Interaction of cyclophosphamide metabolites with membrane proteins: An in vitro study with rabbit liver microsomes and human red blood cells

1982 ◽  
Vol 31 (22) ◽  
pp. 3535-3541 ◽  
Author(s):  
Dieter B. Wildenauer ◽  
Christiana E. Oehlmann
Keyword(s):  
Membrane Proteins ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Liver Microsomes ◽  
In Vitro Study ◽  
Vitro Study ◽  
Rabbit Liver ◽  
Human Red Blood Cells

Eryptosis-inducing activity of bisphenol A and its analogs in human red blood cells (in vitro study)

2016 ◽  
Vol 307 ◽  
pp. 328-335 ◽  
Author(s):  
Aneta Maćczak ◽  
Monika Cyrkler ◽  
Bożena Bukowska ◽  
Jaromir Michałowicz
Keyword(s):  
Bisphenol A ◽  
Red Blood Cells ◽  
Blood Cells ◽  
In Vitro Study ◽  
Vitro Study ◽  
Human Red Blood Cells

The Relationship Between Extra- and Intracellular Lithium Concentration in Human Red Blood Cells: an in Vitro Study

1977 ◽  
Vol 131 (1) ◽  
pp. 59-62 ◽  
Author(s):  
John J. Ratey ◽  
Alan G. Mallinger
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Lithium Concentration ◽  
In Vitro Study ◽  
Individual Variability ◽  
Vitro Study ◽  
Normal Volunteers ◽  
Human Red Blood Cells ◽  
The Relationship

SummaryRed blood cells (RBCs) from normal volunteers were incubated in vitro at four different extracellular lithium concentrations. Extracellular lithium concentration affected RBC lithium accumulation in several ways. As extracellular lithium concentration increased, the inter-individual variability of RBC lithium accumulation increased. Furthermore, the ratio of RBC lithium concentration to extracellular lithium concentration (lithium ratio) increased in relation to increasing extracellular lithium concentration. A lack of agreement among the authors of recent reports dealing with the significance of the lithium ratio as a psychobiological measure has been noted. It is suggested that this lack of agreement may be due, in part, to the study of patients with differing levels of extracellular lithium.

Phenol and chlorinated phenols exhibit different apoptotic potential in human red blood cells ( in vitro study)

2018 ◽  
Vol 61 ◽  
pp. 95-101 ◽  
Author(s):  
Jaromir Michałowicz ◽  
Anna Włuka ◽  
Monika Cyrkler ◽  
Aneta Maćczak ◽  
Paulina Sicińska ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
In Vitro Study ◽  
Vitro Study ◽  
Chlorinated Phenols ◽  
Human Red Blood Cells

scholarly journals An In Vitro Study of the Effect of Cytotoxic Triorganotin Dimethylaminophenylazobenzoate Complexes on Red Blood Cells

2018 ◽  
Vol 251 (5-6) ◽  
pp. 735-745 ◽  
Author(s):  
Hanna Pruchnik ◽  
Aleksandra Włoch ◽  
Dorota Bonarska-Kujawa ◽  
Halina Kleszczyńska
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
In Vitro Study ◽  
Vitro Study

In vitro study on the partitioning of red blood cells using a microchannel network

2022 ◽  
Vol 140 ◽  
pp. 104281
Author(s):  
Toru Hyakutake ◽  
Hiroki Abe ◽  
Yohei Miyoshi ◽  
Manabu Yasui ◽  
Rina Suzuki ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
In Vitro Study ◽  
Vitro Study

scholarly journals Evaluation of chromium in red blood cells as an indicator of exposure to hexavalent chromium: An in vitro study

2016 ◽  
Vol 255 ◽  
pp. 63-70 ◽  
Author(s):  
Jérôme Devoy ◽  
Antoine Géhin ◽  
Samuel Müller ◽  
Mathieu Melczer ◽  
Aurélie Remy ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Hexavalent Chromium ◽  
Blood Cells ◽  
In Vitro Study ◽  
Vitro Study

In vitro study of the specific interaction between poly(2-dimethylamino ethylmethacrylate) based polymers with platelets and red blood cells

2015 ◽  
Vol 492 (1-2) ◽  
pp. 55-64 ◽  
Author(s):  
Luca Flebus ◽  
François Lombart ◽  
Lucía Martinez-Jothar ◽  
Chantal Sevrin ◽  
Céline Delierneux ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Specific Interaction ◽  
In Vitro Study ◽  
Vitro Study

Influence of plasma preparations and donor red blood cells on the antioxidant capacity of blood from newborn babies: an in vitro study

1996 ◽  
Vol 85 (2) ◽  
pp. 220-224 ◽  
Author(s):  
RMW Moison ◽  
EJHA Hoof ◽  
PC Clahsen ◽  
D Zoeren-Grobben ◽  
HM Berger
Keyword(s):  
Antioxidant Capacity ◽  
Red Blood Cells ◽  
Blood Cells ◽  
In Vitro Study ◽  
Vitro Study

Melatonin Ameliorates BPA Induced Oxidative Stress in Human Red Blood Cells: An In vitro Study

2020 ◽  
Vol 20 (8) ◽  
pp. 1321-1327
Author(s):  
Saleh M. Abdullah ◽  
Hina Rashid
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Red Blood Cells ◽  
Blood Cells ◽  
In Vitro Study ◽  
Limited Data ◽  
Human Red Blood Cells ◽  
Living Organisms ◽  
Human Rbcs

Background: Bisphenol A (BPA) is a xenobiotic that causes oxidative stress in various organs in living organisms. Blood cells are also an endpoint where BPA is known to cause oxidative stress. Blood cells, especially red blood cells (RBCs), are crucial for maintaining homeostasis and overall wellbeing of the organism. They are highly susceptible to oxidative stress induced by xenobiotics. However, there is limited data about the oxidative stress induced by BPA in blood, especially in red blood cells. This study was carried out to evaluate BPA induced oxidative stress in human RBCs in vitro and its amelioration by melatonin. Objective: To find if melatonin exerts a protective effect on the oxidative stress induced by the BPA in human red blood cells in vitro. Methods: The erythrocyte suspensions (2 ml) were divided into six groups and treated with 0, 50, 100, 150, 200, and 250 μg/ml of BPA. Another set of erythrocyte suspension with similar BPA treatment and 50 μM Melatonin per group was also set. Incubations lasted for 12 hrs in the dark. Lipid peroxidation, glutathione, glutathione reductase, catalase, and superoxide dismutase were measured as indicators of oxidative stress. Results: BPA caused a significant increase in lipid peroxidation. A decrease in GSH levels was also observed. The activities of all the studied antioxidants also decreased with BPA treatment. Melatonin was seen to mitigate the oxidative stress induced by BPA. Conclusion: Treatment of red blood cells with BPA caused an increase in oxidative stress, while melatonin decreased the induced oxidative stress.

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