Maintenance therapy of patients with recurrent epithelial ovarian carcinoma with the anti-tumor-associated-mucin-1 antibody gatipotuzumab: results from a double-blind, placebo-controlled, randomized, phase II study

J.A. Ledermann; B. Zurawski; F. Raspagliesi; U. De Giorgi; J. Arranz Arija; M. Romeo Marin; A. Lisyanskaya; R.L. Póka; J. Markowska; C. Cebotaru; A. Casado Herraez; N. Colombo; E. Kutarska; M. Hall; A. Jacobs; I. Ahrens-Fath; H. Baumeister; A. Zurlo; J. Sehouli

doi:10.1016/j.esmoop.2021.100311

Maintenance therapy of patients with recurrent epithelial ovarian carcinoma with the anti-tumor-associated-mucin-1 antibody gatipotuzumab: results from a double-blind, placebo-controlled, randomized, phase II study

ESMO Open ◽

10.1016/j.esmoop.2021.100311 ◽

2022 ◽

Vol 7 (1) ◽

pp. 100311

Author(s):

J.A. Ledermann ◽

B. Zurawski ◽

F. Raspagliesi ◽

U. De Giorgi ◽

J. Arranz Arija ◽

...

Keyword(s):

Maintenance Therapy ◽

Ovarian Carcinoma ◽

Phase Ii ◽

Phase Ii Study ◽

Epithelial Ovarian Carcinoma ◽

Mucin 1 ◽

Double Blind ◽

Double Blind Placebo ◽

Randomized Phase Ii

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38 Influence of amifostine on neuroprotection in 1st-line treatment of advanced ovarian cancer with carboplatin/taxane-based chemotherapy - a double-blind, placebo-controlled, randomized phase II-study from the AGO Ovarian Cancer Study Group

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(03)90072-3 ◽

2003 ◽

Vol 1 (5) ◽

pp. S15-S16

Author(s):

P. Wimberger ◽

R. Kimmig ◽

F. Hilpert ◽

A. Stähle ◽

A. Burges ◽

...

Keyword(s):

Ovarian Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Advanced Ovarian Cancer ◽

Study Group ◽

Line Treatment ◽

Double Blind ◽

Double Blind Placebo ◽

Cancer Study Group ◽

Randomized Phase Ii

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Double-blind, placebo-controlled, randomized phase II study of TJ-14 (Hangeshashinto) for infusional fluorinated-pyrimidine-based colorectal cancer chemotherapy-induced oral mucositis

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-015-2767-y ◽

2015 ◽

Vol 76 (1) ◽

pp. 97-103 ◽

Cited By ~ 34

Author(s):

Chu Matsuda ◽

Yoshinori Munemoto ◽

Hideyuki Mishima ◽

Naoki Nagata ◽

Mitsuru Oshiro ◽

...

Keyword(s):

Colorectal Cancer ◽

Phase Ii ◽

Cancer Chemotherapy ◽

Oral Mucositis ◽

Phase Ii Study ◽

Double Blind ◽

Double Blind Placebo ◽

Randomized Phase Ii

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Randomized, double-blind, placebo-controlled phase II study of AMG 386 combined with weekly paclitaxel in patients (pts) with recurrent ovarian carcinoma.

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.15_suppl.5000 ◽

2010 ◽

Vol 28 (15_suppl) ◽

pp. 5000-5000 ◽

Cited By ~ 20

Author(s):

B. Y. Karlan ◽

A. M. Oza ◽

V. L. Hansen ◽

G. E. Richardson ◽

D. M. Provencher ◽

...

Keyword(s):

Ovarian Carcinoma ◽

Phase Ii ◽

Phase Ii Study ◽

Weekly Paclitaxel ◽

Double Blind ◽

Double Blind Placebo ◽

Amg 386

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Double-blind, placebo-controlled, randomized, phase 2 study to evaluate the efficacy and safety of maintenance therapy with anti-TA-MUC1 monoclonal antibody PankoMab after chemotherapy in patients with recurrent epithelial ovarian carcinoma.

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.tps5622 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. TPS5622-TPS5622

Author(s):

Jonathan A. Ledermann ◽

Ingo von Broen ◽

Frank Zimmermann ◽

Johannes Nippgen ◽

Steffen Goletz

Keyword(s):

Monoclonal Antibody ◽

Maintenance Therapy ◽

Ovarian Carcinoma ◽

Epithelial Ovarian Carcinoma ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Study ◽

Randomized Phase 2

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A randomized, double-blind, placebo-controlled phase II study of maintenance therapy with tasquinimod in patients with metastatic castration-resistant prostate cancer responsive to or stabilized during first-line docetaxel chemotherapy

Annals of Oncology ◽

10.1093/annonc/mdx487 ◽

2017 ◽

Vol 28 (11) ◽

pp. 2741-2746 ◽

Cited By ~ 7

Author(s):

K. Fizazi ◽

A. Ulys ◽

L. Sengeløv ◽

M. Moe ◽

S. Ladoire ◽

...

Keyword(s):

Prostate Cancer ◽

Maintenance Therapy ◽

Phase Ii ◽

Phase Ii Study ◽

Castration Resistant Prostate Cancer ◽

First Line ◽

Double Blind ◽

Double Blind Placebo ◽

Castration Resistant ◽

Docetaxel Chemotherapy

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Intraperitoneal Bevacizumab (Bev) for Control of Malignant Ascites Due to Advanced-Stage Gastrointestinal Cancers (Gi): a Multicenter Double-Blind, Placebo (Pl)-Controlled, Randomized Phase Ii Study. Aio Sup-0108

Annals of Oncology ◽

10.1093/annonc/mdu356.8 ◽

2014 ◽

Vol 25 ◽

pp. iv520

Author(s):

K. Jordan ◽

D. Atanackovic ◽

C. Gog ◽

B. Killing ◽

M. Stahl ◽

...

Keyword(s):

Phase Ii ◽

Phase Ii Study ◽

Malignant Ascites ◽

Advanced Stage ◽

Gastrointestinal Cancers ◽

Double Blind ◽

Double Blind Placebo ◽

Randomized Phase Ii

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Double-Blind, Placebo-Controlled, Randomized Phase II Study of TJ-14 (Hangeshashinto) for Infusional Fluorinated-Pyrimidine-based Colorectal Cancer Chemotherapy-induced Oral Mucositis

Annals of Cancer Research and Therapy ◽

10.4993/acrt.21.26 ◽

2013 ◽

Vol 21 (1) ◽

pp. 26-30 ◽

Cited By ~ 1

Author(s):

Chu Matsuda ◽

Toru Kono ◽

Yoshinori Munemoto ◽

Naoki Nagata ◽

Masato Kataoka ◽

...

Keyword(s):

Colorectal Cancer ◽

Phase Ii ◽

Cancer Chemotherapy ◽

Oral Mucositis ◽

Phase Ii Study ◽

Double Blind ◽

Double Blind Placebo ◽

Randomized Phase Ii

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Double-Blind, Placebo-Controlled, Multicenter, Randomized, Phase Ii Study of Nimotuzumab in Combination with Mitomycin, 5-Fluorouracil and Radiation in Immunocompetent Patients with Anal Carcinoma

Annals of Oncology ◽

10.1093/annonc/mdu333.115 ◽

2014 ◽

Vol 25 ◽

pp. iv209

Author(s):

U. Pérez González ◽

F.F. Llorente Llano ◽

M. Ramos Suzarte ◽

J.E. Rodríguez Reigosa ◽

B.F. Mestre Fernández ◽

...

Keyword(s):

Phase Ii ◽

Phase Ii Study ◽

Anal Carcinoma ◽

Double Blind ◽

Double Blind Placebo ◽

Randomized Phase Ii ◽

Immunocompetent Patients

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Double-blind, placebo-controlled, randomized phase II study of TJ-14 (hangeshashinto) for gastric cancer chemotherapy-induced oral mucositis

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-014-2440-x ◽

2014 ◽

Vol 73 (5) ◽

pp. 1047-1054 ◽

Cited By ~ 25

Author(s):

Toru Aoyama ◽

Kazuhiro Nishikawa ◽

Nobuhiro Takiguchi ◽

Kazuaki Tanabe ◽

Motohiro Imano ◽

...

Keyword(s):

Gastric Cancer ◽

Phase Ii ◽

Cancer Chemotherapy ◽

Oral Mucositis ◽

Phase Ii Study ◽

Double Blind ◽

Double Blind Placebo ◽

Randomized Phase Ii

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A double-blind, placebo-controlled, randomized, phase 2 study to evaluate the efficacy and safety of switch maintenance therapy with the anti-TA-MUC1 antibody PankoMab-GEX after chemotherapy in patients with recurrent epithelial ovarian carcinoma

Annals of Oncology ◽

10.1093/annonc/mdx440.035 ◽

2017 ◽

Vol 28 ◽

pp. v626 ◽

Cited By ~ 6

Author(s):

J. Ledermann ◽

J. Sehouli ◽

B. Zurawski ◽

F. Raspagliesi ◽

U. De Giorgi ◽

...

Keyword(s):

Maintenance Therapy ◽

Ovarian Carcinoma ◽

Epithelial Ovarian Carcinoma ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Study ◽

Switch Maintenance Therapy ◽

Randomized Phase 2

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