Hormone-sensitive lipase of rat adipose tissue correlation of activity with a protein of molecular weight 84 000

1980 ◽  
Vol 619 (2) ◽  
pp. 440-444 ◽  
Author(s):  
John C. Khoo ◽  
Lars Berglund ◽  
Dennis Jensen ◽  
Daniel Steinberg
Keyword(s):  
Molecular Weight ◽  
Adipose Tissue ◽  
Hormone Sensitive Lipase ◽  
Hormone Sensitive ◽  
Rat Adipose Tissue

scholarly journals Hormone-sensitive lipase of rat adipose tissue. Purification and some properties.

1981 ◽  
Vol 256 (12) ◽  
pp. 6311-6320
Author(s):  
G. Fredrikson ◽  
P. Strålfors ◽  
N.O. Nilsson ◽  
P. Belfrage
Keyword(s):  
Adipose Tissue ◽  
Hormone Sensitive Lipase ◽  
Hormone Sensitive ◽  
Rat Adipose Tissue

Exercise and the cAMP system in rat adipose tissue. I. Lipid mobilization

1981 ◽  
Vol 50 (2) ◽  
pp. 250-254 ◽  
Author(s):  
L. B. Oscai ◽  
R. A. Caruso ◽  
A. C. Wergeles ◽  
W. K. Palmer
Keyword(s):  
Adipose Tissue ◽  
Binding Capacity ◽  
Exercise Program ◽  
Treadmill Running ◽  
Hormone Sensitive Lipase ◽  
Male Rats ◽  
Tissue Slices ◽  
Hormone Sensitive ◽  
Camp System ◽  
Rat Adipose Tissue

Protein kinase (PK) and hormone-sensitive lipase (HSL) were measured at rest in adipose tissue of untrained male rats and in that of animals subjected to a strenuous program of treadmill running. Total amounts of PK activity (decreased from 860 +/- 104 to 474 +/- 53 pmol.min-1. (10(6) cells)-1 (P less than 0.01) as a result of exercise training. At the same time, binding capacity for adenosine 3',5'-cyclic monophosphate (cAMP) was elevated in the runners. These data suggest a functional loss in catalytic activity without a loss in binding capacity. In addition, the results provide evidence that the capacity of PK to activate HSL is reduced in adipocytes of physically trained rats. HSL activity was measured in both adipose tissue slices and isolated adipocytes. The results show that the levels of activity of HSL did not increase as a result of the running program. These results provide evidence that the lipolytic capacity of adipocytes of normal untrained male rats is sufficiently large to meet the increased demand for free fatty acids imposed by the exercise program without the need for an adaptive increase in HSL activity.

Use of protein G for preparation and characterization of rabbit antibodies against rat adipose tissue hormone-sensitive lipase

1987 ◽  
Vol 97 (1) ◽  
pp. 65-70 ◽  
Author(s):  
Gudrum Fredrikson ◽  
Staffan Nilsson ◽  
Håkan Olsson ◽  
Lars Björck ◽  
Bo Åkerström ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Hormone Sensitive Lipase ◽  
Protein G ◽  
Hormone Sensitive ◽  
Rat Adipose Tissue
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