scholarly journals Sustainable use of CRISPR/Cas in fish aquaculture: the biosafety perspective

Author(s):  
Arinze S. Okoli ◽  
Torill Blix ◽  
Anne I. Myhr ◽  
Wenteng Xu ◽  
Xiaodong Xu

AbstractAquaculture is becoming the primary source of seafood for human diets, and farmed fish aquaculture is one of its fastest growing sectors. The industry currently faces several challenges including infectious and parasitic diseases, reduced viability, fertility reduction, slow growth, escapee fish and environmental pollution. The commercialization of the growth-enhanced AquAdvantage salmon and the CRISPR/Cas9-developed tilapia (Oreochromis niloticus) proffers genetic engineering and genome editing tools, e.g. CRISPR/Cas, as potential solutions to these challenges. Future traits being developed in different fish species include disease resistance, sterility, and enhanced growth. Despite these notable advances, off-target effect and non-clarification of trait-related genes among other technical challenges hinder full realization of CRISPR/Cas potentials in fish breeding. In addition, current regulatory and risk assessment frameworks are not fit-for purpose regarding the challenges of CRISPR/Cas notwithstanding that public and regulatory acceptance are key to commercialization of products of the new technology. In this study, we discuss how CRISPR/Cas can be used to overcome some of these limitations focusing on diseases and environmental release in farmed fish aquaculture. We further present technical limitations, regulatory and risk assessment challenges of the use of CRISPR/Cas, and proffer research strategies that will provide much-needed data for regulatory decisions, risk assessments, increased public awareness and sustainable applications of CRISPR/Cas in fish aquaculture with emphasis on Atlantic salmon (Salmo salar) breeding.

2017 ◽  
Vol 16 (2) ◽  
pp. 41-54 ◽  
Author(s):  
Peter Joyce

Purpose The purpose of this paper is to analyse the 2016 elections for Police and Crime Commissioners (PCCs) and to compare them with those that took place in 2012. It seeks to evaluate the background of the candidates who stood for office in 2016, the policies that they put forward, the results of the contests and the implications of the 2016 experience for future PCC elections. Design/methodology/approach This paper is based around several key themes – the profile of candidates who stood for election, preparations conducted prior to the contests taking place, the election campaign and issues raised during the contests, the results and the profile of elected candidates. The paper is based upon documentary research, making particular use of primary source material. Findings The research establishes that affiliation to a political party became the main route for successful candidates in 2016 and that local issues related to low-level criminality will dominate the future policing agenda. It establishes that although turnout was higher than in 2012, it remains low and that further consideration needs to be devoted to initiatives to address this for future PCC election contests. Research limitations/implications The research focusses on the 2016 elections and identifies a number of key issues that emerged during the campaign affecting the conduct of the contests which have a bearing on future PCC elections. It treats these elections as a bespoke topic and does not seek to place them within the broader context of the development of the office of PCC. Practical implications The research suggests that in order to boost voter participation in future PCC election contests, PCCs need to consider further means to advertise the importance of the role they perform and that the government should play a larger financial role in funding publicity for these elections and consider changing the method of election. Social implications The rationale for introducing PCCs was to empower the public in each police force area. However, issues that include the enhanced importance of political affiliation as a criteria for election in 2016 and the social unrepresentative nature of those who stood for election and those who secured election to this office in these contests coupled with shortcomings related to public awareness of both the role of PCCs and the timing of election contests threaten to undermine this objective. Originality/value The extensive use of primary source material ensures that the subject matter is original and its interpretation is informed by an academic perspective.


2005 ◽  
Vol 89 (1) ◽  
pp. 42-50 ◽  
Author(s):  
Joyce S. Tsuji ◽  
Andrew D. Maynard ◽  
Paul C. Howard ◽  
John T. James ◽  
Chiu-wing Lam ◽  
...  

2021 ◽  
Vol 6 (2) ◽  
Author(s):  
Alfina Fitri Damayanti ◽  
Nina Aini Mahbubah

Zero accident was considered as the primary occupational health and safety value in manufacturing and service enterprises.  PT. ABC provided  electrical and instrument services, including a low-voltage installation, high-voltage installation and an instrument installation. This company is known to excellent electricity and instrument service providers across the country . Moreover, men’s power is used as a primary source to maintain  these kind  of services. Installation projects depend not only on the high working speed, but also on  high working  accuracy within  certain timeframes . As a result, work  accidents  have occurred with a classification varying from minor to fatal accidents.  The purpose of this research is to identify potential hazards to assess risk levels and  obtain recommendations for  preventing accident. The HIRARC method is employed as a research approach. This research is initiated through Hazard Identification, Risk Assessment and Risk Control.  This research identified that two hazards were classified as  extreme risk, three hazards as high- risk, eight hazards as moderate risk , and two hazards have been identified as low risk . Furthermore, a number of action lists have been suggested in order to minimize accident rates and finally the working conditions are designed to maintain zero accidents.


1991 ◽  
Vol 44 (1) ◽  
pp. 30-36
Author(s):  
Fraser MacLeod

Agriculture in the U.K. has, since the late 1940s, enjoyed government subsidy and insulation from free market forces. However, the post-war philosophy of ‘every acre counts’ no longer holds true in the face of surplus production and a growing public awareness of the countryside and environmental issues. Legislation relating to water pollution, public rights of way and price support mechanisms are all contributory factors to the radical changes which agriculture is undergoing at the present time. Investigations have shown a need within agriculture for the efficient use and handling of data relating to the land, and a need for new technology to exploit the inherent spatial variability of, for example, the soil. This paper will discuss the development of an agricultural vehicle positioning instrument and future research which will address the needs which have been identified.


Author(s):  
Muhammad Syafiq N ◽  
◽  
Shaharuddin MS ◽  
Zaenal Abidin ◽  
◽  
...  

ABSTRACT Introduction: Contamination of nitrate is one of the most common groundwater problems worldwide. Around 70% of residents in the state of Kelantan still rely on groundwater as their primary source of water supply. Extensive usage of fertilizer in agricultural areas may cause nitrate leaching into the groundwater. This study aimed to determine the level of nitrate in groundwater and health risk assessment at three villages in Tanah Merah District, Kelantan, Malaysia. Subjects and Method: This was a cross-sectional study conducted at Tanah Merah district, Kelantan, in January 2020. A total of 52 residents was selected by purposive sampling. The inclusion criteria for study subjects were long life residents, age ≥18 years old, and groundwater as a primary source of drinking supply. The study variables were (1) Level of nitrate in groundwater measured according to age (year), depth (meter), and distance (meter) of well from the agricultural area; and (2) Health risk assessment measured by hazard quotient (HQ). A set of questionnaires consisted of four sections to gather information related to socio-demographic, water usage, living environment, and health status. Groundwater samples were collected in duplicates and were analysed using a Hanna Instruments portable pH/ORP/ISE meter with an attached nitrate electrode. The data were reported descriptively. Results: Nitrate levels were found to be under the maximum acceptable value of 10 mg/L, as stated by the Drinking Water Quality Standard of Malaysia. Nitrate level ranged from 0.22 to 8.81 mg/L (Mean= 2.94; SD= 2.27). Spearman rho correlation showed that nitrate level was significantly and negatively correlated the age of wells (r= -0.31; p= 0.025). Nitrate level was not significantly correlated with the depth (r= 0.19; p= 0.183) and distance of wells (r= -0.05; p= 0.751). Hazard quotient (HQ) for all study subjects was <1, which means that exposure to nitrate contained drinking water in study subjects was not detrimental to health. Conclusion: Nitrate levels were below the maximum acceptable value, but continuous monitoring from health authorities is essential since other seasons of paddy planting may contribute higher deposition of nitrate into groundwater. Keywords: nitrate, groundwater, levels, hazard quotient, Tanah Merah Correspondence: Muhammad Syafiq N. Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia. UPM Serdang, Selangor, Malaysia. Email: [email protected]. Mobile: +601140731881. DOI: https://doi.org/10.26911/the7thicph.01.27


2013 ◽  
pp. 1667-1681 ◽  
Author(s):  
Morshed U. Chowdhury ◽  
Biplob R. Ray

Remote technologies are changing our way of life. The radio frequency identification (RFID) system is a new technology which uses the open air to transmit information. This information transmission needs to be protected to provide user safety and privacy. Business will look for a system that has fraud resilience to prevent the misuse of information to take dishonest advantage. The business and the user need to be assured that the transmitted information has no content which is capable of undertaking malicious activities. Public awareness of RFID security will help users and organizations to understand the need for security protection. Publishing a security guideline from the regulating body and monitoring implementation of that guideline in RFID systems will ensure that businesses and users are protected. This chapter explains the importance of security in a RFID system and will outline the protective measures. It also points out the research direction of RFID systems.


Author(s):  
Morshed U. Chowdhury ◽  
Biplob R. Ray

Remote technologies are changing our way of life. The radio frequency identification (RFID) system is a new technology which uses the open air to transmit information. This information transmission needs to be protected to provide user safety and privacy. Business will look for a system that has fraud resilience to prevent the misuse of information to take dishonest advantage. The business and the user need to be assured that the transmitted information has no content which is capable of undertaking malicious activities. Public awareness of RFID security will help users and organizations to understand the need for security protection. Publishing a security guideline from the regulating body and monitoring implementation of that guideline in RFID systems will ensure that businesses and users are protected. This chapter explains the importance of security in a RFID system and will outline the protective measures. It also points out the research direction of RFID systems.


Author(s):  
Maurice Strong

To environmentalists the concept of globalism is not new. Indeed the environmental movement is based on the realization that the environment and natural resources of the earth, which nourish and sustain life on our planet, are systemic in nature and intrinsically global in scale. Thus environmentalists tend to perceive even the most local of conditions as being linked to the complex system of cause and effect relationships on which the health of the environment of our planet as a whole depends. The processes through which human activity impacts on, and interacts with, this global system have accelerated to an unprecedented degree during the past century through the phenomenon we now call globalization. This can be seen by environmentalists as a mixed blessing. On one hand, it has vastly increased public awareness of the global nature of environmental issues and provided the impetus for international actions to deal with them. On the other hand, globalization has been driven largely by economic motivations which have served to accelerate the environmental deterioration that we have witnessed during this last century, particularly the latter part of it, and which continue to undermine the earth’s natural capital. Knowledge is clearly the principal resource on which the future growth, development and governance of our civilization will be based. Technology manifested in a galaxy of new products and services, design, management and information systems is the primary source of added value and comparative advantage in the global economy (Castells, this volume). It also offers the main ingredient for the transition to sustainability through patterns of production and consumption that are less physical in nature, and less materials- and energy-intensive. The value of a compact disk or a computer chip is primarily attributable to the functions and characteristics with which human intelligence and technology have endowed it, rather than to its material content. This dematerialization of economic growth is already evident in the fact that the biggest single export of the United States today, amounting to some $30 billion per year, is entertainment.


Author(s):  
Sunil Chaudhary ◽  
Eleni Berki ◽  
Linfeng Li ◽  
Juri Valtanen

Public awareness is a significant factor in the battle against online identity theft (phishing). Advancing public readiness can be a strategic protection mechanism for citizens' vulnerability and privacy. Further, an effective research strategy against phishing is the combination of increased social awareness with software quality and social computing. The latter will decrease phishing victims and will improve information systems quality. First, the authors discuss recent research results on software quality criteria used for the design of anti-phishing technologies. Second, it is argued that the dynamics of social surroundings affect citizens' trust and can compromise social security. Third, the authors outline basic research needs and strategic steps to be taken for timely citizens' protection. Last, the authors propose strategic research directions for improving information systems total quality management through international collaborative research and by focusing on: i) increasing social awareness; ii) predicting information phishing attempts; iii) adopting social computing approaches.


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