Skin Abrasion

2013 ◽  
pp. 3114-3114
Keyword(s):  
2020 ◽  
Vol 137 (3) ◽  
pp. 167-173 ◽  
Author(s):  
YK Chin ◽  
MY Ina-Salwany ◽  
M Zamri-Saad ◽  
MNA Amal ◽  
A Mohamad ◽  
...  

2014 ◽  
Vol 25 (10) ◽  
pp. 969-974 ◽  
Author(s):  
Rachael L. Taylor ◽  
Mikael Schulin ◽  
Samanthi Goonetilleke ◽  
Miriam S. Welgampola

Background: In evoked potential testing, it is common practice to abrade the skin surface as a means of reducing and balancing electrode impedance. The effects of skin preparation and electrode impedance on ocular vestibular-evoked myogenic potential (oVEMP) prevalence and amplitudes are not known. Purpose: We sought to determine whether comparable oVEMP waveforms could be recorded without excessive skin preparation. Research Design: This was a prospective study with a repeated-measures (within-subjects) design. Study Sample: The study group comprised 20 healthy participants (12 females and 8 males) ages 21–57 yr. Data Collection and Analysis: oVEMP reflexes were recorded in response to air-conducted and bone-conducted (AC and BC) stimuli in three conditions. In the first condition (no skin preparation), electrodes were simply placed over the skin surface. For the second condition (moderate skin preparation), oVEMP testing was repeated after the skin had been prepared with 70% isopropyl alcohol swabs. oVEMPs recorded in these two conditions were then compared with those recorded using a third conventional protocol whereby the skin was abraded with skin preparation gel until electrode impedances were low and balanced. For BC stimuli, reflex amplitudes and latencies were compared using a repeated-measures general linear model. For AC stimuli, rates of reflex detection were analyzed using a generalized estimating equation. Nonparametric Friedman tests were used to compare AC oVEMP amplitudes across the three conditions. Results: There was no significant effect of electrode impedance on reflex amplitudes, latencies, or rates of detection (p > 0.05). The results indicated significant stimulus-related artifact (≥3 μV) in 25 of 40 recordings under the high-impedance condition in response to BC stimulation. The stimulus artifact was detectable in 12 of 40 recordings after moderate skin preparation and in 5 recordings after skin abrasion. Conclusions: Comparable rates of reflex detection and oVEMP amplitudes were recorded in the three conditions, implying that rigorous rubbing of the facial skin is largely unnecessary in clinical oVEMP testing. However, for oVEMPs recorded in response to a single-polarity stimulus, reducing and balancing electrode impedances with either isopropyl alcohol wipes or skin abrasion may help reduce unwanted stimulus artifact.


Blood ◽  
1977 ◽  
Vol 49 (3) ◽  
pp. 483-488 ◽  
Author(s):  
FR Appelbaum ◽  
L Norton ◽  
RG Jr Graw

Abstract Although granulocyte transfusion therapy has been shown to be effective in infected granulocytopenic animals and humans, the relative effectiveness of granulocytes (PMN) harvested by continuous flow centrifugation (CFC) or by continuous flow filtration leukapheresis (FL) remains uncertain. Studies in vitro of morphology and granulocyte functions have suggested cells collected by FL may be damaged. To compare the function in vivo of granulocytes collected by different methods, dogs were made granulocytopenic with cyclophosphamide (CYT) and then transfused with granulocytes collected by CFC or FL. The local neutrophil mobilization (LNM) through a standard skin abrasion into a chamber containing a strong chemoattractant, autologous serum, was measured. Greater LNM was found after transfusions of CFC PMN than after transfusions of the same number of FL PMN (p less than 0.0003). This difference persisted even when the dose of FL PMNs was four times greater than that of CFC mn and when the FL donor was pretreated with steroids (p less than 0.001). These results suggest that during filtration leukapheresis, granulocytes are functionally altered and that their function in vivo may be compromised.


2004 ◽  
Vol 12 (1) ◽  
pp. A14-A14
Author(s):  
Iijima Yuki ◽  
Tanaka Tatsunori ◽  
Yoneda Kei ◽  
Miyamoto Eiji

Blood ◽  
1977 ◽  
Vol 49 (3) ◽  
pp. 483-488
Author(s):  
FR Appelbaum ◽  
L Norton ◽  
RG Jr Graw

Although granulocyte transfusion therapy has been shown to be effective in infected granulocytopenic animals and humans, the relative effectiveness of granulocytes (PMN) harvested by continuous flow centrifugation (CFC) or by continuous flow filtration leukapheresis (FL) remains uncertain. Studies in vitro of morphology and granulocyte functions have suggested cells collected by FL may be damaged. To compare the function in vivo of granulocytes collected by different methods, dogs were made granulocytopenic with cyclophosphamide (CYT) and then transfused with granulocytes collected by CFC or FL. The local neutrophil mobilization (LNM) through a standard skin abrasion into a chamber containing a strong chemoattractant, autologous serum, was measured. Greater LNM was found after transfusions of CFC PMN than after transfusions of the same number of FL PMN (p less than 0.0003). This difference persisted even when the dose of FL PMNs was four times greater than that of CFC mn and when the FL donor was pretreated with steroids (p less than 0.001). These results suggest that during filtration leukapheresis, granulocytes are functionally altered and that their function in vivo may be compromised.


2020 ◽  
Vol 30 (6) ◽  
pp. 767-768
Author(s):  
Li-wen Zhang ◽  
Yan-jun Zhu ◽  
Tao Chen
Keyword(s):  

2010 ◽  
Vol 42 (1) ◽  
pp. 38-44 ◽  
Author(s):  
Tianhong Dai ◽  
George P. Tegos ◽  
Timur Zhiyentayev ◽  
Eleftherios Mylonakis ◽  
Michael R. Hamblin

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