scholarly journals Cross-Cultural Adaptation and Validation of the Italian Version of the Dysphagia Handicap Index (I-DHI)

Dysphagia ◽  
2021 ◽  
Author(s):  
Daniela Ginocchio ◽  
Aurora Ninfa ◽  
Nicole Pizzorni ◽  
Christian Lunetta ◽  
Valeria Ada Sansone ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Construct Validity ◽  
Intraclass Correlation ◽  
Oropharyngeal Dysphagia ◽  
Life Questionnaire ◽  
Retest Reliability ◽  
Dysphagia Handicap Index ◽  
Test Retest Reliability ◽  
Healthy Participants

AbstractThe Dysphagia Handicap Index (DHI) is a valid Health-related Quality of Life (HRQOL) questionnaire for patients with oropharyngeal dysphagia (OD) of heterogeneous etiologies. The study aimed at crossculturally translating and adapting the DHI into Italian (I-DHI) and analyzing I-DHI reliability, validity, and interpretability. The I-DHI was developed according to Beaton et al. 5-stage process and completed by 75 adult OD patients and 166 healthy adults. Twenty-six patients filled out the I-DHI twice, 2 weeks apart, for test–retest reliability purposes. Sixty-two patients completed the Italian-Swallowing Quality of Life Questionnaire (I-SWAL-QoL) for criterion validity analysis. Construct validity was tested comparing I-DHI scores among patients with different instrumentally assessed and self-rated OD severity, comparing patients and healthy participants and testing Spearman’s correlations among I-DHI subscales. I-DHI interpretability was assessed and normative data were generated. Participants autonomously completed the I-DHI in maximum 10 min. Reliability proved satisfactory for all I-DHI subscales (internal consistency: α > .76; test–retest reliability: intraclass correlation coefficient > .96, k = .81). Mild to moderate correlations (− .26 ≤ ρ ≤ − .72) were found between I-DHI and I-SWAL-QoL subscales. Construct validity proved satisfactory as (i) moderate to strong correlations (.51 ≤ ρ ≤ .90) were found among I-DHI subscales; (ii) patients with more severe instrumentally or self-assessed OD reported higher I-DHI scores (p < .05); and (iii) OD patients scored higher at I-DHI compared to healthy participants (p < .05). Interpretability analyses revealed a floor effect for the Emotional subscale only and higher I-DHI scores (p < .05) for healthy participants > 65 years. In conclusion, the I-DHI is a reliable and valid HRQOL tool for Italian adults with OD.

scholarly journals An Investigation of the Factor Structure of the Persian Version of the Dysphagia Handicap Index

2020 ◽  
Vol 7 (4) ◽  
Author(s):  
Ebrahim Barzegar Bafrooei ◽  
Seyyed Ahmadreza Khatoonabadi ◽  
Saman Maroufizadeh ◽  
Jalal Bakhtiyari ◽  
Ali rajaee
Keyword(s):  
Quality Of Life ◽  
Factor Analysis ◽  
Factor Structure ◽  
Oropharyngeal Dysphagia ◽  
Retest Reliability ◽  
Cronbach's Alpha ◽  
Persian Version ◽  
Dysphagia Handicap Index ◽  
Test Retest Reliability

Background: Oropharyngeal dysphagia harms all aspects of a person’s life, including behaviors, activities, and social situations. Quality of life is a multidimensional concept. The dysphagia handicap index (DHI) is a patient-reported outcomes tool that evaluates the different dimensions of quality of life in three physical, emotional, and functional factors in English-speaking countries. The validity of the Persian version of the dysphagia handicap index (DHI) has been evaluated in a study, but the reliability and factor analysis of the Persian version has not been investigated in any study. Objectives: This study aimed to investigate the factor structure analysis and reliability of the Persian version of the dysphagia handicap index (P-DHI). Methods: In this cross-sectional study, 100 patients with oropharyngeal dysphagia (mean age 55.69 ± 15.04, 53 women) completed the dysphagia handicap index (DHI). The severity of dysphagia was defined as follows: 1 for no dysphagia (normal), 2 and 3 for mild, 4, and 5 for moderate and 6 and 7for severe. Construct validity was examined by confirmatory factor analysis (CFA). Cronbach’s alpha and intraclass correlation coefficient (ICC) were performed to evaluate the internal consistency and test-retest reliability of the P-DHI, respectively. Results: The results of CFA provided support for a second-order three-factor model of P-DHI (χ2 = 484.61, df = 273, (P = 0.0001), χ2/df = 1.77; CFI = 0.901; RMSEA = 0.088 and SRMR = 0.010). The Cronbach’s alpha for physical, functional, and emotional subscales and total score were 0.751, 0.836, 0.773, and 0.900, respectively. The test-retest reliability of the P-DHI for the total score and subscales was high (ICC: 0.952 - 0.988). Furthermore, a significant relationship was found between the P-DHI total score and self-reported severity of dysphagia (P = 0.0001), while there were no relationships between P-DHI total score and age (P = 0.223), sex (P = 0.936), level of education (P = 0.113), disease duration (P = 0.126). Conclusions: The P-DHI is a reliable and valid instrument for assessing the disabling effects of swallowing disorders on the one’s Quality of Life in Iranian patients with oropharyngeal dysphagia due to a variety of diseases. Also, the CFA findings provide support for the tree-factor structure of the P-DHI and the use of the subscales as distinct variables.

scholarly journals Psychometric Validation of the German Translation of the Quality of Life Questionnaire-Bronchiectasis (QOL-B)—Data from the German Bronchiectasis Registry PROGNOSIS

2022 ◽  
Vol 11 (2) ◽  
pp. 441
Author(s):  
Laura Quellhorst ◽  
Grit Barten-Neiner ◽  
Andrés de Roux ◽  
Roland Diel ◽  
Pontus Mertsch ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Social Functioning ◽  
Emotional Functioning ◽  
Psychometric Validation ◽  
Life Questionnaire ◽  
Retest Reliability ◽  
German Translation ◽  
Quality Of Life Questionnaire ◽  
Test Retest Reliability

Patients with bronchiectasis feature considerable symptom burden and reduced health-related quality of life (QOL). We provide the psychometric validation of the German translation of the disease-specific Quality of Life Questionnaire-Bronchiectasis (QOL-B), version 3.1, using baseline data of adults consecutively enrolled into the prospective German bronchiectasis registry PROGNOSIS. Overall, 904 patients with evaluable QOL-B scores were included. We observed no relevant floor or ceiling effects. Internal consistency was good to excellent (Cronbach’s α ≥0.73 for each scale). QOL-B scales discriminated between patients based on prior pulmonary exacerbations and hospitalizations, breathlessness, bronchiectasis severity index, lung function, sputum volume, Pseudomonas aeruginosa status and the need for regular pharmacotherapy, except for Social Functioning, Vitality and Emotional Functioning scales. We observed moderate to strong convergence between several measures of disease severity and QOL-B scales, except for Social and Emotional Functioning. Two-week test-retest reliability was good, with intraclass correlation coefficients ≥0.84 for each scale. Minimal clinical important difference ranged between 8.5 for the Respiratory Symptoms and 14.1 points for the Social Functioning scale. Overall, the German translation of the QOL-B, version 3.1, has good validity and test-retest reliability among a nationally representative adult bronchiectasis cohort. However, responsiveness of QOL-B scales require further investigation during registry follow-up.

Test/retest study of the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire.

1995 ◽  
Vol 13 (5) ◽  
pp. 1249-1254 ◽  
Author(s):  
M J Hjermstad ◽  
S D Fossa ◽  
K Bjordal ◽  
S Kaasa
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Reliability And Validity ◽  
Life Questionnaire ◽  
European Organization ◽  
Retest Reliability ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Test Retest Reliability

PURPOSE The European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) is a well-validated instrument that assesses health-related quality of life (HRQOL) in cancer patients. It is used in cancer clinical trials in Europe, Canada, and the United States, and has demonstrated high reliability and validity in different groups of cancer patients. Despite thorough testing of reliability and validity, we have not identified any reports on its test/retest reliability; thus, a test/retest study was performed at the Norwegian Radium Hospital (NRH). MATERIALS AND METHODS Cancer patients from the outpatient clinic who were off treatment for > or = 3 months were eligible for the study. The EORTC QLQ-C30 was given to the patients when they presented for their visit. The second questionnaire was received by the patients 4 days later. Of 291 eligible patients, 270 (93%) agreed to participate and 190 (73%) completed both questionnaires. RESULTS The test/retest reliability measured by Pearson's correlation coefficient was high for all functional scales, with a range from .82 for cognitive and role function to .91 for physical function. The r value for global HRQOL was .85. For the symptom scales--nausea/vomiting, fatigue, and pain--the coefficients were .63, .83, and .86, respectively. The single-item coefficients ranged from .72 for diarrhea to .84 for financial impact. The Spearman rank correlation was in the same range for all dimensions. CONCLUSION The EORTC QLQ-C30 seems to yield high test/retest reliability in patients with various cancer diagnoses whose condition is not expected to change during the time of measurement.

Reliability and Validity of Turkish Myasthenia Gravis-Activities of Daily Living Scale

2020 ◽  
pp. 153944922096107
Author(s):  
Ecem Karanfil ◽  
Yeliz Salcı ◽  
Ayla Fil-Balkan ◽  
Can Ebru Bekircan-Kurt ◽  
Sevim Erdem Özdamar ◽  
...  
Keyword(s):  
Construct Validity ◽  
Myasthenia Gravis ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Intraclass Correlation ◽  
Reliability And Validity ◽  
Life Questionnaire ◽  
Good Test ◽  
Retest Reliability ◽  
Test Retest Reliability

Linguistic, reliable, and valid secondary efficacy measures are important in clinical settings and studies. The aim of the study is to report test–retest reliability and construct validity of Turkish version of Myasthenia Gravis-Activities of Daily Living Scale (MG-ADL-T) in Myasthenia Gravis (MG) patients. Fifty-two ocular and generalized individuals with MG, applying to rehabilitation center, were included in the study. MG-ADL-T, MG quality-of-life questionnaire (MG-QoL), MG composite (MGC), quantitative MG score (QMGS), and pulmonary function test were administered. Reliability was assessed with intraclass correlation coefficient (ICC) and Cronbach’s alpha. Spearman correlation test and receiver operating characteristic (ROC) analysis were performed for construct validity. MG-ADL-T had fair internal consistency (Cronbach’s α = .67), excellent test–retest reliability (ICC = 0.96) and moderate construct validity (MG-QoL, r = 0.59; QMGS, r = .58; MGC, r = .68). MG-ADL, a unique scale that evaluates activities of daily living (ADL), has good test–retest reliability and construct validity in Turkish MG patients.

Measuring Patient-Reported Health-Related Quality of Life in Velopharyngeal Insufficiency: Reliability and Validity of the Brazilian Portuguese Version of the VELO Instrument

2019 ◽  
Vol 56 (9) ◽  
pp. 1195-1205 ◽  
Author(s):  
Rafael Denadai ◽  
Cassio Eduardo Raposo-Amaral ◽  
Anelise Sabbag ◽  
Rafael Andrade Ribeiro ◽  
Celso Luiz Buzzo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Construct Validity ◽  
Internal Consistency ◽  
Reliability And Validity ◽  
Brazilian Portuguese ◽  
Velopharyngeal Insufficiency ◽  
Retest Reliability ◽  
Related Quality ◽  
Test Retest Reliability

Objective: To test the Brazilian Portuguese velopharyngeal insufficiency (VPI) Effects on Life Outcome (VELO) instrument for reliability and validity. Design: Cross-sectional methodological study. Setting: Tertiary craniofacial medical center. Participants: Participants with VPI (VPI group, n = 60), with cleft and without VPI (no VPI/cleft group, n = 60), and with no cleft nor VPI (no VPI/no cleft group, n = 60) and their parents (n = 180). Interventions: All patients with VPI 8+ years old and their parents completed the Brazilian–Portuguese VELO instrument and other questionnaires (Pediatric Quality of Life Inventory4.0, PedsQL4.0; Pediatric Voice-Related Quality of Life, PVRQOL; and Intelligibility in Context Scale, ICS) at baseline; patients with VPI and their parents completed the VELO instrument again 2 weeks later. Main Outcome Measures: The VELO instrument was tested for internal consistency, test–retest reliability, discriminant validity (participants with VPI against participants with no VPI), concurrent validity against other questionnaires, criterion validity against hypernasality severity, and construct validity against nasal air emission and overall velopharyngeal competence (speech construct) and velopharyngeal gap (anatomic construct). Results: The VELO had excellent internal consistency (Cronbach α 0.99 for parents and 0.98 for participants with VPI) and test–retest reliability (all intraclass correlation coefficient > 0.87). The VELO discriminated well between VPI group and unaffected groups (all P < .05). The VELO was significantly correlated with the PedsQL4.0, PVRQOL, and ICS (– r > 0.75; P < .001). The VELO met criterion validity, speech construct validity, and anatomic construct validity ( r > 0.7; P < .001). Conclusions: The Brazilian-Portuguese VELO instrument demonstrated reliability (internal consistency and test–retest) and validity (discriminant, concurrent, criterion, and construct).

The most troublesome aspects of quality of life for people with advanced cancer in a supportive care trial

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 18527-18527
Author(s):  
A. K. Nowak
Keyword(s):  
Quality Of Life ◽  
Advanced Cancer ◽  
Intraclass Correlation ◽  
Well Being ◽  
Dry Mouth ◽  
Single Item ◽  
Retest Reliability ◽  
Data Form ◽  
Test Retest Reliability

18527 Background: ZEST is a placebo-controlled trial of sertraline for people with advanced cancer who feel depressed, anxious or tired but do not have a clear indication for antidepressants. We describe here the aspects of quality of life (QL) rated most troublesome at baseline by the first 150 subjects. Methods: Subjects completed a battery of QL questionnaires including the CES-D, HADS, FACT-G, FACT-Fatigue, and the Patient Disease and Treatment Assessment Form (Pt DATA Form). The Pt DATA Form assesses pertinent symptoms and concerns using 40 single items with a uniform response scale from 0 (no trouble at all) to 10 (worst I can imagine). Test-retest reliability was assessed with the intraclass correlation coefficient (ICC). Convergent validity was assessed by testing correlations between single items from the PT DATA Form and the corresponding, validated, multi-item scales. Results: The median age was 66 (IQR 59 to 73); median Karnofsky Perfomance Status was 80 (IQR 70 to 90); 63% were male; commonest primaries were colorectal (17%), lung (16%), prostate, (14%), breast (13%), and gynaecologic (10%). The aspects rated worst (mean score, proportion scoring >3) were: Fatigue (5.5, 90%), Problems with sex (4.1, 51%), Trouble sleeping (3.6, 49%), Drowsiness (3.5, 54%), Not feeling myself (3.5, 51%), Pain (3.4, 45%), Shortness of breath (3.4, 47%), Problems doing what I wanted (3.1, 45%), Anxiety (3.0, 40%), Depression (2.7, 36%), Dry mouth (2.7, 38%), Trouble concentrating (2.7, 30%), Irritability (2.6, 32%), Altered sense of taste (2.5, 34%), Difficulty walking (2.4, 32%), and Constipation (2.1, 24%). Mean scores were higher in men than women for Problems with sex (5.0 v 2.4, p < 0.001); and, in subjects aged 65 or younger for Hair loss (2.4 v 1.1, p = .01). There were no other significant differences by gender or age. Correlations supported the validity of the single item scales for depression, anxiety, fatigue; and for physical, emotional and overall well-being. The test-retest reliability of the Pt DATA Form was good (ICC >0.5 for 34 of 40 items). Conclusions: Pertinent aspects of QL were validly measured with single item scales. Insomnia, dry mouth, altered sense of taste and irritability were more troublesome than many other, better studied symptoms. No significant financial relationships to disclose.

scholarly journals Hitting The Bullseye: The Psychometric Properties of the Assessment of Burden of Chronic Conditions (ABCC)-Scale in The Netherlands

2021 ◽  
Author(s):  
Danny Claessens ◽  
Esther A. Boudewijns ◽  
Lotte C.E.M. Keijsers ◽  
Annerika H.M. Gidding-Slok ◽  
Bjorn Winkens ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Conditions ◽  
Convergent Validity ◽  
Life Questionnaire ◽  
Cronbach’S Alpha ◽  
Retest Reliability ◽  
Quality Of Life Questionnaire ◽  
Cronbach's Alpha ◽  
Test Retest Reliability

Abstract Background Chronic conditions impose a major impact on quality of life and on healthcare. The Assessment of Burden of Chronic Conditions (ABCC-)tool was developed to improve experienced quality of care and quality of life by facilitating shared decision-making and self-management. It assesses the experienced burden of one or multiple conditions, and visualises and integrates the burden in daily care. However, its scale’s validity and reliability are yet unknown. The aim of this study is to evaluate whether the ABCC-scale is valid and reliable in people with Chronic Obstructive Pulmonary Disease (COPD), asthma, or Type 2 Diabetes Mellitus (T2DM). Methods The Saint George Respiratory Questionnaire (SGRQ), the Standardized Asthma Quality of Life Questionnaire (AQLQ-S), and the Audit of Diabetes Dependent Quality of Life Questionnaire (ADDQoL19) were compared to the ABCC-scale to assess convergent validity. Convergent validity was assumed when at least 75% of the postulated correlations were higher than 0.7, or between 0.3 and 0.7 for single-item subscales. To measure known-group validity, participants were categorized according to exacerbation status, depression, asthma control, insulin dependence, complications and obesity. The ABCC-scale was deemed internally consistency upon a Cronbach’s alpha ≥ 0.90 for the total scale, and ≥ 0.70 for subscales. Test-retest reliability was evaluated at a two-week interval. Results A total of 65, 62, and 60 people with COPD, asthma, T2DM respectively were included. The ABCC-scale correlated, in accordance with hypotheses, with the SGRQ (75%), AQLQ-S (100%), and ADDQoL19 (75%). Differentiation of known-groups based on the ABCC-scale was possible for all specified groups. The total score and subscores of the ABCC-scale were internally consistent with a Cronbach’s alpha of 0.90, 0.92, and 0.91 for the total score for people with COPD, asthma, and T2DM respectively. The ABCC-scale had a good test-retest reliability with an Intraclass Correlation Coefficient of 0.95, 0.93, and 0.95 for people with COPD, asthma and T2DM respectively. Conclusions The ABCC-scale is a valid and reliable questionnaire that can be used within the ABCC-tool for people with COPD, asthma or T2DM. Future research should indicate whether this also applies to people with multimorbidity, and what the effects and experiences are upon clinical use.

scholarly journals Validation of the Iranian Version of the ECOS-16 Questionnaire in Patients with Osteoporotic Vertebral Fractures

2017 ◽  
Vol 11 (4) ◽  
pp. 586-593
Author(s):  
Parisa Azimi ◽  
Taravat Yazdanian ◽  
Ali Montazeri
Keyword(s):  
Quality Of Life ◽  
Psychometric Properties ◽  
Vertebral Fractures ◽  
World Health ◽  
Life Questionnaire ◽  
Retest Reliability ◽  
Osteoporotic Vertebral Fractures ◽  
Sf 36 ◽  
Test Retest Reliability

<sec><title>Study Design</title><p>Prospective clinical study.</p></sec><sec><title>Purpose</title><p>To translate and validate the Quality of Life Questionnaire of the European Foundation for Osteoporosis (ECOS-16) in patients with osteoporotic vertebral fractures in Iran.</p></sec><sec><title>Overview of Literature</title><p>It is important to assess the psychometric properties of instruments measuring patient-reported outcomes.</p></sec><sec><title>Methods</title><p>The translation was performed using the backward-forward translation method. The final version was generated by consensus among the translators. Every woman who had a T-score of &lt;−2.5 completed ECOS-16. Patients were divided into two study groups according to the World Health Organization's criteria: those with at least one vertebral fracture (surgery group) and those with no fractures (control group). They were asked to respond to the questionnaire at three points in time: preoperative and twice within 1-week interval after surgery assessments (6-month follow-up). The 36-item short-form health survey (SF-36) also was completed. The psychometric properties of the questionnaire were assessed using internal consistency, test-retest reliability, convergent validity, discriminant validity, and responsiveness.</p></sec><sec><title>Results</title><p>Of 137 recruited women, 39 underwent surgery and 98 did not. Analysis of the ECOS-16 scales showed an appropriate reliability with Cronbach's alpha of &gt;0.70 for all scales. Test-retest reliability as indicated by intraclass correlation coefficient was found to be 0.85 (0.68–0.91). Additionally, the correlation of each item with its hypothesized domain of the ECOS-16 showed acceptable results, suggesting that the items had a substantial relationship with their own domains. Further analysis also indicated that the questionnaire was responsive to change (effect size, 0.85; standardized response mean, 0.93) (<italic>p</italic>&lt;0.001). Significant correlations existed between scores of similar subscales of ECOS-16 and SF-36 (<italic>p</italic>&lt;0.001).</p></sec><sec><title>Conclusions</title><p>ECOS-16 is an acceptable, reliable, valid, and responsive measure to assess the quality of life in patients with osteoporotic vertebral fractures.</p></sec>

scholarly journals The construction and validation of the Severe Asthma Questionnaire

2018 ◽  
Vol 52 (1) ◽  
pp. 1800618 ◽  
Author(s):  
Michael E. Hyland ◽  
Rupert C. Jones ◽  
Joseph W. Lanario ◽  
Matthew Masoli
Keyword(s):  
Quality Of Life ◽  
Severe Asthma ◽  
Convergent Validity ◽  
Life Questionnaire ◽  
Retest Reliability ◽  
Qualitative And Quantitative ◽  
Quality Of Life Scale ◽  
Global Quality Of Life ◽  
Test Retest Reliability

The US Food and Drug Administration's procedure for scale validation requires a documented stepwise process of qualitative and quantitative data. The aim of this paper is to provide final quantitative validating data for the Severe Asthma Questionnaire (SAQ).The SAQ, Asthma Control Test, Mini Asthma Quality of Life Questionnaire and EQ-5D-5L were completed by 160 patients attending a severe asthma clinic; 51 patients completed the SAQ on two occasions for test–retest reliability analysis. The SAQ produces two scores, a SAQ score based on the average of 16 items and a SAQ-global score from a single 100-point global quality of life scale.Construct validity was demonstrated by factor analysis of the 16 items, convergent validity by correlations of >0.6 between the SAQ, SAQ-global and other questionnaires, and discriminant validity by the ability of the SAQ and SAQ-global to distinguish between different treatment levels. Test–retest reliability (intra-class correlation) was 0.93 for the SAQ and 0.93 for the SAQ-global, and the alpha coefficient for the SAQ was 0.93.The SAQ was developed using recommended qualitative and quantitative procedures for scale development, and can be used to gain insight into patients’ perceptions of how severe asthma and its treatment affects their lives.

scholarly journals Validity, reliability, and sensitivity to change of the Thai version of the Migraine-Specific Quality of Life Questionnaire version 2.1

2018 ◽  
Vol 11 (4) ◽  
pp. 331-342
Author(s):  
Thanin Asawavichienjinda ◽  
Pongpat Vorasayan ◽  
Jirawadee Noiwattanakul ◽  
Kammant Phanthumchinda
Keyword(s):  
Quality Of Life ◽  
Internal Consistency ◽  
Life Questionnaire ◽  
Sensitivity To Change ◽  
Retest Reliability ◽  
Associated Symptoms ◽  
Questionnaire Version ◽  
Test Retest Reliability

AbstractBackgroundThe Migraine-Specific Quality of Life Questionnaire version 2.1 (MSQv2.1) is used to evaluate the impact of symptoms on the quality of life (QoL) of migraineurs.ObjectiveTo evaluate primarily the concurrent validity, test–retest reliability, and internal consistency, and secondarily the sensitivity to change of a Thai version of the MSQv2.1.MethodsThe original English version of the MSQv2.1 was translated into a Thai version. The Thai version of the MSQv2.1 was assessed for content and language equivalence. Validity of the Thai version of the MSQv2.1 was assessed using migraine characteristics in a prospective study conducted at the Chulalongkorn Comprehensive Headache Centre of King Chulalongkorn Memorial Hospital. Test–retest reliability and internal consistency were tested in migraineurs. Sensitivity to change was evaluated in another group of migraineurs using an 8-week follow-up.ResultsWe recruited 30 migraineurs to test the validity, test–retest reliability, and internal consistency of the Thai version of the MSQv2.1 and 11 migraineurs to test its sensitivity to change. The Thai version of the MSQv2.1 scores were significantly correlated with migraine symptoms (inverse coefficient range from –0.62 to –0.39) except for associated symptoms, which had no correlation with any of the dimensions or overall QoL score. Spearman’s correlation coefficient for test–retest reliability was 0.56–0.83, and Cronbach’s α for internal consistency was 0.91–0.96. Headache, including average pain duration per attack, pain severity score (numeric rating scale), associated symptoms and dimensions, and overall QoL score of the Thai version of MSQv2.1 improved over time (P < 0.05). Moreover, improvement in headache correlated (coefficient range 0.67–0.77) with improvement in overall QoL score and some dimensions of the Thai version of the MSQv2.1 (coefficient range 0.66–0.77).ConclusionThe Thai version of the MSQv2.1 had validity, acceptable internal consistency, moderate-to-strong test–retest reliability, and strong correlation between improvement in headache severity and overall QoL score. A future study with a larger sample size and longer follow-up is required for better estimates of internal consistency and sensitivity to change.

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