Bovine internal mammary artery as a conduit for coronary revascularization: Long-term results

1993 ◽  
Vol 55 (1) ◽  
pp. 120-122 ◽  
Author(s):  
Ian M. Mitchell ◽  
A. Rashid Essop ◽  
Peter J. Scott ◽  
Paul G. Martin ◽  
Nirmal K. Gupta ◽  
...  
Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Sophia Vaina ◽  
Konstantinos Toutouzas ◽  
Chrysoula Patsa ◽  
Eleftherios Tsiamis ◽  
Elli Stefanadi ◽  
...  

Introduction: Coronary artery bypass grafting (CABG) with left internal mammary artery (LIMA) and percutaneous transluminal coronary angioplasty (PCI) with drug eluting stent (DES) implantation are both effective to treat ischemic heart disease. In the current study we evaluated the long term results of the two methods in patients (pts) with isolated proximal left anterior descending artery lesion (pLAD), suffering from chronic stable angina (CSA). Methods: We included 280 pts, 170 with DES implantation and 110 with LIMA grafting. Primary end points were the occurrence of major adverse cardiac events (MACE), defined as: Death, myocardial infarction and target vessel revascularization (TVR). Secondary end-points included the length of hospitalization, in-hospital complications and the recurrence of chest pain. Pts were followed-up clinically. Results: Mean follow-up period was two years (midrange, one to three years). MACE was 5.29% in the DES group and 2.72% in the surgical group (p=0.37). TVR was 3.52% after PCI and 0% after CABG (p=0.08). The event-free survival curve was similar between the two groups (Figure ). More in-hospital complications were observed in the surgical group compared with the PCI group (16.36% vs. 1.17%, respectively, p=0.01). Recurrent angina was 4.11% in the DES group and 6.36% in CABG group (p = 0.41). Conclusions : In the current study the two procedures had similar long-term results, even though the surgical approach was associated with increased in-hospital complications and longer hospitalization. Therefore, both revascularization modalities can be used to treat pLAD lesions in pts with CSA.


2019 ◽  
Vol 12 (2) ◽  
pp. 110 ◽  
Author(s):  
A. V. Frolov ◽  
A. B. Nishonov ◽  
N. I. Zagorodnikov ◽  
S. V. Ivanov ◽  
L. S. Barbarash

2020 ◽  
pp. 021849232097595
Author(s):  
Andrew CW Baldwin ◽  
George Tolis

Recent trends in cardiac surgery have encouraged total arterial coronary revascularization, citing advantages in long-term patency and overall mortality. Often relying on sequenced, composite, and free-graft strategies, total arterial coronary revascularization is limited by conduit availability and surgical complexity. We present the use of bilateral internal mammary artery grafts to achieve nonsequential 3-vessel total arterial coronary revascularization using the preserved distal bifurcation of the right internal mammary artery. Utilization of distal internal mammary artery branches should be considered a viable strategy in select patients and can broaden the opportunities for total arterial coronary revascularization in patients with multivessel coronary disease.


Swiss Surgery ◽  
2001 ◽  
Vol 7 (5) ◽  
pp. 209-210 ◽  
Author(s):  
Piergiorgio Tozzi ◽  
Jan Otto Solem ◽  
Boumzebra ◽  
Antonio Mucciolo ◽  
Xavier Mueller ◽  
...  

Background: A device to perform sutureless end-to-side coronary artery anastomosis has been developed by means of stent technology (GraftConnector). The present study assesses the long-term quality of the GraftConnector anastomosis in a sheep model. Methods: In 8 adult sheep, 40-55kg in weight, through left anterior thoracotomy, the right internal mammary artery (RIMA) was prepared and connected to the left anterior descending artery (LAD) by means of GraftConnector, on beating heart, without using any stabiliser. Ticlopidine 250mg/day for anticoagulation for 4 weeks and Aspirin 100mg/day for 6 months were given. The animals were sacrificed after 6 months and histological examination of anastomoses was carried out after slicing with the connector in situ for morphological analysis. Results: All animals survived at 6 months. All anastomoses were patent and mean luminal width at histology was 1.8 0.2mm; mean myointima hyperplasia thickness was 0.21 0.1mm. Conclusions: Long-term results demonstrate that OPCABGs performed with GraftConnector had 100% patency rate. The mean anastomotic luminal width corresponds to mean LAD's adult sheep diameter. We may speculate that myointima hyperplasia occurred as a result of local device oversizing.


Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Emmeline Ruka ◽  
François Dagenais ◽  
Siamak Mohammadi ◽  
Vincent Chauvette ◽  
Pierre Voisine

Context: The prevalence of obesity has increased over the last decade. Although bilateral internal mammary artery (BIMA) grafting for coronary revascularization is associated with better survival in the general population, it is also a risk factor for deep sternal wound infection (DSWI), a complication more frequently seen in the obese population. The aim of this study is to determine the short and long-term outcomes of the use of BIMA in obese patients undergoing cardiac surgery, assessing the impact on survival and the incidence of DSWI. Methodology: This is a single center retrospective cohort study with prospectively collected data. We included obese patients (BMI ≥ 30 kg/m2) undergoing coronary artery bypass grafting (CABG) between April 1991 and April 2014 in our institution. Propensity score matching was conducted for the entire population studied. Results: Results showed that 5608 obese patients underwent CABG during the study period. After propensity scoring, 494 patients receiving BIMA revascularization were matched to 5089 patients receiving single internal mammary artery (SIMA) revascularization. All pre-operative characteristics were comparable except for a higher prevalence of heart failure in the SIMA group. In-hospital post-operative mortality in the two groups was comparable (1.0% BIMA vs 1.8% SIMA, p=0.86). In-hospital DSWI was also comparable (1.2% BIMA vs 1.0% SIMA, p=0.63). However total DSWI (including post-discharge DSWI, median time 19 days) was significantly higher in the BIMA group compared to the SIMA group (3.6% vs 2.2%; p<0.0001). Over a median follow-up of 7.2 years (mean follow-up 7.7 ± 4.2 years), there was no observed long-term survival advantage in the BIMA vs the SIMA group (p=0.22). Conclusion: Using BIMA instead of SIMA increases the risk of DSWI in obese patients. The use of BIMA is not associated with better survival compared to the use of SIMA in this population. These results suggest that the increased short-term risk of post-operative infection associated with BIMA revascularization is not offset by a long-term survival benefit. Given the increased risk of DSWI and absence of mid- to long-term survival benefit, caution should be exerted when selecting the use of BIMA grafting in the obese population.


2021 ◽  
Vol 2021 (2) ◽  
Author(s):  
Walid Simry ◽  
Ahmed Afifi

In coronary artery bypass grafting (CABG), the use of an internal mammary artery (IMA) to graft the left anterior descending coronary artery (LAD) improves survival and reduces the need for repeat revascularization. The other IMA, radial artery (RA), and saphenous vein (SV) have contested to complete the surgical revascularization. For that purpose, SV remains the most commonly used conduit despite current evidence in favor of arterial grafts. To determine which conduit is best for grafting the second most important coronary artery, Buxton and colleagues have recently published the long term results of their “Radial Artery Patency and Clinical Outcomes (RAPCO)” trial.


Circulation ◽  
2017 ◽  
Vol 136 (18) ◽  
pp. 1676-1685 ◽  
Author(s):  
Alexander Iribarne ◽  
Joseph D. Schmoker ◽  
David J. Malenka ◽  
Bruce J. Leavitt ◽  
Jock N. McCullough ◽  
...  

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