Nutrition-related problems, nutritional support practices and barriers to adherence to nutritional guidelines during intensive treatment for acute myeloid leukemia: patients’ and hematology nurses’ perspectives and experiences

Author(s):  
Rianne van Lieshout ◽  
Nora Lize ◽  
Lidwine W. Tick ◽  
Judith van Deursen ◽  
Eline Driessen ◽  
...  
Leukemia ◽  
2018 ◽  
Vol 32 (7) ◽  
pp. 1621-1630 ◽  
Author(s):  
Peter Paschka ◽  
Richard F Schlenk ◽  
Daniela Weber ◽  
Axel Benner ◽  
Lars Bullinger ◽  
...  

2020 ◽  
Author(s):  
Zuzana Sustkova ◽  
Lukas Semerad ◽  
Barbora Weinbergerova ◽  
Jiri Mayer

Blood ◽  
2009 ◽  
Vol 113 (18) ◽  
pp. 4179-4187 ◽  
Author(s):  
Gunnar Juliusson ◽  
Petar Antunovic ◽  
Åsa Derolf ◽  
Sören Lehmann ◽  
Lars Möllgård ◽  
...  

AbstractAcute myeloid leukemia (AML) is most common in the elderly, and most elderly are thought to be unfit for intensive treatment because of the risk of fatal toxicity. The Swedish Acute Leukemia Registry covers 98% of all patients with AML (nonacute promyelocytic leukemia) diagnosed in 1997 to 2005 (n = 2767), with a median follow-up of 5 years, and reports eligibility for intensive therapy, performance status (PS), complete remission rates, and survival. Outcomes were strongly age and PS dependent. Early death rates were always lower with intensive therapy than with palliation only. Long-term survivors were found among elderly given intensive treatment despite poor initial PS. Total survival of elderly AML patients was better in the geographic regions where most of them were given standard intensive therapy. This analysis provides unique real world data from a large, complete, and unselected AML population, both treated and untreated, and gives background to treatment decisions for the elderly. Standard intensive treatment improves early death rates and long-term survival compared with palliation. Most AML patients up to 80 years of age should be considered fit for intensive therapy, and new therapies must be compared with standard induction.


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