“Concentric and eccentric” target signs in cerebral toxoplasmosis

Author(s):  
Dr. Ramakrishna Narra ◽  
Dr. Rajendra kumar Pamidi ◽  
Dr. Shaheen Syed
2010 ◽  
Vol 31 (6) ◽  
pp. 1469-1472 ◽  
Author(s):  
G.G. Sharath Kumar ◽  
A. Mahadevan ◽  
A.S. Guruprasad ◽  
Jerry M.E. Kovoor ◽  
P. Satishchandra ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Adam D. Roche ◽  
Dominic Rowley ◽  
Francesca M. Brett ◽  
Seamus Looby

Cerebral toxoplasmosis is one of the most common causes of focal brain lesions in immunocompromised patients, such as those with human immunodeficiency virus (HIV). Differentiating toxoplasmosis from other central nervous system (CNS) lesions provides a significant clinical challenge. Magnetic resonance (MR) imaging of the brain is key to prompt diagnosis and treatment of cerebral toxoplasmosis. Several specific signs on MRI of brain have been described in recent literature including the “concentric target sign” and “eccentric target sign.” We report a case of successfully treated HIV-associated cerebral toxoplasmosis in which both MRI signs were present simultaneously.


2020 ◽  
pp. 102490792097607
Author(s):  
Hung-Lin Hsu ◽  
Wei-Jing Lee

A 37-year-old HIV-positive woman presented to the emergency department with fever, headache, confusion, and seizures for 3 days. Computed tomography of the head with contrast demonstrated multiple ring-enhancing masses. An eccentric mural nodule in ring-enhanced mass characterizes eccentric target sign, which is pathognomonic for cerebral toxoplasmosis. The patient received anti-toxoplasmic therapy and had marked clinical improvement.


QJM ◽  
2016 ◽  
Vol 109 (8) ◽  
pp. 555-555 ◽  
Author(s):  
S. Bansal ◽  
M. Goyal ◽  
M. Modi ◽  
C. Ahuja ◽  
V. Lal

2017 ◽  
Vol 130 (7) ◽  
pp. 802-804 ◽  
Author(s):  
Melanie R.F. Greenway ◽  
Keith A. Sacco ◽  
M. Caroline Burton

2021 ◽  
pp. 194187442110053
Author(s):  
Chen Fei Ng ◽  
Chia Yin Chong

A 37-year-old man with underlying systemic lupus erythematosus and lupus nephritis presented with an episode of generalized tonic seizure. He complained of poor concentration and forgetfulness for 1 week. He suffered a relapse of lupus nephritis 4 months ago and received a course of intravenous methylprednisolone followed by oral prednisolone and mycophenolate mofetil. Clinically, there was no focal neurological deficit. Retroviral screening was negative. Magnetic resonance imaging (MRI) of the brain revealed eccentric and concentric signs which confirmed the diagnosis of cerebral toxoplasmosis.


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