Proliferation arrest, selectivity, and chemosensitivity enhancement of cancer cells treated by a low-intensity alternating electric field

2018 ◽  
Vol 20 (4) ◽  
Author(s):  
Kin Fong Lei ◽  
Shao-Chieh Hsieh ◽  
Andrew Goh ◽  
Rei-Lin Kuo ◽  
Ngan-Ming Tsang
2019 ◽  
Vol 9 (3) ◽  
pp. 344-352 ◽  
Author(s):  
L.I. Stefanovich ◽  
O.Y. Mazur ◽  
V.V. Sobolev

Introduction: Within the framework of the phenomenological theory of phase transitions of the second kind of Ginzburg-Landau, the kinetics of ordering of a rapidly quenched highly nonequilibrium domain structure is considered using the lithium tantalate and lithium niobate crystals as an example. Experimental: Using the statistical approach, evolution equations describing the formation of the domain structure under the influence of a high-frequency alternating electric field in the form of a standing wave were obtained. Numerical analysis has shown the possibility of forming thermodynamically stable mono- and polydomain structures. It turned out that the process of relaxation of the system to the state of thermodynamic equilibrium can proceed directly or with the formation of intermediate quasi-stationary polydomain asymmetric phases. Results: It is shown that the formation of Regular Domain Structures (RDS) is of a threshold character and occurs under the influence of an alternating electric field with an amplitude less than the critical value, whose value depends on the field frequency. The conditions for the formation of RDSs with a micrometer spatial scale were determined. Conclusion: As shown by numerical studies, the RDSs obtained retain their stability, i.e. do not disappear even after turning off the external electric field. Qualitative analysis using lithium niobate crystals as an example has shown the possibility of RDSs formation in high-frequency fields with small amplitude under resonance conditions


2001 ◽  
Vol 32 ◽  
pp. 951-952
Author(s):  
M. LACKOWSKI ◽  
A. JAWOREK ◽  
A. KRUPA

1946 ◽  
Vol 19 (4) ◽  
pp. 1085-1087
Author(s):  
Pierre Girard ◽  
Paul Abadie

Abstract The spectra which were studied lie within the region of hertzian frequencies, and can be represented either by dispersion curves showing the dielectric constant of the substance as a function of the frequency (or wave length λ), or by absorption curves showing the loss angle as a function of this frequency. These two types of curves represent the same phenomenon, i.e., orientation of the dipolar molecules in the alternating electric field, in accordance with the theory of Debye. The spectra and their interpretation depend chiefly on whether the molecules are crystalloid with relatively small and similar dimensions, or are colloidal, with large and unequal dimensions. In the first case, the spectra gives evidence chiefly on the form of the molecules and their structural features. Dilution in a nonpolar solvent shows for certain dipolar compounds, e.g., alcohol, considerable deformations, which differ according to the solvent. In the case of colloids, e.g., rubber, which has a permanent moment, the spectra and the meaning of these spectra are far different. In this case the spectra indicate that the absorption and dispersion values in the hertzian region are closely related to the micellar constitution, i.e., to the different types of micelles, to their size, and to the proportion of each type.


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