A case of solitary subependymal giant cell astrocytoma with histopathological anaplasia and TSC2 gene alteration

Author(s):  
Mario Suzuki ◽  
Akihide Kondo ◽  
Ikuko Ogino ◽  
Osamu Akiyama ◽  
Naohide Fujita ◽  
...  
Neurosurgery ◽  
1994 ◽  
Vol 35 (4) ◽  
pp. 748-750 ◽  
Author(s):  
Susumu Oikawa ◽  
Keizo Sakamoto ◽  
Norio Kobayashi

2005 ◽  
Vol 7 (4) ◽  
pp. 544-549 ◽  
Author(s):  
Tomotsugu Ichikawa ◽  
Akiko Wakisaka ◽  
Shigeru Daido ◽  
Soichiro Takao ◽  
Takashi Tamiya ◽  
...  

2016 ◽  
Vol 41 (4) ◽  
pp. E9 ◽  
Author(s):  
David Y. A. Dadey ◽  
Ashwin A. Kamath ◽  
Eric C. Leuthardt ◽  
Matthew D. Smyth

Subependymal giant cell astrocytoma (SEGA) is a rare tumor occurring almost exclusively in patients with tuberous sclerosis complex. Although open resection remains the standard therapy, complication rates remain high. To minimize morbidity, less invasive approaches, such as endoscope-assisted resection, radiosurgery, and chemotherapy with mTOR pathway inhibitors, are also used to treat these lesions. Laser interstitial thermal therapy (LITT) is a relatively new modality that is increasingly used to treat a variety of intracranial lesions. In this report, the authors describe two pediatric cases of SEGA that were treated with LITT. In both patients the lesion responded well to this treatment modality, with tumor shrinkage observed on follow-up MRI. These cases highlight the potential of LITT to serve as a viable minimally invasive therapeutic approach to the management of SEGAs in the pediatric population.


Neurosurgery ◽  
1991 ◽  
pp. 864 ◽  
Author(s):  
C W Shepherd ◽  
B W Scheithauer ◽  
M R Gomez ◽  
H J Altermatt ◽  
J A Katzmann

1979 ◽  
Vol 50 (1) ◽  
pp. 106-109 ◽  
Author(s):  
G. Michael Halmagyi ◽  
Leon P. Bignold ◽  
John L. Allsop

✓ A case is described of a subependymal giant-cell astrocytoma that occurred as a mural nodule within a cyst in the parietal lobe. The tumor recurred twice over a period of 47 years despite two extensive surgical resections. Neither the patient nor any of his children suffered tuberous sclerosis, a disease with which this type of astrocytoma is associated.


2018 ◽  
Vol 40 (5) ◽  
pp. 415-420 ◽  
Author(s):  
Ichiro Kuki ◽  
Hisashi Kawawaki ◽  
Shin Okazaki ◽  
Eiji Ehara ◽  
Yoko Yoshida ◽  
...  

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