to describe the conduct related to feeding care through gastric tube in neonates hospitalized in the Neonatal Intensive Care Unit, from scientific articles published in the last five years. Method: an integrative literature review was developed in the databases: MEDLINE, LILACS, SciELO, CINAHL and BDENF. The search for the studies was carried out in August 2016, in English, Spanish and Portuguese. Results: 33 articles were analyzed. The level of evidence was classified as level IV (30%), level VI (27%), level II (15%), level III (18%), level I, V and VII with 3% each. The analytical categories were: Gastric tubes, their materials and their use in the Neonatal Intensive Care Unit, Nursing care for enteral nutrition through gastric tube in the Neonatal Intensive Care Unit, From the tube the oral route. The time to reach total enteral nutrition is lower, as is the decrease in length of hospital stay. The largest losses of milk fat are during gastroclysis at the expense of gavage. The relationship of food tolerance to dietary dosage form and volumes is not yet conclusive. Nursing stands out: in favor of the bond with the family, in the physical examination and evaluation, in the positioning, in the non-nutritive suction during the diet, in the oral stimulus, in the observation and conduct regarding the gastric residue. Conclusion: due to the heterogeneity of the data, more randomized and qualitative clinical trials are required to better support the conduct and improvement of nursing care.


2021 ◽  
Vol 2 (2) ◽  
Author(s):  
Yangzhong Wang ◽  
Xiuqing Liao ◽  
Xiaoli Bao ◽  
Xianlin Peng ◽  
Nan Tang

We report a case of complete esophageal obstruction caused by continuous enteral nutrition infusion via nasogastric tube. A 77 year old man received mechanical ventilation due to severe pneumonia and severe respiratory distress. He began using enteral nutrition emulsion (TPF) through a nasogastric tube on admission. 15 days later, due to the difficulty of re-inserting the nasogastric tube, endoscopy found a large number of coagulations in the esophagus, resulting in complete esophageal obstruction. We remove a small part of the foreign body with a net basket under gastroscope. After the operation, the nasogastric tube was placed in the middle of the esophagus again, which was perfused with 5% sodium bicarbonate and vinegar through the gastric tube. One week later, the esophagus was completely unobstructed by gastroscopy. A conclusion can be drawn that the precipitation and coagulation of TPF can lead to the whole esophageal obstruction. Endoscopic removal of foreign bodies, sodium bicarbonate and vinegar retention in the esophagus can treat the food obstruction caused by TPF.


Blood ◽  
1999 ◽  
Vol 94 (9) ◽  
pp. 3007-3014 ◽  
Author(s):  
W. Streif ◽  
M. Andrew ◽  
V. Marzinotto ◽  
P. Massicotte ◽  
A.K.C. Chan ◽  
...  

This study details warfarin use in a large pediatric population followed in a central anticoagulation clinic. A prospective, consecutive cohort of nonselected children were studied. Patients were divided into groups by age, target international normalized ratio (INR) range, disease, medications, and vitamin K supplemented enteral nutrition use. Groups were analyzed on multiple aspects of warfarin therapy using multivariate methods. A total of 319 patients received 352 warfarin courses representing 391 treatment years. Age independently influenced all aspects of therapy. When compared with all older children, the ≤1 year of age group required increased warfarin doses, longer overlap with heparin, longer time to achieve target INR ranges, more frequent INR testing and dose adjustments, and fewer INR values in the target range. Although significantly different than children ≤1 year, children 1 to 6 years of age showed the same findings when compared with 7- to 18-year-olds. Fontan patients required 25% decreased dosage as compared with other congenital heart disease patients. Children on corticosteroids had less INRs in the target range and children on phenobarbital/carbamazepine required increased maintenance dosages of warfarin. Also, patients receiving enteral nutrition required increased dosages of warfarin. Serious bleeding occurred in 2 children (0.5% per patient year). Recurrent thromboembolic events (TEs) occurred in 8 children. Two children had recurrences while receiving warfarin (1.3% per patient year). This study outlines the profound effect of age and relative complexity of clinical management of warfarin therapy in children.


Critical Care ◽  
10.1186/cc543 ◽  
1999 ◽  
Vol 3 (Suppl 1) ◽  
pp. P170
Author(s):  
NH Boyle ◽  
PC Roberts ◽  
A McLuckie ◽  
WJ Owen ◽  
RJ Beale ◽  
...  

2021 ◽  
Author(s):  
Bojun Zheng ◽  
Jian Li ◽  
Yi Yu ◽  
Aijing Deng ◽  
Honglian Ouyang ◽  
...  

Abstract Background: Enteral nutrition is a major pathway of nutrition for patients requiring critical care. However, whether intermittent or continuous feeding is better is not yet known clearly, especially after nasogastric enteral nutrition via gastric tube. Therefore, this randomized controlled clinical study was designed to observe the effects of different methods on critically ill patients.Methods: The different feeding method on gastrointestinal function of critical patients (DFM-GFC) was a randomized, single-blind, clinical study assessing the effects of three feeding methods on critically ill patients. A total of 90 critical patients were equally randomized to three groups: continuous feeding, cycling feeding, and intermittent feeding. The patients were pumped with gastrointestinal nutrition preparation via gastric tube in 24 h or in 16 h via intermittent pump. The primary outcome is the mean duration that reached to the caloric goal in every group. The secondary outcome included the rate of onset of gastric residua, abdominal pressure, the rate of onset pneumonia, and the proportion of individuals achieving the caloric goal. Also, the length of intensive care unit (ICU) stay and mortality rate at 28 days post-enrollment was evaluated.Discussion: This study observes the effects of different feeding methods on parameters, such as energy target and gastrointestinal motility in critically ill patients, in order to improve the prognosis of, quality of life and reduce the case fatality rate.Trial registration: ClinicalTrials.gov ID: NCT04224883. Registered on January 9, 2020.


Sign in / Sign up

Export Citation Format

Share Document