Elastomeric self-healing antibacterial bioactive nanocomposites scaffolds for treating skull defect

2022 ◽  
Vol 26 ◽  
pp. 101254
Author(s):  
Yannan Li ◽  
Juan Ge ◽  
Meng Luo ◽  
Wen Niu ◽  
Xiangwei Ling ◽  
...  
Keyword(s):  
2020 ◽  
Vol 11 (41) ◽  
pp. 6549-6558
Author(s):  
Yohei Miwa ◽  
Mayu Yamada ◽  
Yu Shinke ◽  
Shoichi Kutsumizu

We designed a novel polyisoprene elastomer with high mechanical properties and autonomous self-healing capability at room temperature facilitated by the coexistence of dynamic ionic crosslinks and crystalline components that slowly reassembled.


1982 ◽  
Vol 118 (4) ◽  
pp. 267-272 ◽  
Author(s):  
E. Bonifazi
Keyword(s):  

1995 ◽  
Vol 131 (4) ◽  
pp. 459-461 ◽  
Author(s):  
R. Caputo
Keyword(s):  

2011 ◽  
Author(s):  
Salim Taoutaou ◽  
Jorge Andres Vargas Bermea ◽  
Pietro Bonomi ◽  
Bassam Elatrache ◽  
Christian Pasturel ◽  
...  

2020 ◽  
Author(s):  
Alexis Wolfel ◽  
Cecilia Inés Alvarez Igarzabal ◽  
Marcelo Ricardo Romero

<p>Design of materials with novel sensitivities and smart behaviour is important for the development of smart systems with automated responsiveness. We have recently reported the synthesis of hydrogels, cross-linked by <i>N,N'</i>-diallyltartardiamide (DAT). The covalent DAT-crosslinking points have vicinal diols which can be easily cleaved with periodate, generating valuable a-oxo-aldehyde functional groups, useful for further chemical modification. Based on those findings, we envisioned that a self-healable hydrogel could be obtained by incorporation of primary amino functional groups, from <a>2-aminoethyl methacrylate </a>hydrochloride (AEMA), coexisting with DAT into the same network. The a-oxo-aldehyde groups generated after the reaction with periodate would arise in the immediate environment of amine groups to form imine cross-links. For this purpose, DAT-crosslinked hydrogels were synthesized and carefully characterized. The cleavage of DAT-crosslinks with periodate promoted changes in the mechanical and swelling properties of the materials. As expected, a self-healing behavior was observed, based on the spontaneous formation of imine covalent bonds. In addition, we surprisingly found a combination of fast vicinal diols cleavage and a low speed self-crosslinking reaction by imine formation. Consequently, it was found a time-window in which a periodate-treated polymer was obtained in a transient liquid state, which can be exploited to choose the final shape of the material, before automated gelling. The singular properties attained on these hydrogels could be useful for developing sensors, actuators, among other smart systems.</p>


Sign in / Sign up

Export Citation Format

Share Document