Assessment of antioxidant and cytotoxicity activities against A-549 lung cancer cell line by synthesized reduced graphene oxide nanoparticles mediated by Camellia sinensis

3 Biotech ◽  
2021 ◽  
Vol 11 (12) ◽  
Author(s):  
Farkhunda Fatima ◽  
Hare Ram Singh ◽  
Santosh Kumar Jha
Nanomedicine ◽  
2019 ◽  
Vol 14 (17) ◽  
pp. 2355-2371 ◽  
Author(s):  
Shivani Thoidingjam ◽  
Ashu Bhan Tiku

Aim: Present work was undertaken to fabricate iron oxide nanoparticles (IONPs) using a green approach for increased therapeutic efficacy. Materials & methods: Two types of IONPs were synthesized, one without any coating (IONPUC) and other coated with Phyllanthus emblica (Amla) fruit extract (IONPA). Both the IONPs were characterized using different techniques and therapeutic efficacy was evaluated in A549 human lung cancer cell line. Results: IONPA were smaller in size with better dispersibility compared with IONPUC. They induced increased reactive oxygen species production, higher DNA damage and apoptosis, which resulted in increased toxicity to cancer cells in comparison to IONPUC. Conclusion: Higher uptake of IONPA and active components coating the surface, may be responsible for the increased therapeutic efficacy in cancer cells.


Heliyon ◽  
2020 ◽  
Vol 6 (9) ◽  
pp. e04953 ◽  
Author(s):  
Subrata Das ◽  
Sangharaj Diyali ◽  
Gopal Vinothini ◽  
Balaji Perumalsamy ◽  
Gowdhami Balakrishnan ◽  
...  

2011 ◽  
Vol 31 (10) ◽  
pp. 1091-1095
Author(s):  
Xiao-lin LI ◽  
Yan-fang ZHANG ◽  
Kai TANG ◽  
Ying TANG ◽  
Ruo-bing JIN ◽  
...  

2013 ◽  
Vol 13 (3) ◽  
pp. 414-421 ◽  
Author(s):  
Raquel T. Lima ◽  
Gemma A. Barron ◽  
Joanna A. Grabowska ◽  
Giovanna Bermano ◽  
Simranjeet Kaur ◽  
...  

2021 ◽  
Vol 27 ◽  
pp. 101089
Author(s):  
Kazuo Ohara ◽  
Shintaro Kinoshita ◽  
Jun Ando ◽  
Yoko Azusawa ◽  
Midori Ishii ◽  
...  

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