Neurocognitive characteristics of youth with noncomorbid and comorbid forms of conduct disorder and attention deficit hyperactivity disorder

2017 ◽  
Vol 77 ◽  
pp. 60-70 ◽  
Author(s):  
Andrea L. Glenn ◽  
Rheanna J. Remmel ◽  
Min Yee Ong ◽  
Nikki S.J. Lim ◽  
Rebecca P. Ang ◽  
...  
2014 ◽  
Vol 55 (4) ◽  
pp. 328-336 ◽  
Author(s):  
Holly E. Erskine ◽  
Alize J. Ferrari ◽  
Guilherme V. Polanczyk ◽  
Terrie E. Moffitt ◽  
Christopher J. L. Murray ◽  
...  

2004 ◽  
Vol 34 (6) ◽  
pp. 1113-1127 ◽  
Author(s):  
M. C. MONUTEAUX ◽  
G. FITZMAURICE ◽  
D. BLACKER ◽  
S. L. BUKA ◽  
J. BIEDERMAN

Background. To examine the familial associations of overt and covert antisocial behavior within the diagnosis of conduct disorder (CD) in families ascertained by referred children with attention-deficit hyperactivity disorder (ADHD), and to test if these familial associations differed between male and female probands.Method. Subjects were clinically-referred male and female ADHD children (n=273) and their first-degree biological relatives (n=807). Scores for overt and covert conduct problems were calculated by summing the DSM-III-R conduct disorder symptoms, as derived from structured diagnostic interviews. Familial aggregation analyses were conducted with multivariate regression modeling methodology.Results. Proband overt scores significantly predicted the overt scores of their relatives, and proband covert scores significantly predicted the covert scores of their relatives. There was no evidence of covert symptom scores predicting overt scores or vice versa. There was some evidence that the aggregation of covert symptoms was stronger in the families of female probands.Conclusions. These results provide preliminary evidence that overt and covert conduct disorder symptoms are independently transmitted through families and may represent distinct familial syndromes.


2017 ◽  
Author(s):  
Paul Croarkin ◽  
Reem Shafi

Oppositional defiant disorder (ODD) is a psychiatric disorder classified in the DSM-5 among disruptive, impulse control, and conduct disorder. The core features of ODD include a pervasive and impairing pattern of anger, irritability, inflexibility, defiance, malevolence, and aggression. Symptoms of ODD typically present during preschool. ODD can be a harbinger of conduct disorder. Isolated, transient symptoms of ODD are normal during development. Mood disorders, attention-deficit/hyperactivity disorder, and neurodevelopmental disorders are important considerations in differential diagnosis. However, ODD frequently co-occurs with other psychiatric diagnoses. Complex interactions with temperamental emotional dysregulation, family stress, early life stress, inconsistent parenting, and genetic and physiologic factors likely underlie the risk, pathophysiology, and prognosis of ODD. Unfortunately, these interactions and the neurobiological underpinnings of ODD are still poorly characterized. Although first-line treatments for ODD involve behavioral and psychosocial interventions, a thoughtful consideration of pharmacotherapy for co-occurring disorders and severe symptoms is an important component of treatment planning. Herein we review the epidemiology, etiology, pathophysiology, diagnostic evaluation, and treatment planning of ODD. Recent applicable controversies such as dimensional conceptualization of psychiatric disorders and the potential intersection of ODD and disruptive mood dysregulation disorder are also summarized.  This review contains 5 figures, 4 tables, and 44 references. Key words: aggression, attention-deficit/hyperactivity disorder, conduct disorder, defiance, disruptive behaviors, disruptive mood dysregulation disorder, DSM-5, irritability, oppositional defiant disorder, parent management training


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