A highly conserved region in the hormone-binding domain of the human estrogen receptor functions as an efficient transactivation domain in yeast

Benoit Pierrat; David M. Heery; Pierre Chambon; Régine Losson

doi:10.1016/0378-1119(94)90096-5

A highly conserved region in the hormone-binding domain of the human estrogen receptor functions as an efficient transactivation domain in yeast

Gene ◽

10.1016/0378-1119(94)90096-5 ◽

1994 ◽

Vol 143 (2) ◽

pp. 193-200 ◽

Cited By ~ 49

Author(s):

Benoit Pierrat ◽

David M. Heery ◽

Pierre Chambon ◽

Régine Losson

Keyword(s):

Estrogen Receptor ◽

Binding Domain ◽

Transactivation Domain ◽

Hormone Binding ◽

Human Estrogen Receptor ◽

Conserved Region ◽

Hormone Binding Domain

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Mutagenesis of cysteines in the hormone binding domain of the human estrogen receptor. Alterations in binding and transcriptional activation by covalently and reversibly attaching ligands

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)99101-5 ◽

1991 ◽

Vol 266 (17) ◽

pp. 10880-10887 ◽

Cited By ~ 2

Author(s):

J.C. Reese ◽

B.S. Katzenellenbogen

Keyword(s):

Estrogen Receptor ◽

Transcriptional Activation ◽

Binding Domain ◽

Hormone Binding ◽

Human Estrogen Receptor ◽

Hormone Binding Domain

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Identification of charged residues in an N-terminal portion of the hormone-binding domain of the human estrogen receptor important in transcriptional activity of the receptor.

Molecular Endocrinology ◽

10.1210/mend.7.11.8114756 ◽

1993 ◽

Vol 7 (11) ◽

pp. 1408-1417 ◽

Cited By ~ 1

Author(s):

F Pakdel ◽

J C Reese ◽

B S Katzenellenbogen

Keyword(s):

Estrogen Receptor ◽

Transcriptional Activity ◽

Binding Domain ◽

Hormone Binding ◽

Terminal Portion ◽

Charged Residues ◽

Human Estrogen Receptor ◽

Hormone Binding Domain

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Identification of Amino Acids in the Hormone Binding Domain of the Human Estrogen Receptor Important in Estrogen Binding

Journal of Biological Chemistry ◽

10.1074/jbc.271.33.20053 ◽

1996 ◽

Vol 271 (33) ◽

pp. 20053-20059 ◽

Cited By ~ 71

Author(s):

Kirk Ekena ◽

Karen E. Weis ◽

John A. Katzenellenbogen ◽

Benita S. Katzenellenbogen

Keyword(s):

Amino Acids ◽

Estrogen Receptor ◽

Binding Domain ◽

Hormone Binding ◽

Human Estrogen Receptor ◽

Estrogen Binding ◽

Hormone Binding Domain

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Identification of charged residues in an N-terminal portion of the hormone-binding domain of the human estrogen receptor important in transcriptional activity of the receptor

Molecular Endocrinology ◽

10.1210/me.7.11.1408 ◽

1993 ◽

Vol 7 (11) ◽

pp. 1408-1417 ◽

Cited By ~ 19

Author(s):

F. Pakdel

Keyword(s):

Estrogen Receptor ◽

Transcriptional Activity ◽

Binding Domain ◽

Hormone Binding ◽

Terminal Portion ◽

Charged Residues ◽

Human Estrogen Receptor ◽

Hormone Binding Domain

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Mutational analysis of cysteine residues within the hormone-binding domain of the human estrogen receptor identifies mutants that are defective in both DNA-binding and subcellular distribution

Molecular Endocrinology ◽

10.1210/me.8.9.1215 ◽

1994 ◽

Vol 8 (9) ◽

pp. 1215-1223 ◽

Cited By ~ 10

Author(s):

S. Neff

Keyword(s):

Estrogen Receptor ◽

Dna Binding ◽

Subcellular Distribution ◽

Mutational Analysis ◽

Binding Domain ◽

Cysteine Residues ◽

Hormone Binding ◽

Human Estrogen Receptor ◽

Hormone Binding Domain

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Characterization of a temperature-sensitive mutation in the hormone binding domain of the human estrogen receptor. Studies in cell extracts and intact cells and their implications for hormone-dependent transcriptional activation.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)50174-0 ◽

1992 ◽

Vol 267 (14) ◽

pp. 9868-9873

Author(s):

J.C. Reese ◽

B.S. Katzenellenbogen

Keyword(s):

Estrogen Receptor ◽

Transcriptional Activation ◽

Binding Domain ◽

Temperature Sensitive ◽

Hormone Binding ◽

Intact Cells ◽

Cell Extracts ◽

Human Estrogen Receptor ◽

Hormone Binding Domain

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The human estrogen receptor hormone binding domain dimerizes independently of ligand activation

The Journal of Steroid Biochemistry and Molecular Biology ◽

10.1016/0960-0760(94)90192-9 ◽

1994 ◽

Vol 48 (5-6) ◽

pp. 447-452 ◽

Cited By ~ 24

Author(s):

Marie Salomonsson ◽

Johan Häggblad ◽

Bert W. O'Malley ◽

Gisela M. Sitbon

Keyword(s):

Estrogen Receptor ◽

Binding Domain ◽

Hormone Binding ◽

Ligand Activation ◽

Human Estrogen Receptor ◽

Hormone Binding Domain

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Structure-function analysis of the hormone binding domain of the human estrogen receptor by region-specific mutagenesis and phenotypic screening in yeast.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)80497-9 ◽

1993 ◽

Vol 268 (32) ◽

pp. 24089-24098

Author(s):

C.K. Wrenn ◽

B.S. Katzenellenbogen

Keyword(s):

Estrogen Receptor ◽

Structure Function ◽

Function Analysis ◽

Binding Domain ◽

Phenotypic Screening ◽

Hormone Binding ◽

Human Estrogen Receptor ◽

Hormone Binding Domain

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Substrate Induced Conformational Studies of the Hormone Binding Domain of the Human Estrogen Receptor by Fluorine NMR

10.21236/ada378790 ◽

2000 ◽

Author(s):

Linda A. Luck

Keyword(s):

Estrogen Receptor ◽

Binding Domain ◽

Hormone Binding ◽

Conformational Studies ◽

Fluorine Nmr ◽

Human Estrogen Receptor ◽

Hormone Binding Domain

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Heterologous Expression of Soluble, Active Proteins in Escherichia coli: The Human Estrogen Receptor Hormone-Binding Domain as Paradigm

Protein Expression and Purification ◽

10.1006/prep.2001.1403 ◽

2001 ◽

Vol 21 (3) ◽

pp. 500-509 ◽

Cited By ~ 12

Author(s):

Frank B. Nygaard ◽

Kenneth W. Harlow

Keyword(s):

Escherichia Coli ◽

Estrogen Receptor ◽

Heterologous Expression ◽

Binding Domain ◽

Hormone Binding ◽

Human Estrogen Receptor ◽

Hormone Binding Domain

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