HLDnet: Novel deep learning based Artificial Intelligence tool fuses acetic acid and Lugol’s iodine cervicograms for accurate pre-cancer screening

2022 ◽  
Vol 71 ◽  
pp. 103163
Author(s):  
Ling Yan ◽  
Haoxuan Song ◽  
Yi Guo ◽  
Peng Ren ◽  
Wenhui Zhou ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Acetic Acid ◽  
Deep Learning ◽  
Cancer Screening ◽  
Lugol’S Iodine

scholarly journals Test characteristics of visual inspection with 4% acetic acid (VIA) and Lugol's iodine (VILI) in cervical cancer screening in Kerala, India

2003 ◽  
Vol 106 (3) ◽  
pp. 404-408 ◽  
Author(s):  
Rengaswamy Sankaranarayanan ◽  
Ramani Wesley ◽  
Somanathan Thara ◽  
Namrata Dhakad ◽  
Bharathykutty Chandralekha ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Acetic Acid ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Visual Inspection ◽  
Lugol’S Iodine ◽  
Test Characteristics

Implementation of a community-based cervical cancer screening program using visual inspection with acetic acid and Lugol’s iodine in Kutch District, India.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e12009-e12009
Author(s):  
Surbhi Grover ◽  
Melody Ju ◽  
Lilie L. Lin ◽  
Shobha Krishnan
Keyword(s):  
Cervical Cancer ◽  
Acetic Acid ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Visual Inspection ◽  
Screening Program ◽  
Cancer Center ◽  
Community Based ◽  
Screening Programs ◽  
Lugol’S Iodine

e12009 Background: Visual inspection with acetic acid and Lugol’s iodine (VIA/VILI) is increasingly reframed as a bridge modality through which low resource countries can provide cervical cancer screening while waiting for the more effective HPV DNA tests to become affordable. Often the screening programs are organized by government bodies that lack the trust of the local communities and hence such programs suffer from poor participation. Here we aim to describe a locally-sustained VIA/VILI screening program in rural Kutch district in India directed by Kutch Mahlia Vikas Sangathan (KMVS), a local NGO committed to women empowerment. Methods: All capacity-building measures (funding, training, materials, and healthcare workers) were rooted in the local community. Heath workers were sent to Tata Memorial Cancer Center in Mumbai for training. NGO members held information sessions prior the screening camps educating women about the significance of screening. A three-visit screening model using VIA/VILI was implemented. At first visit, all women were consented and screened. VIA/VILI positive women returned for a second visit for biospy. Biopsy positive women then returned for a third visit to arrange for treatment. All the screening camps were conducted in community buildings such as schools with the collaboration of the village leaders. Results: Screening camps were set up in 17 villages in 2010-2011, screening a total of 832 married women upto the age of 50. There were 0 cervical intraepithelial neoplasia (CIN) positive lesions or invasive cancers found. None of the women were lost to follow-up. Conclusions: It is feasible to develop a community level screening program and to provide cancer prevention needs from within a community. Future directions include further evaluation of downstream protocols after VIA/VILI tests, increasing health worker diagnostic and treatment capacity, and determining positive recruitment factors in women attending screening camps. The KMVS screening program has been well-received and has been approached by several other NGO’s and training centers seeking to build similar community-based cervical cancer screening programs.

scholarly journals Accuracy of cytology, visual inspection with acetic acid or lugol’s iodine in cervical cancer screening

1970 ◽  
Vol 2 (2) ◽  
pp. 48-53
Author(s):  
Samira Khan ◽  
Rajshree Jha ◽  
Pradam R Pant
Keyword(s):  
Cervical Cancer ◽  
Acetic Acid ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Visual Inspection ◽  
Pap Smear ◽  
Histological Evaluation ◽  
High Threshold ◽  
Lugol’S Iodine ◽  
Low Threshold

Aims: To study the accuracy of visual inspection using acetic acid (VIA) or Lugol's iodine (VILI) and Pap smear for cervical cancer screening comparing with the histology from positively screened women in all three. Method: In this descriptive study, 300 women 25 - 65 years from Gynecology clinic of T.U Teaching Hospital from December 2004 - 2005 underwent cervical screening. Positive tests for cytology was CIN I or above, VIA was opaque aceto white lesion on applying 4% acetic acid or detection of definite yellow iodine non uptake areas with Lugol's iodine in the transformation zone or close to touching the squamocolumnar junction. Positive cases were scheduled for colposcopy directed biopsies and histological evaluation. Results: Positive results obtained from cytology were 7.3% (22). VIA was positive in 52 women [low threshold +ve in 13.6% (41); high threshold +ve in 3.6%. (11)] VILI tested +ve in 8.7% (26). Cervical biopsy was done in 62 women who had positive result [10 were positive with all three tests, 4 were positive with VIA and Pap smear, 14 were positive with VIA and VILI. 24 were positive with only VIA, 2 were with only VILI and 8 were positive with only Pap smear]. Histology in 19 was suggestive of CIN and carcinoma. [LSIL (12), HSIL (6), carcinoma (1)] Pick up by Pap smear, VIA and VILI were 10; 17 and 15 missing respectively 9:[ LSIL (7) HSIL (2)]; [LSIL (2)] and 4 [LSIL (3) and HSIL (1)]. VIA had highest number of false positive as compared to Pap smear and VILI. Sensitivity for Pap smear (52.6%); low (81.1%)/high threshold VIA (80.0%) and VILI was (78.9%). Specificity for Pap smear (72 %); low was (20%) but high threshold VIA was similar to VILI (74.4%) The positive predictive value of low or high threshold VIA, VILI and cytology were 22.0%, 72.7%, 57.7% and 45.5%; such that the compounding NPV were 80.0%, 80.0%, 88.9% 77.5%. Overall accuracy of high threshold VIA (76 %) was comparable to VILI 75.8%; cytology having 66% and low threshold VIA with 33 %. Conclusion: High threshold VIA and VILI have higher accuracy for detection of precancerous lesions of cervix than Pap smear indicating that these test to be implicated for cancer screening which is more cost effective. Keywords: Visual inspection; acetic acid; Lugol's iodine; VIA; VILI; screening of cervical cancer; Papanicolau (Pap) smear. doi:10.3126/njog.v2i2.1455 N. J. Obstet. Gynaecol 2007 Nov-Dec; 2 (2): 48 - 53

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