Betamethasone-valerate/tazarotene

2019 ◽  
Vol 1778 (1) ◽  
pp. 93-93 ◽  
1975 ◽  
Vol 5 (3) ◽  
pp. 285-290 ◽  
Author(s):  
G. J. ARCHER ◽  
A. K. THOMAS ◽  
S. M. HARDING

2014 ◽  
Vol 170 (4) ◽  
pp. 914-921 ◽  
Author(s):  
S.G. Danby ◽  
J. Chittock ◽  
K. Brown ◽  
L.H. Albenali ◽  
M.J. Cork

1987 ◽  
Vol 15 (3) ◽  
pp. 160-166 ◽  
Author(s):  
R. E. Ashton ◽  
M. Catterall ◽  
N. Morley ◽  
G. Fairris ◽  
D. N. Joseph

The efficacy and acceptability of 0.25% and 0.05% desoxymethasone, 0.1% betamethasone valerate and 1% hydrocortisone creams were compared in patients with eczema. A double-blind parallel group multi-centre design was employed in which 96 patients were recruited by four centres. Patients used one cream for a 3-week period and follow-up assessment visits were made at weekly intervals. Efficacy variables were: erythema/redness, scaling, itching and extent of area affected. These variables were assessed by both the investigator and the patient. The 0.25% desoxymethasone was the most effective treatment, producing the greatest degree of improvement in all clinical parameters, hydrocortisone was the least effective and 0.05% desoxymethasone was of intermediate effectiveness. The 0.1% betamethasone produced similar results to 0.25% desoxymethasone for half the assessments; for the other half the results were similar to 0.05% desoxymethasone. No adverse effects were reported during the study. The results are discussed in terms of physical properties of the vehicles and corticosteroid potency.


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