Minor Myocardial Damage is a Prevalent Condition in Patients With Acute Heart Failure Syndromes and Preserved Systolic Function With Long-Term Prognostic Implications. A Report From the CIAST-HF (Collaborative Italo-Argentinean Study on Cardiac Troponin T in Heart Failure) Study

2012 ◽  
Vol 18 (11) ◽  
pp. 822-830 ◽  
Author(s):  
Eduardo R. Perna ◽  
Nadia Aspromonte ◽  
Juan P. Cimbaro Canella ◽  
Giuseppe Di Tano ◽  
Stella M. Macin ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Systolic Function ◽  
Myocardial Damage ◽  
Cardiac Troponin T ◽  
Acute Heart Failure Syndromes ◽  
Prognostic Implications ◽  
Minor Myocardial Damage

Minor myocardial damage detected by troponin T is a powerful predictor of long-term prognosis in patients with acute decompensated heart failure

2005 ◽  
Vol 99 (2) ◽  
pp. 253-261 ◽  
Author(s):  
Eduardo R. Perna ◽  
Stella M. Macı́n ◽  
Juan P. Cimbaro Canella ◽  
Pablo M. Alvarenga ◽  
Nelson G. Rı́os ◽  
...  
Keyword(s):  
Heart Failure ◽  
Troponin T ◽  
Acute Decompensated Heart Failure ◽  
Myocardial Damage ◽  
Decompensated Heart Failure ◽  
Powerful Predictor ◽  
Long Term Prognosis ◽  
Minor Myocardial Damage

scholarly journals Prognostic Value of Combination of Cardiac Troponin T and B-Type Natriuretic Peptide after Initiation of Treatment in Patients with Chronic Heart Failure

2003 ◽  
Vol 49 (12) ◽  
pp. 2020-2026 ◽  
Author(s):  
Junnichi Ishii ◽  
Wei Cui ◽  
Fumihiko Kitagawa ◽  
Takahiro Kuno ◽  
Yuu Nakamura ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Myocardial Damage ◽  
Left Ventricular ◽  
Functional Class ◽  
Cardiac Troponin T ◽  
Cardiac Events ◽  
Nyha Functional Class

Abstract Background: Recent studies have suggested that cardiac troponin T (cTnT) and troponin I may detect ongoing myocardial damage involved in the progression of chronic heart failure (CHF). This study was prospectively designed to examine whether the combination of cTnT, a marker for ongoing myocardial damage, and B-type natriuretic peptide (BNP), a marker for left ventricular overload, would effectively stratify patients with CHF after initiation of treatment. Methods: We measured serum cTnT, plasma BNP, and left ventricular ejection fraction (LVEF) on admission for worsening CHF [New York Heart Association (NYHA) functional class III to IV] and 2 months after initiation of treatment to stabilize CHF (n = 100; mean age, 68 years). Results: Mean (SD) concentrations of cTnT [0.023 (0.066) vs 0.063 (0.20) μg/L] and BNP [249 (276) vs 753 (598) ng/L], percentage increased cTnT (>0.01 μg/L; 35% vs 60%), NYHA functional class [2.5 (0.6) vs 3.5 (5)], and LVEF [43 (13)% vs 36 (12)%] were significantly (P <0.01) improved 2 months after treatment compared with admission. During a mean follow-up of 391 days, there were 44 cardiac events, including 12 cardiac deaths and 32 readmissions for worsening CHF. On a stepwise Cox regression analysis, increased cTnT and BNP were independent predictors of cardiac events (P <0.001). cTnT >0.01 μg/L and/or BNP >160 ng/L 2 months after initiation of treatment were associated with increased cardiac mortality and morbidity rates. Conclusion: The combination of cTnT and BNP measurements after initiation of treatment may be highly effective for risk stratification in patients with CHF.

Elevated Cardiac Troponin T (cTnT) in the Extreme Elderly Group of Patients: The Short and Long Term Prognostic Implications

2010 ◽  
Vol 19 ◽  
pp. S216
Author(s):  
T. Nguyen ◽  
J. Gohil ◽  
D. Leung ◽  
G. Le ◽  
J. French ◽  
...  
Keyword(s):  
Cardiac Troponin ◽  
Troponin T ◽  
Elderly Group ◽  
Cardiac Troponin T ◽  
Short And Long Term ◽  
Prognostic Implications

Increased levels of cardiac troponin-T in outpatients with heart failure and preserved systolic function are related to adverse clinical findings and outcome

2006 ◽  
Vol 17 (8) ◽  
pp. 685-691 ◽  
Author(s):  
Stella M. Macin ◽  
Eduardo R. Perna ◽  
Juan P. Cimbaro Canella ◽  
Natalia Augier ◽  
Jorge L. Riera Stival ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Systolic Function ◽  
Clinical Findings ◽  
Cardiac Troponin T

P-59 In Patients with Heart Failure, Cardiac Troponin T Is a Reliable Predictor of Long-Term Echocardiographic Changes and Adverse Cardiac Events

2009 ◽  
Vol 4 ◽  
pp. S68
Author(s):  
Kiyoto Nishi ◽  
Yukihito Sato ◽  
Tadashi Miyamoto ◽  
Ryoji Taniguchi ◽  
Rei Fukuhara ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Cardiac Troponin T ◽  
Cardiac Events ◽  
Reliable Predictor ◽  
Adverse Cardiac Events ◽  
Patients With Heart Failure
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