Left bundle branch block without a typical contraction pattern is associated with increased risk of ventricular arrhythmias in cardiac resynchronization therapy patients

Author(s):  
Shema Bouazzi ◽  
Bhupendar Tayal ◽  
Thomas Fritz Hansen ◽  
Michael Vinther ◽  
Joseph Kisslo ◽  
...  
2018 ◽  
Vol 90 (12) ◽  
pp. 76-83 ◽  
Author(s):  
S Yu Kashtanova ◽  
N A Mironova ◽  
V N Shitov ◽  
E M Gupalo ◽  
V G Kiktev ◽  
...  

Aim. To assess the value of the complex analysis of electrocardiographic (ECG) variants and echocardiographic (echo) manifestation of left bundle branch block (LBBB) in predicting the success of cardiac resynchronization therapy (CRT). Materials and methods. The study included 39 patients (mean age 61.49±9.0 years) on sinus rhythm with LBBB, QRS duration ≥130 ms, left ventricular ejection fraction (LVEF) ≤35%, heart failure (HF) NYHA II-IV despite optimal pharmacological therapy during 3 month. All patients had undergone CRT-D implantation. Depending on presence or absence of ECG-criteria, proposed by D.G. Strauss et al., patients were divided into 2 groups: 1 group - strict LBBB, proposed by D.G. Strauss et al. (n=29) and 2 group - other patients (n=10). In addition to standard echocardiography, global longitudinal 2-dimensional strain (GLS) and LBBB contraction pattern have been performed initially and in 6 months after implantation. Response to CRT was defined as decrease in LV end-systolic volume by >15% after 6 months of follow-up. Results and discussion. Typical LBBB echo contraction pattern was detected in 25 patients (64% of all included). These patients had more pronounced longitudinal dissynchrony and a more expressed global longitudinal strain before CPT-D implantation (p


2018 ◽  
Vol 269 ◽  
pp. 165-169 ◽  
Author(s):  
Maria Luce Caputo ◽  
Antonius van Stipdonk ◽  
Annekatrin Illner ◽  
Gabriele D'Ambrosio ◽  
François Regoli ◽  
...  

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