Functional MRI evidence for primary motor cortex plasticity contributes to the disease’s severity and prognosis of cervical spondylotic myelopathy patients

Author(s):  
Rui Zhao ◽  
Xing Guo ◽  
Yang Wang ◽  
YingChao Song ◽  
Qian Su ◽  
...  
Author(s):  
Noemi Piramide ◽  
Elisabetta Sarasso ◽  
Aleksandra Tomic ◽  
Elisa Canu ◽  
Igor N. Petrovic ◽  
...  

Radiology ◽  
2017 ◽  
Vol 282 (3) ◽  
pp. 817-825 ◽  
Author(s):  
Izabela Aleksanderek ◽  
Stuart M. K. McGregor ◽  
Todd K. Stevens ◽  
Sandy Goncalves ◽  
Robert Bartha ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Desmond Agboada ◽  
Mohsen Mosayebi Samani ◽  
Asif Jamil ◽  
Min-Fang Kuo ◽  
Michael A. Nitsche

AbstractSize and duration of the neuroplastic effects of tDCS depend on stimulation parameters, including stimulation duration and intensity of current. The impact of stimulation parameters on physiological effects is partially non-linear. To improve the utility of this intervention, it is critical to gather information about the impact of stimulation duration and intensity on neuroplasticity, while expanding the parameter space to improve efficacy. Anodal tDCS of 1–3 mA current intensity was applied for 15–30 minutes to study motor cortex plasticity. Sixteen healthy right-handed non-smoking volunteers participated in 10 sessions (intensity-duration pairs) of stimulation in a randomized cross-over design. Transcranial magnetic stimulation (TMS)-induced motor-evoked potentials (MEP) were recorded as outcome measures of tDCS effects until next evening after tDCS. All active stimulation conditions enhanced motor cortex excitability within the first 2 hours after stimulation. We observed no significant differences between the three stimulation intensities and durations on cortical excitability. A trend for larger cortical excitability enhancements was however observed for higher current intensities (1 vs 3 mA). These results add information about intensified tDCS protocols and suggest that the impact of anodal tDCS on neuroplasticity is relatively robust with respect to gradual alterations of stimulation intensity, and duration.


2020 ◽  
Vol 40 (24) ◽  
pp. 4788-4796 ◽  
Author(s):  
Andrea Guerra ◽  
Francesco Asci ◽  
Valentina D'Onofrio ◽  
Valerio Sveva ◽  
Matteo Bologna ◽  
...  

NeuroImage ◽  
1998 ◽  
Vol 7 (4) ◽  
pp. S616
Author(s):  
A. Schreiber ◽  
D. Jäger ◽  
C. Oesterle ◽  
M. Otte ◽  
J. Hennig

1996 ◽  
Vol 20 (5) ◽  
pp. 702-708 ◽  
Author(s):  
Andrea Righini ◽  
Oreste de Divitiis ◽  
Anna Prinster ◽  
Diego Spagnoli ◽  
Ildebrando Appollonio ◽  
...  

2018 ◽  
Vol 29 (7) ◽  
pp. 2924-2931 ◽  
Author(s):  
M Wischnewski ◽  
M Engelhardt ◽  
M A Salehinejad ◽  
D J L G Schutter ◽  
M -F Kuo ◽  
...  

Abstract Transcranial alternating current stimulation (tACS) has been shown to modulate neural oscillations and excitability levels in the primary motor cortex (M1). These effects can last for more than an hour and an involvement of N-methyl-d-aspartate receptor (NMDAR) mediated synaptic plasticity has been suggested. However, to date the cortical mechanisms underlying tACS after-effects have not been explored. Here, we applied 20 Hz beta tACS to M1 while participants received either the NMDAR antagonist dextromethorphan or a placebo and the effects on cortical beta oscillations and excitability were explored. When a placebo medication was administered, beta tACS was found to increase cortical excitability and beta oscillations for at least 60 min, whereas when dextromethorphan was administered, these effects were completely abolished. These results provide the first direct evidence that tACS can induce NMDAR-mediated plasticity in the motor cortex, which contributes to our understanding of tACS-induced influences on human motor cortex physiology.


NeuroImage ◽  
2003 ◽  
Vol 19 (4) ◽  
pp. 1349-1360 ◽  
Author(s):  
Maxime Guye ◽  
Geoffrey J.M Parker ◽  
Mark Symms ◽  
Philip Boulby ◽  
Claudia A.M Wheeler-Kingshott ◽  
...  

2002 ◽  
Vol 81 (11) ◽  
pp. 844-847 ◽  
Author(s):  
Sung Ho Jang ◽  
Bong Soo Han ◽  
Yongmin Chang ◽  
Woo Mok Byun ◽  
Jun Lee ◽  
...  

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