scholarly journals Quantifiable urine glyphosate levels detected in 99% of the French population, with higher values in men, in younger people, and in farmers

2022 ◽  
Author(s):  
Daniel Grau ◽  
Nicole Grau ◽  
Quentin Gascuel ◽  
Christian Paroissin ◽  
Cécile Stratonovitch ◽  
...  
Keyword(s):  
Occupational Exposure ◽  
General Population ◽  
Dietary Habits ◽  
Urine Samples ◽  
French Population ◽  
Industrialized Countries ◽  
Food And Water Intake ◽  
Growing Environment ◽  
Consuming Country ◽  
Single Laboratory

Abstract France is the first pesticide-consuming country in Europe. Glyphosate is the most used pesticide worldwide and glyphosate is detected in the general population of industrialized countries, with higher levels found in farmers and children. Little data was available concerning exposure in France. Our objective was to determine glyphosate levels in the French general population and to search for an association with seasons, biological features, lifestyle status, dietary habits, and occupational exposure. This study includes 6848 participants recruited between 2018 and 2020. Associated data include age, gender, location, employment status, and dietary information. Glyphosate was quantified by a single laboratory in first-void urine samples using ELISA. Our results support a general contamination of the French population, with glyphosate quantifiable in 99.8% of urine samples with a mean of 1.19 ng/ml + / − 0.84 after adjustment to body mass index (BMI). We confirm higher glyphosate levels in men and children. Our results support glyphosate contamination through food and water intake, as lower glyphosate levels are associated with dominant organic food intake and filtered water. Higher occupational exposure is confirmed in farmers and farmers working in wine-growing environment. Thus, our present results show a general contamination of the French population with glyphosate, and further contribute to the description of a widespread contamination in industrialized countries.

scholarly journals Associations between Perceived Social Eating Norms and Initiation and Maintenance of Changes in Dietary Habits during the First COVID-19 Lockdown in France

Foods ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 2745
Author(s):  
Armelle Garcia ◽  
Suzanne Higgs ◽  
Anne Lluch ◽  
Nicolas Darcel ◽  
Olga Davidenko
Keyword(s):  
General Population ◽  
Dietary Habits ◽  
French Population ◽  
Positive Perception ◽  
Dietary Changes ◽  
Online Study ◽  
Social Eating ◽  
Household Members ◽  
Lasting Influence

Changes in dietary habits of the French population have been reported during the national lockdown that was enforced due to the COVID-19 pandemic. This study investigated whether perceived social eating norms were associated with the initiation and maintenance of dietary changes that took place as a result of lockdown. An online study collected information on (1) changes in consumption implemented during the lockdown and the maintenance of these changes, and (2) perceptions about changes in consumption implemented during lockdown by household members, relatives out of home, and the general population. The changes in consumption were classified as foods to increase or to decrease according to French national recommendations. The perception of changes to dietary habits by household members and relatives out of home was related to the changes made by individuals for each of the food categories (all p < 0.05) but not to the perception of changes made the general population. Increased consumption of foods to increase was more likely to be maintained when there was a positive perception of the changes made by household members (p = 0.03). These results highlight the influence of the perception of social eating norms, especially by household members and relatives, on the implementation of dietary changes during lockdown and suggest that social eating norms can have a lasting influence.

scholarly journals AB0533 ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODY (ANCA) IN GENERAL POPULATION WITHOUT ANCA ASSOCIATED VASCULITIS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1563.3-1563
Author(s):  
H. Tamaki ◽  
S. Fukui ◽  
T. Nakai ◽  
G. Kidoguchi ◽  
S. Kawaai ◽  
...  
Keyword(s):  
Risk Factors ◽  
Autoimmune Disease ◽  
General Population ◽  
Granulomatosis With Polyangiitis ◽  
Dietary Habits ◽  
Laboratory Data ◽  
Clinical Manifestations ◽  
Anca Associated Vasculitis ◽  
The Mean

Background:Currently it is hypothesized that many systemic autoimmune diseases occur due to environmental risk factors in addition to genetic risk factors. Anti-Neutrophil Cytoplasmic Antibody (ANCA) is mainly associated with three systemic autoimmune disease including granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), eosinophilic granulomatosis with polyangiitis (EGPA). It is known that ANCA can be positive before clinical symptoms in patients with known diagnosis of GPA and ANCA titers rise before clinical manifestations appear. However, prevalence of ANCA among general population is not well known. It has not been described as well how many of people with positive ANCA eventually develop clinical manifestations of ANCA associated Vasculitis.Objectives:This study aims to estimate prevalence of ANCA in general population without ANCA associated Vasculitis. It also describes natural disease course of people with positive ANCA without ANCA associated Vasculitis. Risk factors for positive ANCA are also analyzed.Methods:This is a single center retrospective study at Center for Preventive Medicine of St. Luke’s International Hospital in Tokyo. ANCA was checked among the patients who wished to between 2018 and 2019. St. Luke’s Health Check-up Database (SLHCD) was utilized to collect the data. The patients whose serum was measured for ANCA were identified. The data for basic demographics, social habits, dietary habits and laboratory data were extracted. The charts of the patients with positive ANCA were reviewed.Results:Sera of total 1204 people were checked for ANCA. Of these 1204 people, 587 (48.8%) are male and the mean age was 55.8 years (32.6 to 79). There were total 11 patients with positive ANCA. Myeloperoxidase ANCA (MPO-ANCA) was positive for 3 patients and proteinase 3 ANCA (PR3-ANCA) was positive for 8 patients. Of these 11 patients, 5 were male (45.5%) and the mean age was 54.6 years. Two patients had history of autoimmune disease (primary biliary cirrhosis and ulcerative colitis). Five patients were evaluated by rheumatologists with the median follow-up period of 274 days. None of them developed clinical signs and symptoms of ANCA associated Vasculitis. Four out of five patients had ANCA checked later, two of which turned negative. The prevalence of ANCA in this cohort was 0.9% (95% confidence interval [95% CI]: 0.5% to 1.6%). Univariate analysis was performed to identify risk factors of positive ANCA. The variables analyzed include age, gender, body mass index (BMI), smoking habits, alcohol intake, dietary habits (fruits, fish, red meat), hypertension, dyslipidemia, and laboratory data. None of these variables demonstrated statistically significant differences except for positive rheumatoid factor (ANCA positive group: 33 % vs ANCA negative group: 9.1%, p value = 0.044).Conclusion:The prevalence of ANCA in this cohort was 0.9% (95% CI: 0.5% to 1.6%). None of them who had a follow-up developed ANCA associated Vasculitis during the follow-up period. Longer follow-up and more patients are necessary to determine natural course of people with positive ANCA.Disclosure of Interests:None declared

scholarly journals O5D.3 Methods of estimating lifetime occupational exposure in the general population, based on job-exposure matrices

2019 ◽  
Vol 76 (Suppl 1) ◽  
pp. A48.1-A48
Author(s):  
Marie Houot ◽  
Julie Homère ◽  
Hélène Goulard ◽  
Loïc Garras ◽  
Laurène Delabre ◽  
...  
Keyword(s):  
Occupational Exposure ◽  
General Population ◽  
Population Based ◽  
Estimation Methods ◽  
Cement Dust ◽  
Maximum Probability ◽  
Silica Dust ◽  
Weak Points ◽  
Flour Dust ◽  
The Impact

ObjectivesTo estimate proportion of pathologies attributable to occupational exposure, lifetime occupational exposure prevalence (LOEP) and relative risk are necessary. LOEP estimates are commonly used but often estimated with different methods. The method choice and the impact on estimates are rarely discuss in the literature. This study present and discuss the most widely used means of estimating LOEP and their respective impacts on estimates.MethodsA sample of individuals representative of the French population from 2007 was linked with four Matgéné job-exposure matrices: flour dust, cement dust, silica dust and benzene. LOEP and the 95% confidence interval were estimated using five methods: the maximum exposure probability during the career (Method 1), four using individual exposure probabilities, three of which subdivide careers into job-periods (Methods 2–4) and one which subdivides them into job-years (Method 5). To quantify differences between methods, percentage of variation were calculated for prevalence values on Methods 2 to 5 versus Method 1.ResultsFor each agent, LOEP estimated from the maximum probability during the career (Method 1) was consistently lower than prevalence taking account of job-periods or job-years. LOEP on Method 1 for flour dust, cement dust, silica dust and benzene were respectively 4.4%–95% CI [4.0–4.7], 4.3% [3.9–4.6], 6.1% [5.7–6.5] and 3.9% [3.6–4.2]. Percentage of variation ranged from 0% to 25.0% for flour dust, from 11.6% to 55.8% for cement dust, from 11.5% to 49.1% for silica dust and from 0% to 53.8% for benzene.ConclusionsThe present study provides a description of several LOEP estimation methods in the general population based on job-exposure matrices. It specifies the strong and weak points of each of the five chosen methods. For health monitoring purposes, LOEP should be reported as intervals, with low and high estimates obtained on different methods using job-periods (Methods 2–4).

1053 Estimated dietary sodium intake among adults in Korean general population by 24 hour urine samples

2012 ◽  
Vol 30 ◽  
pp. e306
Author(s):  
Moo-Yong Rhee ◽  
Ji-Hyun Kim ◽  
Yong-Seok Kim ◽  
Young-Kwon Kim ◽  
Myoung-Mook Lee ◽  
...  
Keyword(s):  
General Population ◽  
Sodium Intake ◽  
Urine Samples ◽  
Dietary Sodium

scholarly journals Monitoring of Occupational Exposure to Volatile Organohalogen Solvents (VOXs) in Human Urine Samples of Dry-cleaner Workers by TLHS-DAI-GC-ECD Procedure

2011 ◽  
Vol 49 (1) ◽  
pp. 126-132 ◽  
Author(s):  
Irena RUTKIEWICZ ◽  
Natalia JAKUBOWSKA ◽  
Żaneta POLKOWSKA ◽  
Jacek NAMIEŚNIK
Keyword(s):  
Occupational Exposure ◽  
Human Urine ◽  
Urine Samples ◽  
Human Urine Samples

scholarly journals A Comparison of Dietary Habits Between Recreational Runners and a Randomly Selected Adult Population in Slovenia / Primerjava Prehranskih Navad Rekreativnih Tekačev In Naključno Izbranih Odraslih Ljudi V Sloveniji

2015 ◽  
Vol 54 (3) ◽  
pp. 212-221
Author(s):  
Branko Škof ◽  
Nada Rotovnik Kozjek
Keyword(s):  
General Population ◽  
Dietary Habits ◽  
Adult Population ◽  
Population Group ◽  
Food Groups ◽  
Physically Active ◽  
Healthy Nutrition ◽  
Frequent Consumption ◽  
Recreational Runners ◽  
And Performance

Abstract Introduction. The aim of the study was to compare the dietary habits of recreational runners with those of a random sample of the general population. We also wanted to determine the influence of gender, age and sports performance of recreational runners on their basic diet and compliance with recommendations in sports nutrition. Methods. The study population consisted of 1,212 adult Slovenian recreational runners and 774 randomly selected residents of Slovenia between the ages of 18 and 65 years. The data on the dietary habits of our subjects was gathered by means of two questionnaires. The following parameters were evaluated: the type of diet, a food pattern, and the frequency of consumption of individual food groups, the use of dietary supplements, fluid intake, and alcohol consumption. Results. Recreational runners had better compliance with recommendations for healthy nutrition than the general population. This pattern increased with the runner’s age and performance level. Compared to male runners, female runners ate more regularly and had a more frequent consumption of food groups associated with a healthy diet (fruit, vegetables, whole grain foods, and low-fat dairy products). The consumption of simple sugars and use of nutritional supplements by well-trained runners was inadequate with values recommended for physically active individuals. Conclusion. Recreational runners are an exemplary population group that actively seeks to adopt a healthier lifestyle.

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