Is Ulcerative Colitis Associated with Survival Among Older Persons with Colorectal Cancer in the US? A Population-Based Case–Control Study

2011 ◽  
Vol 57 (6) ◽  
pp. 1647-1651 ◽  
Author(s):  
Aasma Shaukat ◽  
Nadim I. Salfiti ◽  
Daniel J. Virnig ◽  
David H. Howard ◽  
Shanthi V. Sitaraman ◽  
...  
Gut ◽  
1998 ◽  
Vol 42 (5) ◽  
pp. 711-714 ◽  
Author(s):  
P Karlén ◽  
D Kornfeld ◽  
O Broström ◽  
R Löfberg ◽  
P-G Persson ◽  
...  

Background—Colonoscopic surveillance is a standard procedure in many patients with long standing, extensive ulcerative colitis (UC), in order to avoid death from colorectal cancer. No conclusive proof of its benefits has been presented however.Aims—To evaluate the association between colonoscopic surveillance and colorectal cancer mortality in patients with UC.Patients—A population based, nested case control study comprising 142 patients with a definite UC diagnosis, derived from a study population of 4664 patients with UC, was conducted.Methods—Colonoscopic surveillance in all patients with UC who had died from colorectal cancer after 1975 was compared with that in controls matched for age, sex, extent, and duration of the disease. Information on colonoscopic surveillance was obtained from the medical records.Results—Two of 40 patients with UC and 18 of 102 controls had undergone at least one surveillance colonoscopy (relative risk (RR) 0.29, 95% confidence interval 0.06 to 1.31). Twelve controls but only one patient with UC had undergone two or more surveillance colonoscopies (RR 0.22, 95% confidence interval 0.03 to 1.74), indicating a protective dose response relation.Conclusion—Colonoscopic surveillance may be associated with a decreased risk of death from colorectal cancer in patients with long standing UC.


Endoscopy ◽  
2006 ◽  
Vol 37 (12) ◽  
Author(s):  
L Sharp ◽  
LF Masson ◽  
J Little ◽  
NT Brockton ◽  
SC Cotton ◽  
...  

1998 ◽  
Vol 115 (5) ◽  
pp. 1079-1083 ◽  
Author(s):  
K NUAKO ◽  
D AHLQUIST ◽  
D MAHONEY ◽  
D SCHAID ◽  
D SIEMS ◽  
...  

2014 ◽  
Vol 71 (Suppl 1) ◽  
pp. A5.3-A6 ◽  
Author(s):  
Kyriaki Papantoniou ◽  
Manolis Kogevinas ◽  
Vicente Martin Sanchez ◽  
Victor Moreno ◽  
Marina Pollan ◽  
...  

2019 ◽  
Vol 50 (3) ◽  
pp. 295-305 ◽  
Author(s):  
Antonio Rodríguez-Miguel ◽  
Luis A. García-Rodríguez ◽  
Miguel Gil ◽  
Diana Barreira-Hernández ◽  
Sara Rodríguez-Martín ◽  
...  

In Vivo ◽  
2019 ◽  
Vol 33 (2) ◽  
pp. 573-579 ◽  
Author(s):  
CHIA-LING LIN ◽  
TA-CHUN LIU ◽  
YA-NI WANG ◽  
CHI-HSIANG CHUNG ◽  
WU-CHIEN CHIEN

2006 ◽  
Vol 130 (7) ◽  
pp. 1941-1949 ◽  
Author(s):  
Fernando S. Velayos ◽  
Edward V. Loftus ◽  
Tine Jess ◽  
W. Scott Harmsen ◽  
John Bida ◽  
...  

2018 ◽  
Vol 75 (5) ◽  
pp. 344-350 ◽  
Author(s):  
Wa Mwenga Walasa ◽  
Renee N Carey ◽  
Si Si ◽  
Lin Fritschi ◽  
Jane S Heyworth ◽  
...  

ObjectiveResearch indicates that shiftwork may be associated with increased risks of adverse health outcomes, including some cancers. However, the evidence of an association between shiftwork and colorectal cancer risk is limited and inconclusive. Further, while several possible pathways through which shiftwork might result in cancer have been proposed, few studies have taken these factors into account. We investigated the association between two types of shiftwork (graveyard shiftwork and early-morning shiftwork) and six mechanistic shiftwork variables (including light at night and phase shift) and the risk of colorectal cancer among females in an Australian population-based case–control study. Graveyard shiftwork was the primary exposure of interest.MethodsParticipants (350 cases and 410 controls) completed a lifetime occupational history, and exposure to each of the eight shiftwork variables was assigned to participants through a job exposure matrix. We used logistic regression to calculate odds ratios (OR) and corresponding 95% confidence intervals (CI) for the association between different shiftwork variables and the risk of colorectal cancer, adjusting for potential demographic, lifestyle and medical confounders.ResultsWorking in an occupation involving long-term exposure (>7.5 years) to graveyard shiftwork was not associated with colorectal cancer risk (adjusted OR 0.95, 95% CI 0.57 to 1.58). Similarly, no increased risks of colorectal cancer were seen for any of the other seven shiftwork variables examined.ConclusionsNo evidence of an increased risk of colorectal cancer among females who had worked in occupations involving shiftwork was observed in this study.


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