Quantitative evaluation of hepatic fibrosis by fibro Scan and Gd-EOB-DTPA-enhanced T1 mapping magnetic resonance imaging in chronic hepatitis B

2021 ◽  
Author(s):  
Qingtao Li ◽  
Tianyou Chen ◽  
Nannan Shi ◽  
Wen Ye ◽  
Min Yuan ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Chronic Hepatitis ◽  
Magnetic Resonance ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Hepatic Fibrosis ◽  
Quantitative Evaluation ◽  
T1 Mapping ◽  
Resonance Imaging

scholarly journals Validity and Reliability of Magnetic Resonance Elastography for Staging Hepatic Fibrosis in Patients with Chronic Hepatitis B

2015 ◽  
Vol 14 (3) ◽  
pp. 211-221 ◽  
Author(s):  
Shintaro ICHIKAWA ◽  
Utaroh MOTOSUGI ◽  
Hiroyuki MORISAKA ◽  
Katsuhiro SANO ◽  
Tomoaki ICHIKAWA ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Magnetic Resonance ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Hepatic Fibrosis ◽  
Magnetic Resonance Elastography ◽  
Validity And Reliability

scholarly journals Magnetic Resonance Elastography and Diffusion Weighted Imaging in the Evaluation of Hepatic Fibrosis in Chronic Hepatitis B

Gut and Liver ◽  
2017 ◽  
Vol 11 (3) ◽  
pp. 401-408 ◽  
Author(s):  
Tiffany P. Hennedige ◽  
Gang Wang ◽  
Fiona P. Leung ◽  
Hind S. Alsaif ◽  
Lynette LS Teo ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Magnetic Resonance ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Hepatic Fibrosis ◽  
Diffusion Weighted Imaging ◽  
Magnetic Resonance Elastography ◽  
Diffusion Weighted ◽  
And Diffusion

scholarly journals Total Antioxidant Capacity in HBV Carriers, a Promising Biomarker for Evaluating Hepatic Fibrosis: A Pilot Study

Antioxidants ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 77
Author(s):  
Jing-Hua Wang ◽  
Sung-Bae Lee ◽  
Dong-Soo Lee ◽  
Chang-Gue Son
Keyword(s):  
Oxidative Stress ◽  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Antioxidant Capacity ◽  
Chronic Hepatitis B ◽  
Hepatic Fibrosis ◽  
Total Antioxidant Capacity ◽  
Hbv Dna ◽  
Total Antioxidant

Oxidative stress plays a pivotal role in the progression of chronic hepatitis B; however, it is unclear whether the status of blood oxidative stress and antioxidant components differs depending on the degree of hepatic fibrosis. To explore the relationship between oxidative stress/antioxidant capacity and the extent of hepatic fibrosis, fifty-four subjects with liver fibrosis (5.5 ≤ liver stiffness measurement (LSM) score ≤ 16.0 kPa) by chronic hepatitis B virus (HBV) were analyzed. From the analysis of eight kinds of serum oxidative stress/antioxidant profiles and liver fibrosis degrees, the level of total antioxidant capacity (TAC) reflected a negative correlation with the severity of hepatic fibrosis (Pearson correlation, r = −0.35, p = 0.01). Moreover, TAC showed higher sensitivity (73.91%) than the aspartate transaminase (AST) to platelet ratio index (APRI, 56.52%) in the receiver operating characteristic (ROC) curves. Interestingly, the TAC level finely reflected the fibrosis degree in inactive carriers (HBV DNA < 2000 IU/mL), while the APRI did in active carriers (HBV DNA > 2000 IU/mL). In conclusion, TAC is a promising biomarker for evaluating the progression of liver fibrosis in patients with HBV, and this finding may indicate the involvement of TAC-composing factors in the pathogenesis of hepatic fibrosis in chronic HBV carriers.

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