Design and Development of Systemic Oral Mucosal Drug Delivery Systems

2015 ◽  
pp. 149-167 ◽  
Author(s):  
Michael John Rathbone ◽  
Sevda Şenel ◽  
Indiran Pather
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Design And Development ◽  
Mucosal Drug Delivery

Development of Innovative Orally Fast Disintegrating Film Dosage Forms: A Review

2012 ◽  
Vol 5 (2) ◽  
pp. 1666-1674 ◽  
Author(s):  
Bibhu Prasad Panda ◽  
N.S Dey ◽  
M.E.B. Rao
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Dosage Form ◽  
Geriatric Patients ◽  
Dosage Forms ◽  
Delivery Systems ◽  
Design And Development ◽  
Innovative Drug ◽  
Potential Benefits ◽  
Pharmaceutical Industries

Over the past few decades, there has been an increased interest for innovative drug delivery systems to improve safety, efficacy and patient compliance, thereby increasing the product patent life cycle. The discovery and development of new chemical entities is not only an expensive but also time consuming affair. Hence the pharmaceutical industries are focusing on the design and development of innovative drug delivery systems for existing drugs. One such delivery system is the fast disintegrating oral film, which has gained popularity among pediatric and geriatric patients. This fast disintegrating film with many potential benefits of a fast disintegrating tablet but devoid of friability and risk of choking is more acceptable to pediatric and geriatric patients. Formulation of fast disintegrating film can be achieved by various techniques, but common methods of preparation include spraying and casting. These film forming techniques use hydrophilic film former in combination with suitable excipients, which allow the film to disintegrate or dissolve quickly in the mouth within a few seconds without the administration of water. In view of the advantages of the fast disintegrating films over the fast disintegrating tablets and other dosage forms, it has the potential for commercial exploitation. The oral film dosage form not only has certain advantages of other fast disintegrating systems but also satisfies the unmet needs of the market. The present review emphasizes on the potential benefits, design and development of robust, stable, and innovative orally fast- disintegrating films and their future scenarios on a global market as a pharmaceutical dosage form.  

Design and development of lipid modified chitosan containing muco-adhesive self-emulsifying drug delivery systems for cefixime oral delivery

2021 ◽  
Vol 235 ◽  
pp. 105052
Author(s):  
Salim Saifullah ◽  
Tasmina Kanwal ◽  
Shafi Ullah ◽  
Muhammad Kawish ◽  
Shahida Muhammad Habib ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Oral Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Design And Development ◽  
Modified Chitosan

Design and development of controlled release intravaginal veterinary drug delivery systems

2000 ◽  
pp. 173-200 ◽  
Author(s):  
Michael J. Rathbone ◽  
Christopher R. Burke ◽  
Colin R. Ogle ◽  
Craig R. Bunt ◽  
Shane Burggraaf ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Veterinary Drug ◽  
Design And Development
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