scholarly journals Is fresh, leucodepleted, whole blood transfusion superior to blood component transfusion in pediatric patients undergoing spinal deformity surgeries? A prospective, randomized study analyzing postoperative serological parameters and clinical recovery

Author(s):  
P. Keerthi Vasan ◽  
S. Rajasekaran ◽  
Vibhu Krishnan Viswanathan ◽  
Ajoy Prasad Shetty ◽  
Rishi Mugesh Kanna
2021 ◽  
Author(s):  
Harriet Tucker ◽  
Laura Green ◽  
Karim Brohi ◽  
Rebecca Cardigan ◽  
Ross Davenport ◽  
...  

Abstract BackgroundPre-hospital blood component transfusion poses logistical challenges. Current patterns of pre-hospital blood use across the UK are not known. A potential benefit of providing a single combined component of whole blood is reduced need for multiple steps of administering separate components and more efficient use of time and resources by medical staff. .Objectivesto undertake a detailed time-analysis of the steps of pre-hospital combined component transfusion against separate blood component transfusion, and to determine current UK pre-hospital transfusion practice and users’ optimal pre-hospital transfusion strategyMethodsA three-arm cross-over major haemorrhage simulation study compared: flow-time (time from decision-to-transfuse [DTT] to complete transfusion); touch-time (direct team ’hands on’ contact time with transfusion process); and number of steps, people and equipment required for transfusion of 2 units of RCP [arm-A], 2 RBC + 2 TP [arm-B] or RBC + 2 Lyoplas [arm-C]). A national survey of current and optimal pre-hospital transfusion strategies was sent to 22 UK Air Ambulance Services (AAS) and 27 Major Trauma Centres (MTC) in December 2019. ResultsThe simulation demonstrated that arm-A had a shorter flow-time (median 6min 31sec vs. 12min 20 sec, vs 16min 29 sec) and touch-time (median 2min 31 seconds vs. 5min 21sec vs. 15min 3sec) than arm-B and arm-C respectively, and required fewer steps, equipment and checks. 18 MTCs and 18 AAS responded to the national survey (response rates of 67 and 82%). 10 transfused RBC/plasma (5 TP/5 Lyoplas), 4 RBC only, 2 Lyoplas only, 1 RBC/Lyoplas/Fibrinogen, and 1 ’red cell and plasma’ (only available at one hospital site). 89% replied that a combined component transfusion would be desirable, as it would reduce patient mortality (83%) and tasks on scene (75%). ConclusionThe time-analysis established the benefits for combined pre-hospital component transfusion in trauma patients. The national survey demonstrates the variation in current pre-hospital transfusion practice and reiterates that combined component transfusion pre-hospital may have logistical advantages over separate components.


1970 ◽  
Vol 19 (2) ◽  
pp. 50-56
Author(s):  
ABM Golam Robbani ◽  
MA Salam ◽  
AKM Anowarul Islam

 In a prospective, randomized study, 80 patients with lower urinary tract symptoms (LUTS) caused by small prostate gland (estimated weight <30gm) had either transurethral resection (TURP, n=40) or transurethral incision (TUIP, n=40) of prostate. The study was conducted in the Department of Urology, BSMMU, Dhaka and Rajshahi Medical College Hospital, Rajshahi. Aims of the study were to evaluate the efficacy of TUIP as a treatment modality for small size obstructive BPH and to compare its outcome with that of TURP. A relative advantage of TUIP over conventional TURP was also observed in this study. Preoperative variables (symptom scores, PVR, uroflowmetry parameters) were well matched in between TURP and TUIP group.TURPs were done in conventional technique. For TUIP, two deep incisions were made at 5- and 7-0'clock positions of the bladder neck using Colling's knife. Operative variables (operating time, amount of irrigation fluid and blood transfusion required) were observed and recorded. Postoperative catheterization period and hospital stay (in days) were noted.All patients were followed up at 3 to 4 months postoperatively. Changes of preoperative variables following surgery were assessed. Sexual functions were also questioned and noted pre- and postoperatively.The study clearly indicated that TUIP is as effective as TURP for the treatment of small sized obstructive BPH. Alterations of sexual functions are similar in both the procedures. On the other hand, operating time, requirement of irrigation fluid and blood transfusion, postoperative catheterization period and hospital stay are significantly (P>0.001) less in TUIP group than that of TURP.In conclusion, we recommend TUIP for the treatment of LUTS caused by small size obstructing benign prostatic hyperplasia.   doi: 10.3329/taj.v19i2.3149 TAJ 2006; 19(2): 50-56


Author(s):  
Anjali Handa ◽  
Sunita Bundas ◽  
Ashok Pal

Background: Blood is the most precious gift for human life. Blood transfusion services play a vital role in managing health care services. There is no substitute for blood and its components till date, therefore blood donation drive is very crucial. The primary responsibility of blood transfusion services is to provide safe, sufficient and timely supply of blood and blood products. There has been shift for usage of blood and blood components from the use of whole blood so that maximum utilization of this precious resource could be done. Aim and objectives was to study pattern of utilization of blood and blood components in a super speciality hospital with the indications for transfusions for different components during the study period.Methods: This retrospective study for 12 months (January 2019- December 2 019) on pattern of utilization of blood components was carried out in the department of immunohaematology and transfusion medicine in a super speciality hospital.Results: There were total of 90237 transfusions which were carried out during the study period of 12 months. During the study period, 366 stored whole blood units, 55300 Packed RBC units, 19111 FFP units, 14298 Random Donor Platelet units, 1119 single donor platelets and 43 cryoprecipitate units were issued for use in patients admitted to our hospital.Conclusions: Periodic review and audit of blood component usage becomes essential to assess the blood utilization pattern in any hospital.  


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