Fundamental Research on the Densification of Alumina Ceramics by Ferrotitanium Slag

2022 ◽  
Author(s):  
Ying Wang ◽  
Baijun Yan ◽  
Yaxiang Zhang ◽  
Tengfei Deng
Keyword(s):  
Alumina Ceramics ◽  
Fundamental Research

Fundamental Research into Thin Films in a Developing Country

1972 ◽  
Vol 30 ◽  
pp. 500-501
Author(s):  
J.A. Eades ◽  
E. Grünbaum
Keyword(s):  
Thin Films ◽  
Growth Process ◽  
Empirical Process ◽  
Nucleation And Growth ◽  
Research Groups ◽  
Film Research ◽  
Fundamental Research ◽  
Controlled Deposition ◽  
The One ◽  
The University

In the last decade and a half, thin film research, particularly research into problems associated with epitaxy, has developed from a simple empirical process of determining the conditions for epitaxy into a complex analytical and experimental study of the nucleation and growth process on the one hand and a technology of very great importance on the other. During this period the thin films group of the University of Chile has studied the epitaxy of metals on metal and insulating substrates. The development of the group, one of the first research groups in physics to be established in the country, has parallelled the increasing complexity of the field.The elaborate techniques and equipment now needed for research into thin films may be illustrated by considering the plant and facilities of this group as characteristic of a good system for the controlled deposition and study of thin films.

IN SEARCH OF KNOWLEDGE IN PHILOSOPHY (Reflections on the book A. M. Starostin “Research Philosophy”. Rostov-on-Don: Rostov State University of Economics, 2019)

2019 ◽  
Vol 86 (3) ◽  
pp. 152-157
Author(s):  
E. V. Zolotuhina-Abolina
Keyword(s):  
State University ◽  
Objective Reality ◽  
Philosophical Reflection ◽  
Interdisciplinary Problems ◽  
Fundamental Research ◽  
Research Philosophy ◽  
Education Culture

In the monograph of Professor A. M. Starostin the notions “philosophical novations” and “research philosophy” was introduced and approved. The author divides the whole array of philosophic research into fundamental and applied – the sphere of philosophical novations. Fundamental and philosophic investigations are directed to the study of the problems of objective reality, thinking, cognition, the truth, freedom and other basic categories. The sphere of fundamental research is slowly changing and it’s development is marked by the outstanding names (Platon, Descartes, Kant, Schopenhauer, Heidegger etc.). As to the sphere of the philosophic innovations, its emergence and development are connected with application of methods of philosophical reflection to the realization of interdisciplinary problems of science, development of political, religious, artistic, ethical trends, which can't be researched only with the help of their own methods. The sphere of philosophic novations develops dynamically and according to its own scales and is twice larger than the sphere of fundamental philosophy.In his monography the author, from the viewpoint of his treating of fundamental and innovative projection of the philosophic knowledge and philosophic methods, analyses contemporary problems of politics, education, culture, science.

Discovery of an Unexpected Similarity in Ligand Binding Between BRD4 and PPARγ

2019 ◽  
Author(s):  
Lina Humbeck ◽  
Jette Pretzel ◽  
Saskia Spitzer ◽  
Oliver Koch
Keyword(s):  
Cancer Therapy ◽  
Drug Targets ◽  
Synergistic Effects ◽  
Complex Structure ◽  
Peroxisome Proliferator ◽  
Resistance Development ◽  
Peroxisome Proliferator Activated Receptor ◽  
Starting Point ◽  
Fundamental Research ◽  
Important Drug

Knowledge about interrelationships between different proteins is crucial in fundamental research for the elucidation of protein networks and pathways. Furthermore, it is especially critical in chemical biology to identify further key regulators of a disease and to take advantage of polypharmacology effects. A comprehensive scaffold-based analysis uncovered an unexpected relationship between bromodomain-containing protein 4 (BRD4) and peroxisome-proliferator activated receptor gamma (PPARγ). They are both important drug targets for cancer therapy and many more important diseases. Both proteins share binding site similarities near a common hydrophobic subpocket which should allow the design of a polypharmacology-based ligand targeting both proteins. Such a dual-BRD4-PPARγ-modulator could show synergistic effects with a higher efficacy or delayed resistance development in, for example, cancer therapy. Thereon, a complex structure of sulfasalazine was obtained that involves two bromodomains and could be a potential starting point for the design of a bivalent BRD4 inhibitor.

Effects of cold isostatic pressing and granule size distribution on the densification of alumina ceramics

2015 ◽  
Vol 57 (6) ◽  
pp. 495-498 ◽  
Author(s):  
Lidija Ćurković ◽  
Marijana Majić Renjo ◽  
Damir Ciglar
Keyword(s):  
Size Distribution ◽  
Cold Isostatic Pressing ◽  
Granule Size ◽  
Alumina Ceramics ◽  
Isostatic Pressing

Fundamental Research on Physical Activity to Improve Health in Children

2018 ◽  
Vol 26 (1) ◽  
pp. 101-109
Author(s):  
Yeon-Oh Han ◽  
Myung Kim ◽  
Tae-Seop Park ◽  
Jae-Hyun Lee
Keyword(s):  
Physical Activity ◽  
Fundamental Research ◽  
Improve Health

Subjectivity as a factor personal and professional development of a police officer

2020 ◽  
Vol 2020 (4) ◽  
pp. 190-197
Author(s):  
Aleksandr Gorelov ◽  
Stanislav Gorelov ◽  
Nikolay Silkin
Keyword(s):  
Law Enforcement ◽  
Interpersonal Relationships ◽  
Traditional Learning ◽  
Deterministic System ◽  
Educational Organizations ◽  
Traditional System ◽  
Self Development ◽  
Fundamental Research ◽  
Internal Affairs

The results of analytical studies of the subject and subjectivity in relation to law enforcement officers based on the academicians Eddy V. Sayko and Anatoly A. Derkach’s fundamental research are presented in the article. Service in the internal Affairs bodies is a deterministic system. It is characterized by huge information flows, extreme neuropsychic and emotional loads, and complex interpersonal relationships. In this regard, increased requirements are imposed on employees of all levels of the law enforcement system. After studying the long-term dynamics of the level of readiness of cadets of educational organizations of the Ministry of internal Affairs of Russia in the framework of self-development, it can be concluded that specialized competencies formed in the classroom according to the traditional system are not transformedinto skills of the highest order. Based on the research, the obvious problem of further improving the methodology of teaching competent actions in the course of performing operational and service tasks in various conditions is revealed. It is reasonable that the traditional learning process involves the development of a specific algorithm of actions in standard situations of operational and service activities, and when introducing various tasks of modeling typical situations, students often cannot complete the task in changing conditions (beyond the standard).

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