scholarly journals The influence of spinal position on imaging findings: an observational study of thoracolumbar spine upright MRI in elite gymnasts

Author(s):  
Louise Fawcett ◽  
Steven James ◽  
Rajesh Botchu ◽  
James Martin ◽  
Nicola R. Heneghan ◽  
...  

Abstract Purpose To investigate whether upright magnetic resonance imaging (MRI) has a role in defining thoracolumbar spine pathology in elite gymnastics. Methods A prospective cross-sectional observational study of National Senior and Junior Artistic gymnasts in three MRI positions (standard supine, upright flexed and extended positions). Two specialist musculoskeletal radiologists independently analysed images with neutral as a baseline with the effects of flexion and extension reported in line with Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement. Results Forty (18 males) gymnasts aged 13–24 years with a mean (SD) of 32 (5.3) training hours per week consented with 75% showing MRI abnormalities. Degenerative disc disease (DDD) was evident in 55% participants with vertebral end plate (VEP) changes in 42.5%. Spondylolysis was present in 40% with an additional 17% showing chronic bilateral complete L5 pars defects. 23% participants demonstrated different MRI findings in upright flexion compared to neutral. Conclusion Findings suggest a high levels of MRI abnormalities in elite gymnastics including altered disc morphology and posterior element abnormalities. High prevalence of T11/12 DDD and VEP changes reflects the thoracolumbar junction being a transition zone. Upright MRI and varying spine position offer promise for enhanced visualisation of posterior element abnormalities.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Seiya Ota ◽  
Eiji Sasaki ◽  
Shizuka Sasaki ◽  
Daisuke Chiba ◽  
Yuka Kimura ◽  
...  

AbstractWe investigated the prevalence of magnetic resonance imaging (MRI) findings and their relationship with knee symptoms in women without radiographic evidence of knee osteoarthritis (KOA). This cross-sectional cohort study included 359 Japanese women without radiographic evidence of KOA (Kellgren‒Lawrence grade < 2). All participants underwent T2-weighted fat-suppressed MRI of their knees. Structural abnormalities (cartilage damage, bone marrow lesions [BMLs], subchondral cysts, bone attrition, osteophytes, meniscal lesions, and synovitis) were scored according to the whole-organ MRI score method. Knee symptoms were evaluated using the Knee Injury and Osteoarthritis Outcome Score. Participants were divided into early and non-KOA groups based on early KOA classification criteria. Logistic regression analysis was performed to evaluate the relationship between MRI abnormalities and knee symptoms. Cartilage damage was the most common abnormality (43.5%). The prevalences of cartilage damage, BMLs, subchondral cysts, bone attrition, meniscal lesions, and synovitis were higher in patients with early KOA than in those without. Synovitis (odds ratio [OR] 2.254, P = 0.002) and meniscal lesions (OR 1.479, P = 0.031) were positively associated with the presence of early KOA. Synovitis was most strongly associated with knee pain and might be a therapeutic target in patients with early KOA.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Lynnea Myers ◽  
Mai-Lan Ho ◽  
Elodie Cauvet ◽  
Karl Lundin ◽  
Torkel Carlsson ◽  
...  

AbstractWhile previous research has investigated neuroradiological findings in autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD), the entire range of neurodevelopmental disorders (NDDs) has not yet been well-studied using magnetic resonance imaging (MRI). Considering the overlap among NDDs and simultaneous development of the brain and face, guided by molecular signaling, we examined the relationship of actionable and incidental (non-actionable) MRI findings and NDD diagnoses together with facial morphological variants and genetic copy number variants (CNVs). A cross-sectional study was conducted with a twin cohort 8–36 years of age (57% monozygotic, 40% dizygotic), including 372 subjects (46% with NDDs; 47% female) imaged by MRI, 280 with data for facial morphological variants, and 183 for CNVs. Fifty-one percent of participants had MRI findings. Males had a statistically significantly higher percentage of MRI findings (57.7%) compared with females (43.8%, p = 0.03). Twin zygosity was not statistically significantly correlated with incidence or severity of specific MRI findings. No statistically significant association was found between MRI findings and any NDD diagnosis or facial morphological variants; however, MRI findings were statistically significantly associated with the number of CNVs (OR 1.20, 95% CI 1.00–1.44, p = 0.05, adjusted OR for sex 1.24, 95% CI 1.03–1.50, p = 0.02). When combining the presence of MRI findings, facial morphological variants, and CNVs, statistically significant relationships were found with ASD and ADHD diagnoses (p = 0.0006 and p = 0.002, respectively). The results of this study demonstrate that the ability to identify NDDs from combined radiology, morphology, and CNV assessments may be possible. Additionally, twins do not appear to be at increased risk for neuroradiological variants.


2013 ◽  
Vol 14 (1) ◽  
pp. 76 ◽  
Author(s):  
Stèphan Kraai ◽  
Lilly M Verhagen ◽  
Enrique Valladares ◽  
Joaquin Goecke ◽  
Lorena Rasquin ◽  
...  

2019 ◽  
Vol 21 (1) ◽  
Author(s):  
Ying-Qian Mo ◽  
Ze-Hong Yang ◽  
Jun-Wei Wang ◽  
Qian-Hua Li ◽  
Xin-Yun Du ◽  
...  

Abstract Background Bilateral hands including proximal interphalangeal joints (PIPJs) are recommended on physical, X-ray radiographic, or ultrasonographic examination by clinical guidelines of rheumatoid arthritis (RA), but MRI still tends to examine unilateral wrists and/or MCPJs. We aimed to demonstrate the advantages of MRI examination on bilateral hands including PIPJs for disease assessment in early RA patients. Methods Active early RA patients received 3.0T whole-body MRI examination with contrast-enhanced imaging on bilateral wrists, MCPJs, and PIPJs. MRI features were scored referring to the updated RAMRIS. Clinical assessments were conducted on the day of MRI examination. Results The mean time of MRI examination was 24 ± 3 min. MRI bone erosion in MCPJs would be missed-diagnosed in 23% of patients if non-dominant MCPJs were scanned unilaterally, while osteitis in MCPJs would be missed-diagnosed in 16% of patients if dominant MCPJs were scanned unilaterally. MRI synovitis severity was also asymmetric: 21% of patients showing severe synovitis unilaterally in non-dominant MCPJs/PIPJs and other 20% showing severe synovitis unilaterally in dominant MCPJs/PIPJs. Among these early RA patients, MRI tenosynovitis occurred the most frequently in wrist extensor compartment I, while MRI examination on bilateral hands demonstrated no overuse influence present. However, overuse should be considered in dominant PIPJ2, PIPJ4, and IPJ of thumb of which MRI tenosynovitis prevalence was respectively 18%, 17%, or 16% higher than the non-dominant counterparts. Early MRI abnormality of nervus medianus secondary to severe tenosynovitis occurred either in dominant or non-dominant wrists; MRI of unilateral hands would take a risk of missed-diagnosis. Common MRI findings in PIPJs were synovitis and tenosynovitis, respectively in 87% and 69% of patients. MRI tenosynovitis prevalence in IPJ of thumb or PIPJ5 was much higher than the continued wrist flexor compartments. MRI synovitis or tenosynovitis in PIPJs independently increased more than twice probability of joint tenderness (OR = 2.09 or 2.83, both p < 0.001). Conclusions In consideration of asymmetric MRI features in early RA, potential overuse influence for certain tenosynovitis in dominant hands, and high prevalence of MRI findings in PIPJs, MRI examination on bilateral hands including PIPJs is deserved for disease assessment in early RA patients.


2021 ◽  
Author(s):  
Yonathan Gebrewold ◽  
Bati Tesfaye

Abstract Background: Low back pain (LBP) has become one of the most serious public health problems with substantial socioeconomic implication. Degenerative disc disease one of the commonest cause of LBP. Magnetic resonance imaging (MRI) is routinely utilized in evaluation patients with degenerative changes of the lumbar spine. However there are contradictors reports with regards to association of MRI findings of lumbar spine and patients’ symptoms.Objective: This study is aimed determine correlation of degree of disability with lumbar spine MRI findings in patients with LBP at University of Gondar comprehensive Specialized Hospital (UoGCSH), North West Ethiopia, 2020.Methods and Materials. A prospective cross-sectional study was conducted on 72 consecutively enrolled patients with lower back pain who underwent lumbar MRI scan. Degree of disability was measured using Oswestry disability Index (ODI) questionnaire translated to local language. Association between lumbar spine MRI parameters and ODI score and category was tested using Spearman’s rank correlation coefficient and Chi square tests. Results The mean age the study subjects was 43.81±1.88 years (range 22-83 years). 59.7% of the study population were Female. In terms of ODI category, most fell under minimal and moderate disability 33 (45.8%) and 25(34.7%) respectively. Disc bulge (81.9%) and foraminal stenosis were the most frequent MRI abnormalities detected. ODI score showed weak correlation with grade of spinal canal stenosis. Foraminal stenosis grade was not correlated ODI.Conclusion: The clinical relevance of MRI findings in patients with degenerative disc disease is limited and MRI should be sparingly ordered in evaluation of these patients particularly in resource constrained settings.


2020 ◽  
Vol 27 (10) ◽  
pp. 2129-2132
Author(s):  
Muhammad Zubair ◽  
Mohsin Ur Rashid ◽  
Muhammad Azam ◽  
Hassan Tariq ◽  
Syed Salman Ali ◽  
...  

Objectives: This study was performed to determine the prevalence of Hepatitis B and C virus in general population of Rahim Yar Khan. Study Design: Cross Sectional and Observational study. Setting: Combined Military Hospital Rahim Yar Khan. Period: 1st Jan 2018 to 30th June 2019. Material & Methods: Patients of both genders and all ages were included in the study. HBV and HCV were analysed using Kit method and positive cases confirmed by ELISA. Results: A total number of 4635 people were screened for Hepatitis B, and C. Among 2325 individuals screened for HCV, 365 (15.6%) were positive for Anti HCV. Among 2310 individuals screened for HBV, 82 (3.5%) were found positive. Positive cases were later confirmed by ELISA. Conclusion: High prevalence of HBV and HCV in this area warrants serious efforts to prevent the spread of these viruses. Screening facilities should be provided at community level to assess the real burden and for early diagnosis and prevention of complications.


2014 ◽  
Vol 6 (2) ◽  
Author(s):  
Christy N. Mintjelungan

Abstract: Dental caries is a disease of dental hard tissue characterised by demineralization of the inorganic substances and dissolving of the organic substances. The prevalence of dental caries in pre-school children is still high which may due to the improper way of teeth brushing as well as consuming cariogenic foods. This study aimed to determine the prevalence of dental decidious caries status among pre-school children in Malalayang district, Manado. This was a descriptive observational study with a cross-sectional approach. This study was carried out in July 2012. The data were obtained by using questionnaires and observation. The population in this study was all kindergarten pupils (788 children) in Malalayang district and the number of samples were 90 children. Data were obtained from primary and secondary data. The results showed that the prevalence of dental caries was 90% with the average index def-t = 6.99. Conclusion: There was a very high prevalence of dental caries among kindergarten pupils in Malalayang district, Manado. Keywords: prevalence, dental decidious caries, pre-school children.     Abstrak: Karies gigi adalah penyakit jaringan keras gigi yang ditandai dengan terjadinya demineralisasi substansi anorganik dan penghancuran substansi organik. Prevalensi karies gigi anak usia prasekolah yang masih tinggi disebabkan antara lain kebiasaan menyikat gigi yang tidak sesuai prosedur serta kegemaran mengonsumsi makanan kariogenik. Penelitian ini bertujuan untuk mengetahui prevalensi karies gigi sulung pada anak prasekolah di kecamatan Malalayang kota Manado. Metode penelitian yang digunakan ialah deskriptif observasional dengan pendekatan potong lintang. Penelitian ini dilakukan pada bulan Juli 2012. Pengumpulan data dilakukan dengan kuesioner dan observasi. Populasi penelitian yaitu seluruh murid Taman Kanak-kanak di kecamatan Malalayang yang berjumlah 788 anak. Sampel yang diambil sebanyak 90 anak.  Data penelitian ini diperoleh dari data primer dan sekunder. Hasil penelitian menunjukkan bahwa prevalensi karies gigi sulung sebesar 90% dengan indeks  rata-rata def-t = 6,99 yang berarti rata-rata setiap anak memiliki 7 gigi yang mengalami karies. Simpulan: Prevalensi kareis gigi sulung pada murid Taman Kanak-kanak di kecamatan Malalayang kota Manado tergolong sangat tinggi. Kata kunci: prevalensi, karies gigi sulung, anak prasekolah.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Noor Shaikh ◽  
Honglin Zhang ◽  
Stephen H. M. Brown ◽  
Hamza Lari ◽  
Oliver Lasry ◽  
...  

AbstractThis study investigated feasibility of imaging lumbopelvic musculature and geometry in tandem using upright magnetic resonance imaging (MRI) in asymptomatic adults, and explored the effect of pelvic retroversion on lumbopelvic musculature and geometry. Six asymptomatic volunteers were imaged (0.5 T upright MRI) in 4 postures: standing, standing pelvic retroversion, standing 30° flexion, and supine. Measures included muscle morphometry [cross-sectional area (CSA), circularity, radius, and angle] of the gluteus and iliopsoas, and pelvic geometry [pelvic tilt (PT), pelvic incidence (PI), sacral slope (SS), L3–S1 lumbar lordosis (LL)] L3-coccyx. With four volunteers repeating postures, and three raters assessing repeatability, there was generally good repeatability [ICC(3,1) 0.80–0.97]. Retroversion had level dependent effects on muscle measures, for example gluteus CSA and circularity increased (up to 22%). Retroversion increased PT, decreased SS, and decreased L3–S1 LL, but did not affect PI. Gluteus CSA and circularity also had level-specific correlations with PT, SS, and L3–S1 LL. Overall, upright MRI of the lumbopelvic musculature is feasible with good reproducibility, and the morphometry of the involved muscles significantly changes with posture. This finding has the potential to be used for clinical consideration in designing and performing future studies with greater number of healthy subjects and patients.


2018 ◽  
Vol 08 (02) ◽  
pp. 114-116
Author(s):  
Muhammad Shahrukh Khan Sadiq ◽  
Moona Mumtaz ◽  
Syed Abrar Ali ◽  
Jouhrah Hussain Khan ◽  
Syed Ahmed Omer ◽  
...  

Objective: Oral pathological findings are often associated with diabetes mellitus. The aim of the study was to assess the frequency of oral findings among diabetic patients of both genders. Materials and Methods: A cross-sectional observational study was conducted from February 2017 to November 2017 at Bahria University Dental Hospital & Mamji Hospital, Karachi. A total of 363 diagnosed patients of diabetes mellitus were selected for the study. A questionnaire was designed and oral clinical examination was performed. The collected data was analyzed by using SPSS version 23. Results: A total number of 363 diagnosed patients of diabetes mellitus were included in the study. Among these 187 (51.52%) were male and 176 (48.48%) were female. The overall oral mucosal findings were predominantly present in male diabetic patients as compared to females. Conclusion: The result of this study showed a high prevalence of oral pathological findings in diabetic patients


2017 ◽  
Vol 256 ◽  
pp. S47
Author(s):  
Mihai Savescu ◽  
Alexandru Gabriel Neagu ◽  
Constantin Vlagioiu ◽  
Niculae Tudor ◽  
Gabriel Predoi ◽  
...  

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