scholarly journals Ventilation/perfusion SPECT: One more promising resource to fight the medical Hydra

Author(s):  
Alberto Cuocolo ◽  
Mario Petretta
Keyword(s):  
1999 ◽  
Vol 41 (10) ◽  
pp. 652-659 ◽  
Author(s):  
R Riikonen ◽  
I Salonen ◽  
K Partanen ◽  
S Verho

1999 ◽  
Vol 38 (06) ◽  
pp. 172-177
Author(s):  
H. Bailer ◽  
Marianne Gwechenberger ◽  
Martha Pruckmayer ◽  
A. Staudenherz ◽  
G. Kronik ◽  
...  

Summary Aim: The simultaneous computation and display of wall motion and perfusion patterns in a single 3D ventricular model would considerably ease the assessment of ECG-gated Tc-99m-sestamibi SPECT, yet the effect on the accuracy of allocating regional perfusion has so far not been validated. Methods: 3D perfusion mapping (3D Perfusion/Motion Map Software) was compared to the visual assessment of ungated tomographic slices and polar perfusion mapping (Cedars-Sinai PTQ) by correlation analysis and receiver operating characteristics (ROC) analysis at different cut-off levels for coronary stenoses in 50 patients (11 single-, 22 two-, 16 three-vessel disease). Ungated SPECT data were obtained by adding the intervals prior to reconstruction and displaying conventional tomographic slices. All display options were visually assessed in 8 ventricular segments according to a 4-point scoring system and compared to the graded results of coronary angiography. Results: All three display options showed a comparable diagnostic performance for the detection of severe stenoses. The diagnostic gain for the detection of stenoses above 59% was highest for ungated tomographic slices, followed by ungated polar mapping and 3D mapping. Regional assessment revealed a limited performance of 3D mapping in the proximal anterior and distal lateral wall. Polar mapping showed a balanced regional performance. Conclusion: 3D Perfusion mapping provides comparable information to conventional display options with the highest diagnostic strength in severe stenoses. Further improvement of the algorithm is needed in the definition of the valve plane.


Circulation ◽  
1996 ◽  
Vol 93 (5) ◽  
pp. 905-914 ◽  
Author(s):  
Rory Hachamovitch ◽  
Daniel S. Berman ◽  
Hosen Kiat ◽  
Ishac Cohen ◽  
J. Arthur Cabico ◽  
...  

2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Manon Bordonne ◽  
Mohammad B. Chawki ◽  
Pierre-Yves Marie ◽  
Timothée Zaragori ◽  
Véronique Roch ◽  
...  

Abstract Objective The aim of this study was to compare brain perfusion SPECT obtained from a 360° CZT and a conventional Anger camera. Methods The 360° CZT camera utilizing a brain configuration, with 12 detectors surrounding the head, was compared to a 2-head Anger camera for count sensitivity and image quality on 30-min SPECT recordings from a brain phantom and from 99mTc-HMPAO brain perfusion in 2 groups of 21 patients investigated with the CZT and Anger cameras, respectively. Image reconstruction was adjusted according to image contrast for each camera. Results The CZT camera provided more than 2-fold increase in count sensitivity, as compared with the Anger camera, as well as (1) lower sharpness indexes, giving evidence of higher spatial resolution, for both peripheral/central brain structures, with respective median values of 5.2%/3.7% versus 2.4%/1.9% for CZT and Anger camera respectively in patients (p < 0.01), and 8.0%/6.9% versus 6.2%/3.7% on phantom; and (2) higher gray/white matter contrast on peripheral/central structures, with respective ratio median values of 1.56/1.35 versus 1.11/1.20 for CZT and Anger camera respectively in patients (p < 0.05), and 2.57/2.17 versus 1.40/1.12 on phantom; and (3) no change in noise level. Image quality, scored visually by experienced physicians, was also significantly higher on CZT than on the Anger camera (+ 80%, p < 0.01), and all these results were unchanged on the CZT images obtained with only a 15 min recording time. Conclusion The 360° CZT camera provides brain perfusion images of much higher quality than a conventional Anger camera, even with high-speed recordings, thus demonstrating the potential for repositioning brain perfusion SPECT to the forefront of brain imaging.


2018 ◽  
Vol 56 ◽  
pp. 264-265
Author(s):  
G. Serreli ◽  
C. Ghetti ◽  
O. Ortenzia ◽  
C. Cidda ◽  
C. Lazzara ◽  
...  

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