Overexpression of Bcl-2 in a murine dopaminergic neuronal cell line leads to neurite outgrowth

1996 ◽  
Vol 202 (3) ◽  
pp. 161-164 ◽  
Author(s):  
Young J. Oh ◽  
Barbara C. Swarzenski ◽  
Karen L. O'Malley
Keyword(s):  
Neurite Outgrowth ◽  
Cell Line ◽  
Neuronal Cell ◽  
Neuronal Cell Line ◽  
Dopaminergic Neuronal Cell

Activation of Autophagy Contributes to the Angiotensin II-Triggered Apoptosis in a Dopaminergic Neuronal Cell Line

2015 ◽  
Vol 53 (5) ◽  
pp. 2911-2919 ◽  
Author(s):  
Qing Gao ◽  
Teng Jiang ◽  
Hong-Rui Zhao ◽  
Liang Wu ◽  
You-Yong Tian ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Cell Line ◽  
Neuronal Cell ◽  
Neuronal Cell Line ◽  
Dopaminergic Neuronal Cell

TorsinA negatively controls neurite outgrowth of SH-SY5Y human neuronal cell line

2004 ◽  
Vol 1012 (1-2) ◽  
pp. 75-81 ◽  
Author(s):  
Giulia Ferrari-Toninelli ◽  
Sarah Paccioretti ◽  
Simona Francisconi ◽  
Daniela Uberti ◽  
Maurizio Memo
Keyword(s):  
Neurite Outgrowth ◽  
Cell Line ◽  
Neuronal Cell ◽  
Neuronal Cell Line ◽  
Human Neuronal Cell

scholarly journals Rab35 and its effectors promote formation of tunneling nanotubes in neuronal cells

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Shaarvari Bhat ◽  
Nina Ljubojevic ◽  
Seng Zhu ◽  
Mitsunori Fukuda ◽  
Arnaud Echard ◽  
...  
Keyword(s):  
Actin Cytoskeleton ◽  
Neurite Outgrowth ◽  
Cell Line ◽  
Vesicle Trafficking ◽  
Neuronal Cell ◽  
Rab Gtpases ◽  
Tunneling Nanotubes ◽  
Neuronal Cell Line ◽  
Unique Identity ◽  
Cellular Components

Abstract Tunneling nanotubes (TNTs) are F-actin rich structures that connect distant cells, allowing the transport of many cellular components, including vesicles, organelles and molecules. Rab GTPases are the major regulators of vesicle trafficking and also participate in actin cytoskeleton remodelling, therefore, we examined their role in TNTs. Rab35 functions with several proteins that are involved in vesicle trafficking such as ACAP2, MICAL-L1, ARF6 and EHD1, which are known to be involved in neurite outgrowth. Here we show that Rab35 promotes TNT formation and TNT-mediated vesicle transfer in a neuronal cell line. Furthermore, our data indicates that Rab35-GTP, ACAP2, ARF6-GDP and EHD1 act in a cascade mechanism to promote TNT formation. Interestingly, MICAL-L1 overexpression, shown to be necessary for the action of Rab35 on neurite outgrowth, showed no effect on TNTs, indicating that TNT formation and neurite outgrowth may be processed through similar but not identical pathways, further supporting the unique identity of these cellular protrusions.

A neuronal cell line (PC12) expresses two β1-class integrins—α1β1, and α3β1—that recognize different neurite outgrowth-promoting domains in laminin

Neuron ◽  
1990 ◽  
Vol 5 (5) ◽  
pp. 651-662 ◽  
Author(s):  
K.J. Tomaselli ◽  
D.E. Hall ◽  
L.A. Flier ◽  
K.R. Gehlsen ◽  
D.C. Turner ◽  
...  
Keyword(s):  
Neurite Outgrowth ◽  
Cell Line ◽  
Neuronal Cell ◽  
Neuronal Cell Line

Overexpression of Bcl-2 attenuates MPP+, but not 6-ODHA, induced cell death in a dopaminergic neuronal cell line

1995 ◽  
Vol 2 (3) ◽  
pp. 157-167 ◽  
Author(s):  
Young J. Oh ◽  
Shou C. Wong ◽  
Mark Moffat ◽  
Karen L. O'Malley
Keyword(s):  
Cell Death ◽  
Cell Line ◽  
Neuronal Cell ◽  
Neuronal Cell Line ◽  
Dopaminergic Neuronal Cell
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