Effects of anti-inflammatory, anticoagulant and vasoactive compounds on tail bleeding time, whole blood coagulation time and platelet retention by glass beads in rats

1976 ◽  
Vol 8 (2) ◽  
pp. 179-193 ◽  
Author(s):  
F. De Clerck ◽  
J. Goossens ◽  
R. Reneman
Keyword(s):  
Blood Coagulation ◽  
Whole Blood ◽  
Bleeding Time ◽  
Glass Beads ◽  
Coagulation Time ◽  
Whole Blood Coagulation Time ◽  
Anti Inflammatory

A Solid State Whole Blood Coagulation Time Device

1966 ◽  
Vol 46 (4) ◽  
pp. 463-471
Author(s):  
Joseph Beeman ◽  
Alma Miller ◽  
Sam CAmarena
Keyword(s):  
Solid State ◽  
Blood Coagulation ◽  
Whole Blood ◽  
Coagulation Time ◽  
Whole Blood Coagulation Time

Investigations of the Dose of Heparin and Whole Blood Coagulation Time during Endovascular Surgery

1997 ◽  
Vol 3 (2_suppl) ◽  
pp. 215-217 ◽  
Author(s):  
S. Nagai ◽  
A. Kurata ◽  
R. Tanaka ◽  
K. Irikura ◽  
Y. Miyasaka ◽  
...  
Keyword(s):  
Blood Coagulation ◽  
Whole Blood ◽  
Initial Level ◽  
Thrombus Formation ◽  
Constant Level ◽  
Bleeding Tendency ◽  
Coagulation Time ◽  
Continuous Administration ◽  
Heparin Administration ◽  
Whole Blood Coagulation Time

We chronologically determined whole blood coagulation time during continuous heparin administration, and investigated optimal doses of heparin in thirty-seven vascular surgery cases. ACT was determined with Hemochron 401. Heparin (2000 IU) was administered by bolus injection at the beginning of intravascular surgery, which was followed by continuous injection of 20 to 160 IU/kg/h. ACT determined before and 30 minutes after heparin administration were compared. There were no complications. ACT was maintained at a nearly constant level by continuous heparin administration. The dose of heparin required to maintain ACT at a level 1.5 to 2 times the initial level was 20 to 60 IU/kg/h. ACT was prolonged by more than three times in two of the ten subjects who were given heparin at a dose of 70 IU/kg/h or more. Continuous administration of heparin allowed maintenance of ACT at a nearly constant level during intravascular surgery. ACT was maintained within the range which is believed to be effective for prevention of thrombus formation (approximately 1.5 to 2.0 times larger than the initial level) by continuous administration of 20 to 60 IU/kg/h of heparin. ACT was, however, prolonged to more than three times the initial level in some subjects who were given 70 IU/kg/h or higher doses, suggesting the risk of a bleeding tendency. Accordingly, it is ideal to continue heparin administration at appropriate doses, while measuring ACT. The results of our study should serve as a useful standard for meeting this goal.

Measurement of Whole Blood Coagulation Time by Laser Speckle Pattern Correlation

2020 ◽  
Vol 54 (4) ◽  
pp. 262-266
Author(s):  
Yu. D. Liushnevskaya ◽  
F. A. Gubarev ◽  
L. Li ◽  
A. V. Nosarev ◽  
V. S. Gusakova
Keyword(s):  
Blood Coagulation ◽  
Whole Blood ◽  
Speckle Pattern ◽  
Laser Speckle ◽  
Coagulation Time ◽  
Pattern Correlation ◽  
Whole Blood Coagulation Time

Metals in air pollution particles decrease whole-blood coagulation time

2010 ◽  
Vol 22 (8) ◽  
pp. 621-626 ◽  
Author(s):  
Rahul G. Sangani ◽  
Joleen M. Soukup ◽  
Andrew J. Ghio
Keyword(s):  
Air Pollution ◽  
Blood Coagulation ◽  
Whole Blood ◽  
Coagulation Time ◽  
Whole Blood Coagulation Time
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