The relationship between exposure duration, carboxyhemoglobin, blood glucose, pyruvate and lactate and the severity of intoxication in 39 cases of acute carbon monoxide poisoning in man

1985 ◽  
Vol 57 (3) ◽  
pp. 196-199 ◽  
Author(s):  
Jerzy A. Sokal ◽  
Ewa Kralkowska
Scientifica ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Makoto Onodera ◽  
Yasuhisa Fujino ◽  
Satoshi Kikuchi ◽  
Masayuki Sato ◽  
Kiyofumi Mori ◽  
...  

Objective. This study examined the hypothesis that correlations exist between the carbon monoxide exposure time and the carboxyhemoglobin concentration at the site of carbon monoxide poisoning, using a pulse carbon monoxide oximeter in rural areas or the carboxyhemoglobin concentration measured at a given medical institution.Background. In previous studies, no definitive relationships between the arterial blood carboxyhemoglobin level and the severity of carbon monoxide poisoning have been observed.Method. The subjects included patients treated for acute carbon monoxide poisoning in whom a medical emergency team was able to measure the carboxyhemoglobin level at the site of poisoning. We examined the relationship between the carboxyhemoglobin level at the site of poisoning and carbon monoxide exposure time and the relationships between the arterial blood carboxyhemoglobin level and carbon monoxide exposure time.Results. A total of 10 patients met the above criteria. The carboxyhemoglobin levels at the site of poisoning were significantly and positively correlated with the exposure time (rs = 0.710,p=0.021), but the arterial blood carboxyhemoglobin levels were not correlated with the exposure time.Conclusion. In rural areas, the carboxyhemoglobin level measured at the site of carbon monoxide poisoning correlated with the exposure time.


2022 ◽  
Author(s):  
Fan Zhang ◽  
Jiao Zeng ◽  
Xiaoli Zhang ◽  
Jiapeng Gu ◽  
Yongkai Han ◽  
...  

Abstract Background Increasing evidence reveals that delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) results from the combined effects of environmental and genetic factors. The main pathological feature of DEACMP was generalized demyelination of cerebral white matter. Myelin basic protein (MBP) levels in cerebrospinal fluid (CSF) and serum samples from DEACMP patients were elevated.Objectives This study investigated the association of MBP single nucleotide polymorphisms(SNPs) (rs470555, rs470724, rs4890785, rs595997, rs76452994, and rs921336) with DEACMP. Methods We genotyped 416 DEACMP patients and 785 age, educational level, and sex-matched ACMP patients for rs470555, rs470724, rs4890785, rs595997, rs76452994, and rs921336 SNPs using the Agena MassArray. Results There were no significant differences in the allele frequency distribution, four genetic models, and genotype distributions between the DEACMP and ACMP groups for rs470555, rs470724, rs4890785, and rs595997. However, significant differences were observed for rs76452994 and rs921336.Conclusions This study revealed that the MBP polymorphisms, rs470555, rs470724, rs4890785, and rs595997, were not associated with DEACMP. Based on the codominant, dominant, and overdominant genetic inheritability patterns, the MBP rs76452994 and rs921366 polymorphisms were associated with DEACMP. Furthermore, the G allele of rs76452994 and T allele of rs921336 could lead to higher DEACMP risk.


2013 ◽  
Vol 14 (1) ◽  
Author(s):  
Mounia Rahmani ◽  
Halima Belaidi ◽  
Maria Benabdeljlil ◽  
Wafa Bouchhab ◽  
Nadia El Jazouli ◽  
...  

1989 ◽  
Vol 45 (2-3) ◽  
pp. 207-213 ◽  
Author(s):  
David G. Penney ◽  
Kuldeep Verma ◽  
Julie A. Hull

The Lancet ◽  
1940 ◽  
Vol 236 (6118) ◽  
pp. 677-679
Author(s):  
J MCMICHAEL

2008 ◽  
Vol 15 (6) ◽  
pp. e49-e50 ◽  
Author(s):  
R. C. S. Seet ◽  
E. P. V. Wilder-Smith ◽  
E. C. H. Lim

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