scholarly journals Seasonal and diurnal variation of PM2.5 HULIS over Xi'an in Northwest China: Optical properties, chemical functional group, and relationship with reactive oxygen species (ROS)

2022 ◽  
Vol 268 ◽  
pp. 118782
Author(s):  
Tian Zhang ◽  
Shasha Huang ◽  
Diwei Wang ◽  
Jian Sun ◽  
Qian Zhang ◽  
...  
Pharmaceutics ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 1082
Author(s):  
Ludwig Erik Aguilar ◽  
Se Rim Jang ◽  
Chan Hee Park ◽  
Kang Min Lee

Phenolics from plant materials have garnered attention in nanomedicine research, due to their various medicinal properties. Caffeic acid, a phenolic compound that is abundant in coffee beans, has been proven to have anticancer effects, due to its reactive oxygen species (ROS)-inducing properties. Here, a supramolecular nanomedicine was designed using caffeic acid molecule and the synthetic anticancer drug bortezomib, via catechol–boronic acid conjugation and Fe(III) ion crosslinking. Bortezomib is a proteasome-inhibiting drug and its boronic acid functional group can bind to caffeic acid’s catechol moiety. By having a nanoparticle formulation that can deliver bortezomib via intracellular endocytosis, the catechol–boronic acid conjugation can be dissociated, which liberates the boronic acid functional group to bind to the 26S proteasome of the cell. The ROS-inducing property of caffeic acid also complements the bortezomib payload, as the latter suppresses the survival mechanism of the cell through NF-κB inhibition.


RSC Advances ◽  
2016 ◽  
Vol 6 (36) ◽  
pp. 30699-30709 ◽  
Author(s):  
Jun Young Kim ◽  
In Hee Lee ◽  
Daewook Kim ◽  
Seong Hwan Kim ◽  
Young-Wan Kwon ◽  
...  

Effects of reactive oxygen species on the biological and optical properties of Cordyceps pruinosa spores were studied. The decline in spore viability, antioxidative capacity, and DNA content were due to structural alteration of the cell wall.


2020 ◽  
Vol 2 (9) ◽  
pp. 4024-4033
Author(s):  
Xu Geng ◽  
Thomas R. Congdon ◽  
Palapuravan Anees ◽  
Andrea A. Greschner ◽  
Fiorenzo Vetrone ◽  
...  

This study explores chemical changes that occur to five carbon nanodots upon exposure to oxidants, and relates these to changes of their optical properties.


2009 ◽  
pp. c3 ◽  
Author(s):  
Helena M. Cochemé ◽  
Michael P. Murphy

2004 ◽  
Vol 71 ◽  
pp. 121-133 ◽  
Author(s):  
Ascan Warnholtz ◽  
Maria Wendt ◽  
Michael August ◽  
Thomas Münzel

Endothelial dysfunction in the setting of cardiovascular risk factors, such as hypercholesterolaemia, hypertension, diabetes mellitus and chronic smoking, as well as in the setting of heart failure, has been shown to be at least partly dependent on the production of reactive oxygen species in endothelial and/or smooth muscle cells and the adventitia, and the subsequent decrease in vascular bioavailability of NO. Superoxide-producing enzymes involved in increased oxidative stress within vascular tissue include NAD(P)H-oxidase, xanthine oxidase and endothelial nitric oxide synthase in an uncoupled state. Recent studies indicate that endothelial dysfunction of peripheral and coronary resistance and conductance vessels represents a strong and independent risk factor for future cardiovascular events. Ways to reduce endothelial dysfunction include risk-factor modification and treatment with substances that have been shown to reduce oxidative stress and, simultaneously, to stimulate endothelial NO production, such as inhibitors of angiotensin-converting enzyme or the statins. In contrast, in conditions where increased production of reactive oxygen species, such as superoxide, in vascular tissue is established, treatment with NO, e.g. via administration of nitroglycerin, results in a rapid development of endothelial dysfunction, which may worsen the prognosis in patients with established coronary artery disease.


2001 ◽  
Vol 120 (5) ◽  
pp. A361-A361
Author(s):  
K UCHIKURA ◽  
T WADA ◽  
Z SUN ◽  
S HOSHINO ◽  
G BULKLEY ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document