Reliability and validity of a quality of life measure for lung and colon cancer patients

1986 ◽  
Vol 7 (3) ◽  
pp. 258
Author(s):  
Lucille S. Ryan ◽  
Thomas E. Moritz ◽  
Leo R. Zacharski
Keyword(s):  
Quality Of Life ◽  
Colon Cancer ◽  
Cancer Patients ◽  
Reliability And Validity ◽  
Life Measure

Further development of a quality of life measure for cancer patients: The rotterdam symptom checklist (revised)

1992 ◽  
Vol 1 (1) ◽  
pp. 35-44 ◽  
Author(s):  
M. Watson ◽  
M. Law ◽  
G. P. Maguire ◽  
B. Robertson ◽  
S. Greer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Symptom Checklist ◽  
Life Measure ◽  
Further Development ◽  
Rotterdam Symptom Checklist

Determinants of health-related quality of life in colon cancer patients include stoma and smoking habits, but not type of surgery

2019 ◽  
Author(s):  
Catarina Tiselius ◽  
Andreas Rosenblad ◽  
Eva Strand ◽  
Kennet Smedh
Keyword(s):  
Quality Of Life ◽  
Colon Cancer ◽  
Regression Analysis ◽  
Cancer Patients ◽  
Linear Regression Analysis ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Abstract Background: Health-related quality of life (HRQoL) has gained increased attention in cancer care. Studies have shown that poor QoL might worsen the cancer related prognosis. The aim of this study was to investigate HRQoL in patients with colon cancer and to compare data with reference values from the general population in Sweden at diagnosis (baseline) and at six months of follow-up. Methods : This was a prospective population-based study of colon cancer patients from Västmanland County, Sweden, included between March 2012 and September 2016. HRQoL was measured using the cancer-specific EORTC QLQ-C30 questionnaire. Data on HRQoL was compared with Swedish population reference values. Multiple linear regression analysis adjusted for age, sex, body mass index (BMI), American Society of Anaesthesiology (ASA) physical status classification, emergency/elective surgery, and resection with/without a stoma and tumour stage (TNM), was used. Results : A total of 67% (376/561) of all incident colon cancer patients (196 [52.1%] females) were included. Mean (range) age was 73 (30-96) years. The univariate analysis showed that patients with colon cancer had worse QoL (8/15 parameters) compared with a Swedish reference population both at baseline and at 6 months follow-up. Furthermore, linear regression analysis showed that patients with more comorbidity (ASA 3 and 4), smokers and patients planned to be operated on with a stoma, were at higher risks for poor QoL than the other included patients. Conclusions : The reported determinants of HRQoL may be used to identify risk groups and enable individualized care for patients that need more support from health care.

Test/retest study of the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire.

1995 ◽  
Vol 13 (5) ◽  
pp. 1249-1254 ◽  
Author(s):  
M J Hjermstad ◽  
S D Fossa ◽  
K Bjordal ◽  
S Kaasa
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Reliability And Validity ◽  
Life Questionnaire ◽  
European Organization ◽  
Retest Reliability ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Test Retest Reliability

PURPOSE The European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) is a well-validated instrument that assesses health-related quality of life (HRQOL) in cancer patients. It is used in cancer clinical trials in Europe, Canada, and the United States, and has demonstrated high reliability and validity in different groups of cancer patients. Despite thorough testing of reliability and validity, we have not identified any reports on its test/retest reliability; thus, a test/retest study was performed at the Norwegian Radium Hospital (NRH). MATERIALS AND METHODS Cancer patients from the outpatient clinic who were off treatment for > or = 3 months were eligible for the study. The EORTC QLQ-C30 was given to the patients when they presented for their visit. The second questionnaire was received by the patients 4 days later. Of 291 eligible patients, 270 (93%) agreed to participate and 190 (73%) completed both questionnaires. RESULTS The test/retest reliability measured by Pearson's correlation coefficient was high for all functional scales, with a range from .82 for cognitive and role function to .91 for physical function. The r value for global HRQOL was .85. For the symptom scales--nausea/vomiting, fatigue, and pain--the coefficients were .63, .83, and .86, respectively. The single-item coefficients ranged from .72 for diarrhea to .84 for financial impact. The Spearman rank correlation was in the same range for all dimensions. CONCLUSION The EORTC QLQ-C30 seems to yield high test/retest reliability in patients with various cancer diagnoses whose condition is not expected to change during the time of measurement.

scholarly journals Biopsychosocial and clinical characteristics in patients with resected breast and colon cancer at the beginning and end of adjuvant treatment

BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Teresa García-García ◽  
Alberto Carmona-Bayonas ◽  
Paula Jimenez-Fonseca ◽  
Carlos Jara ◽  
Carmen Beato ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Decision Making ◽  
Colon Cancer ◽  
Cancer Patients ◽  
Adjuvant Treatment ◽  
Perceived Social Support ◽  
Shared Decision ◽  
Breast Cancer Patients

Abstract Background The aim of this study was to analyze biopsychosocial factors affecting how patients cope with cancer and adjuvant treatment and to appraise psychological distress, coping, perceived social support, quality of life and SDM before and after adjuvant treatment in breast cancer patients compared to colon cancer patients. Methods NEOcoping is a national, multicenter, cross-sectional, prospective study. The sample comprised 266 patients with colon cancer and 231 with breast cancer. The instruments used were the Brief Symptom Inventory (BSI), Mini-Mental Adjustment to Cancer (Mini-MAC), Multidimensional Scale of Perceived Social Support (MSPSS), Shared Decision-Making Questionnaire-Patient (SDM-Q-9) and Physician’s (SDM-Q-Doc), and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ). Results Breast cancer patients reacted worse to the diagnosis of cancer with more symptoms of anxiety, depression, and somatization, and were less satisfied with their involvement than those with colon cancer (p = 0.003). Participants with colon cancer were older and had more physical symptoms and functional limitations at the beginning of adjuvant treatment, while there were scarcely any differences between the two groups at the end of adjuvancy, at which time both groups suffered greater psychological and physical effects and scored lower on coping strategies, except for anxious preoccupation. Conclusions Breast cancer patients need more information and involvement of the oncologist in shared decision-making, as well as and more medical and psychological support when beginning adjuvant treatment. Both breast and colon cancer patients may require additional psychological care at the end of adjuvancy.

Fatigue control in metastatic colon cancer treated with capecitabine and oxaliplatin.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e19628-e19628
Author(s):  
Fernanda Maris Peria ◽  
Lilian Andrade Sá ◽  
Harley Francisco Oliveira ◽  
Josiane Cheli Vettori ◽  
Daniela Pretti da Cunha Tirapelli ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colon Cancer ◽  
Cancer Patients ◽  
Palliative Chemotherapy ◽  
Large Population ◽  
Concurrent Chemotherapy ◽  
Metastatic Colon Cancer ◽  
Chemotherapy Treatment ◽  
Chi Squared

e19628 Background: Fatigue is one of the most frequent symptoms in cancer patients, characterized by profound fatigue that is not relieved by rest. This symptom can be identified at the time of diagnosis and could affects up to 90% of patients undergoing cancer treatment. There are some instruments available in the literature that can characterize the presence of fatigue through clinical questioning. Methods: Considering the large population of patients with metastatic colorectal cancer treated with chemotherapy and the prevalence of fatigue in these patients, this study evaluated the presence of fatigue in 27 metastatic colon cancer patients before the first, second, third and fourth cycles of fist line palliative chemotherapy regimen containing CAPOX (capecitabine and oxaliplatin) by applying the evaluation questionnaire FACIT-F fatigue. Results: The results post Friedman chi-squared test demonstrated that there was no improvement of fatigue during these four cycles of CAPOX palliative chemotherapy (p=0,2574). The FACIT-G analysis demonstrated no worsening of quality of life (p=0,2411) during and between the four cycles of chemo. All different parameters included in FACIT-F questionnaires: emotional (p=0,2629), physical (p=0,3199), familiar (p=0,1456), functional (p=0,8662) and specific fatigue topic (p=0,7569) confirmed no difference between the cycles. Conclusions: Despite the metastatic stage of colon cancer patients and concurrent chemotherapy treatment, there was no fatigue improvement during the four first CAPOX chemo cycles courses and there was the maintenance of quality of life.

scholarly journals Reliability and validity of the EORTC QLQ-C30 in palliative care cancer patients

Open Medicine ◽  
2009 ◽  
Vol 4 (3) ◽  
pp. 348-357 ◽  
Author(s):  
Hubert Jocham ◽  
Theo Dassen ◽  
Guy Widdershoven ◽  
Ruud Halfens
Keyword(s):  
Quality Of Life ◽  
Palliative Care ◽  
Cancer Patients ◽  
Symptom Control ◽  
Reliability And Validity ◽  
European Organization ◽  
Wide Range ◽  
Eortc Qlq C30 ◽  
Eortc Qlq

AbstractPalliative care aims at improving the patient’s quality of life. The assessment of this quality of life (QoL) is crucial for the evaluation of palliative care outcome. Many patients require hospital admissions for symptom control during their cancer journey and most of them die in hospitals, although they would like to stay at home until the end of their lives. In 1986, the European Organization for Research and Treatment (EORTC) initiated a research programme to develop an integrated, modular approach for evaluating the quality of life of patients participating in international clinical trials. This questionnaire measures cancer patients’ physical, psychological and social functions and was used in a wide range of clinical cancer trials with large numbers of research groups and also in various other non-trial studies. The aim of this study was to evaluate the psychometric properties, especially the reliability, validity and applicability of the EORTC QLQ-C30 in a German sample of terminally ill cancer patients receiving palliative care in different settings. The questionnaire was well accepted in the present patient population. Scale reliability was good (pre-treatment 0.80) especially for the functional scale. The results support the reliability and validity of the QLQ-C30 (version 3.0) as a measure of the health-related quality of life in German cancer patients receiving palliative care treatment.

Reliability and validity of an HIV-specific health-related quality-of-life measure for use with injecting drug users

AIDS ◽  
1996 ◽  
Vol 10 (14) ◽  
pp. 1699-1705 ◽  
Author(s):  
Maria D. Carretero ◽  
Adrian P. Burgess ◽  
Pilar Soler ◽  
Miguel Soler ◽  
José Catalán
Keyword(s):  
Quality Of Life ◽  
Drug Users ◽  
Reliability And Validity ◽  
Injecting Drug Users ◽  
Health Related Quality ◽  
Life Measure ◽  
Related Quality ◽  
Health Related ◽  
Specific Health

scholarly journals Development of expert system that improve the decision-making process with an emphasis on health-related quality of life in elderly patients with a colon cancer.

2019 ◽  
Vol 5 (suppl) ◽  
pp. 113-113
Author(s):  
Polina Shilo ◽  
Aleksandra Kanina
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Colon Cancer ◽  
Prediction Model ◽  
Cancer Patients ◽  
Health Related Quality ◽  
Model Quality ◽  
Related Quality ◽  
Health Related

113 Background: Health-Related Quality of Life (HRQoL) is an important issue for elderly patients with colon cancer. We created the expert system which allows to predict low level of HRQoL and accessed it’s quality by using several simulation studies. Methods: We performed a systematic review to figure out the known factors associated with low level of HRQoL in elderly colon cancer patients. The searches were performed in PubMed. We accessed the possible impact of several factors affecting HRQoL, including symptoms, comorbidities and treatment toxicity. All relevant factors were included in prediction model. We assigned the different weights to different factors based on evaluation of clinical studies to develop the logistic regression and Markov stochastic model later. As we needed a binary dependent variable we performed the ROC analysis to figure out an optimal cutoff of HRQoL. Then we simulated a partly virtual dataset based on elderly colon cancer patients diagnosed in Davidovskiy Hospital to evaluate the prediction model quality. All statistical calculations were performed in RStudio. The simulation part was performed using simFrame R package. Results: Twenty two studies with a total number of 2516 patients were included in our systematic review. The 39 factors with different weights were included prediction model with different weights assigned. The weights range varied from 1 to 18.6. The adjusted proportion of summary score's variance (R2 ) varied from 0.09 to 0.47 in univariate analysis. The final logistic regression model quality was moderate: the Nagelkerke R-square coefficient was 57.9. However, the developed model showed a 76% sensitivity and 61% specificity in predicting of lower HRQoL level. Conclusions: Our prediction model allows to prospectively manage of elderly colon cancer patients, making the emphasis on HRQoL. However, the present study has some restrictions: simulation nature of internal validation, possible underestimating of the rare events impact. The long-term comprehensive approach with external validation using large real data analysis is needed to evaluate our prediction model.

scholarly journals Reliability and Validity of the Hospice Quality of Life Scale for Korean Cancer Patients

2009 ◽  
Vol 37 (2) ◽  
pp. 156-167 ◽  
Author(s):  
Su Hyun Kim ◽  
Youn Seon Choi ◽  
Juneyoung Lee ◽  
Sang Cheul Oh ◽  
Chang Hwan Yeom ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Reliability And Validity ◽  
Quality Of Life Scale ◽  
Life Scale
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