Exploring the relationship between the gut microbiome and mental health outcomes in a posttraumatic stress disorder cohort relative to trauma-exposed controls

2022 ◽  
Vol 56 ◽  
pp. 24-38
Author(s):  
Stefanie Malan-Muller ◽  
Mireia Valles-Colomer ◽  
Christine L. Foxx ◽  
Sara Vieira-Silva ◽  
Leigh L. van den Heuvel ◽  
...  
Keyword(s):  
Mental Health ◽  
Posttraumatic Stress Disorder ◽  
Health Outcomes ◽  
Posttraumatic Stress ◽  
Gut Microbiome ◽  
Stress Disorder ◽  
Mental Health Outcomes ◽  
The Relationship

scholarly journals Posttraumatic stress disorder and depression of survivors 12 months after the outbreak of Middle East Respiratory Syndrome in South Korea

2020 ◽  
Author(s):  
Hye Yoon Park ◽  
Wan Beom Park ◽  
So Hee Lee ◽  
Jeong Lan Kim ◽  
Jung Jae Lee ◽  
...  
Keyword(s):  
Mental Health ◽  
Posttraumatic Stress Disorder ◽  
Middle East ◽  
Health Outcomes ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Physical Symptoms ◽  
Middle East Respiratory Syndrome ◽  
Mental Health Outcomes

Abstract Background: The 2015 outbreak of Middle East Respiratory Syndrome (MERS) in the Republic of Korea is a recent and representative occurrence of nationwide outbreaks of Emerging Infectious Diseases (EIDs). In addition to physical symptoms, posttraumatic stress disorder (PTSD) and depression are common following outbreaks of EID.Methods: The present study investigated the long-term mental health outcomes and related risk factors in survivors of MERS. A prospective nationwide cohort study was conducted 12 months after the MERS outbreak at multi-centers throughout Korea. PTSD and depression as the main mental health outcomes were assessed with the Impact of Event Scale-Revised Korean version (IES-R-K) and the Patient Health Questionnaire-9 (PHQ-9) respectively.Results: 42.9% of survivors reported PTSD (IES-R-K ≥ 25) and 27.0% reported depression (PHQ-9 ≥ 10) at 12 months post-MERS. A multivariate analysis revealed that anxiety (adjusted odds ratio [aOR], 5.76; 95%CI, 1.29–25.58; P = 0.021), and a greater recognition of stigma (aOR, 11.09, 95%CI, 2.28–53.90; P = 0.003) during the MERS-affected period were independent predictors of PTSD at 12 months after the MERS outbreak. Having a family member who died from MERS predicted the development of depression (aOR, 12.08, 95%CI, 1.47–99.19; P = 0.020).Conclusion: This finding implies that psychosocial factors, particularly during the outbreak phase, influenced the mental health of patients over a long-term period. Mental health support among the infected subjects and efforts to reduce stigma may improve recovery from psychological distress in an EID outbreak.

scholarly journals Posttraumatic stress disorder and depression of survivors 12 months after the outbreak of Middle East Respiratory Syndrome in South Korea

2020 ◽  
Author(s):  
Hye Yoon Park ◽  
Wan Beom Park ◽  
So Hee Lee ◽  
Jeong Lan Kim ◽  
Jung Jae Lee ◽  
...  
Keyword(s):  
Mental Health ◽  
Posttraumatic Stress Disorder ◽  
Middle East ◽  
Health Outcomes ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Physical Symptoms ◽  
Middle East Respiratory Syndrome ◽  
Mental Health Outcomes

Abstract Background: The 2015 outbreak of Middle East Respiratory Syndrome (MERS) in the Republic of Korea is a recent and representative occurrence of nationwide outbreaks of Emerging Infectious Diseases (EIDs) . In addition to physical symptoms, posttraumatic stress disorder (PTSD) and depression are common following outbreaks of EID. Methods: The present study investigated the long-term mental health outcomes and related risk factors in survivors of MERS. A prospective nationwide cohort study was conducted 12 months after the MERS outbreak at multi-centers throughout Korea. PTSD and depression as the main mental health outcomes were assessed with the Impact of Event Scale-Revised Korean version (IES-R-K) and the Patient Health Questionnaire-9 (PHQ-9) respectively. Results: 42.9% of survivors reported PTSD (IES-R-K ≥ 25) and 27.0% reported depression (PHQ-9 ≥ 10) at 12 months post-MERS. A multivariate analysis revealed that anxiety (adjusted odds ratio [aOR], 5.76; 95%CI, 1.29–25.58; P = 0.021), and a greater recognition of stigma (aOR, 11.09, 95%CI, 2.28–53.90; P = 0.003) during the MERS-affected period were independent predictors of PTSD at 12 months after the MERS outbreak. Having a family member who died from MERS predicted the development of depression (aOR, 12.08, 95%CI, 1.47–99.19; P = 0.020). Conclusion: This finding implies that psychosocial factors, particularly during the outbreak phase, influenced the mental health of patients over a long-term period. Mental health support among the infected subjects and efforts to reduce stigma may improve recovery from psychological distress in an EID outbreak.

scholarly journals Posttraumatic stress disorder and depression of survivors 12 months after the outbreak of Middle East Respiratory Syndrome in South Korea

2020 ◽  
Author(s):  
Hye Yoon Park ◽  
Wan Beom Park ◽  
So Hee Lee ◽  
Jeong Lan Kim ◽  
Jung Jae Lee ◽  
...  
Keyword(s):  
Mental Health ◽  
Posttraumatic Stress Disorder ◽  
Middle East ◽  
Health Outcomes ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Physical Symptoms ◽  
Middle East Respiratory Syndrome ◽  
Mental Health Outcomes

Abstract Background: The 2015 outbreak of Middle East Respiratory Syndrome (MERS) in the Republic of Korea is a recent and representative occurrence of nationwide outbreaks of Emerging Infectious Diseases (EIDs) . In addition to physical symptoms, posttraumatic stress disorder (PTSD) and depression are common following outbreaks of EID. Methods: The present study investigated the long-term mental health outcomes and related risk factors in survivors of MERS. A prospective nationwide cohort study was conducted 12 months after the MERS outbreak at multi-centers throughout Korea. PTSD and depression as the main mental health outcomes were assessed with the Impact of Event Scale-Revised Korean version (IES-R-K) and the Patient Health Questionnaire-9 (PHQ-9) respectively. Results: 42.9% of survivors reported PTSD (IES-R-K ≥ 25) and 27.0% reported depression (PHQ-9 ≥ 10) at 12 months post-MERS. A multivariate analysis revealed that anxiety (adjusted odds ratio [aOR], 5.76; 95%CI, 1.29–25.58; P = 0.021), and a greater recognition of stigma (aOR, 11.09, 95%CI, 2.28–53.90; P = 0.003) during the MERS-affected period were independent predictors of PTSD at 12 months after the MERS outbreak. Having a family member who died from MERS predicted the development of depression (aOR, 12.08, 95%CI, 1.47–99.19; P = 0.020). Conclusion: This finding implies that psychosocial factors, particularly during the outbreak phase, influenced the mental health of patients over a long-term period. Mental health support among the infected subjects and efforts to reduce stigma may improve recovery from psychological distress in an EID outbreak.

Age moderates the relationship between source of social support and mental health in racial minority lesbian, gay, and bisexual youth

2017 ◽  
Vol 24 (7) ◽  
pp. 888-897
Author(s):  
Anna E Wise ◽  
Brian C Smith ◽  
Aaron P Armelie ◽  
Jessica M Boarts ◽  
Douglas L Delahanty
Keyword(s):  
Mental Health ◽  
Social Support ◽  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Low Socioeconomic Status ◽  
Stress Disorder ◽  
Racial Minority ◽  
Depression Symptoms ◽  
And Bisexual ◽  
The Relationship

We examined the relationship between source of social support and mental health (and the moderating impact of age) in 64 low socioeconomic status, racial minority lesbian, gay, and bisexual adolescents/young adults. Social support from family ( β = −.302, p = .03; β = −.364, p = .008), but not friends or significant others, was independently related to posttraumatic stress disorder and depression symptoms, respectively. Family social support was associated with lower posttraumatic stress disorder and depression symptoms in participants aged 16–19 years, while friend social support was associated with lower symptoms for participants aged over 20 years. Friend social support was also associated with lower posttraumatic stress disorder symptoms in participants aged 16–17 years. Interventions should target age-appropriate sources of social support.

scholarly journals The role of social support in the relationship between mental health and posttraumatic stress disorder amongst orthopaedic patients

Curationis ◽  
2013 ◽  
Vol 36 (1) ◽  
Author(s):  
Vhuhwavho M. Maselesele ◽  
Erhabor S. Idemudia
Keyword(s):  
Mental Health ◽  
Social Support ◽  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Significant Relationship ◽  
Stress Disorder ◽  
Perceived Social Support ◽  
Orthopaedic Trauma ◽  
Orthopaedic Patients ◽  
The Relationship

Background: Some life-event experiences such as injuries in car accidents, gun shots and the like, can be life changing and traumatic. Objectives: The article investigated the relationship between mental health and posttraumatic stress disorder (PTSD) symptoms after orthopaedic trauma, and attempted to understand whether social support moderates the relationship between mental health and PTSD.Method: A cross-sectional research model was used. Two hundred participants were selected using simple randomisation within a hospital complex in Gauteng, South Africa. The sample consisted of 110 men and 90 women (x̄ = 37.8 years, s.d. = 12.9 years). Data were collected using the Revised Civilian Mississippi Scale for PTSD, the Multidimensional Scale of Perceived Social Support (MSPSS), and the General Health Questionnaire version 28.Results: The findings of the study indicated that there is a statistically significant relationship between mental health and PTSD after orthopaedic trauma, and a positive correlation between poor mental health and PTSD (r = 0.52, n = 200, p < 0.05). However, perceived social support did not moderate mental health or PTSD, indicating that perceived social support did not significantly influence mental health or PTSD, (MSPSS B = 0.07, p = 0.66). Those with high scores on social support had a lower regression coefficient (B = 0.19) for mental health and PTSD than those who reported low social support (B = 0.26).Conclusion: There is a significant relationship between mental health and PTSD of orthopaedic patients, and social support did not moderate the relationship between mental health and PTSD. 

scholarly journals Food insecurity is associated with anxiety, stress, and symptoms of posttraumatic stress disorder in a cohort of women with or at risk of HIV in the United States

2019 ◽  
Vol 149 (8) ◽  
pp. 1393-1403 ◽  
Author(s):  
Henry J Whittle ◽  
Lila A Sheira ◽  
William R Wolfe ◽  
Edward A Frongillo ◽  
Kartika Palar ◽  
...  
Keyword(s):  
Mental Health ◽  
United States ◽  
At Risk ◽  
Posttraumatic Stress Disorder ◽  
Food Security ◽  
Health Outcomes ◽  
Food Insecurity ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
The United States

ABSTRACT Background Food insecurity, which disproportionately affects marginalized women in the United States, is associated with depressive symptoms. Few studies have examined relations of food insecurity with other mental health outcomes. Objective The aim of this study was to investigate the associations of food insecurity with symptoms of generalized anxiety disorder (GAD), stress, and posttraumatic stress disorder (PTSD) in the Women's Interagency HIV Study (WIHS), a prospective cohort study of women with or at risk of HIV in the United States. Methods Participants were 2553 women with or at risk of HIV, predominantly African American/black (71.6%). Structured questionnaires were conducted during April 2013–March 2016 every 6 mo. Food security (FS) was the primary predictor, measured using the Household Food Security Survey Module. We measured longitudinal outcomes for GAD (GAD-7 score and a binary GAD-7 screener for moderate-to-severe GAD). Only cross-sectional data were available for outcomes measuring perceived stress (PSS-10 score) and PTSD (PCL-C score and a binary PCL-C screener for PTSD). We examined associations of FS with the outcomes through use of multivariable linear and logistic regression, including lagged associations with GAD outcomes. Results After adjusting for sociodemographic and health-related factors including HIV serostatus, current marginal, low, and very low FS were associated with increasingly higher GAD-7 scores, and with 1.41 (95% CI: 1.10, 1.80; P < 0.01), 2.03 (95% CI: 1.59, 2.61; P < 0.001), and 3.23 (95% CI: 2.43, 4.29; P < 0.001) times higher odds of screening positive for moderate-to-severe GAD, respectively. Low and very low FS at the previous visit (6 mo earlier) were independently associated with GAD outcomes at current visit. Associations of FS with PSS-10 and PCL-C scores exhibited similar dose-response relations. Very low FS was associated with 1.93 (95% CI: 1.15, 3.24; P < 0.05) times higher odds of screening positive for PTSD. Conclusions Food insecurity may be associated with a range of poor mental health outcomes among women in the United States with or at risk of HIV.

Social Support, Emotional Intelligence, and Posttraumatic Stress Disorder Symptoms

2016 ◽  
Vol 37 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Nicole L. Hofman ◽  
Austin M. Hahn ◽  
Christine K. Tirabassi ◽  
Raluca M. Gaher
Keyword(s):  
Social Support ◽  
Posttraumatic Stress Disorder ◽  
Emotional Intelligence ◽  
Protective Factors ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Traumatic Events ◽  
Ptsd Symptoms ◽  
The Relationship

Abstract. Exposure to traumatic events and the associated risk of developing Posttraumatic stress disorder (PTSD) symptoms is a significant and overlooked concern in the college population. It is important for current research to identify potential protective factors associated with the development and maintenance of PTSD symptoms unique to this population. Emotional intelligence and perceived social support are two identified protective factors that influence the association between exposure to traumatic events and PTSD symptomology. The current study examined the mediating role of social support in the relationship between emotional intelligence and PTSD symptoms. Participants included 443 trauma-exposed university students who completed online questionnaires. The results of this study indicated that social support mediates the relationship between emotional intelligence and reported PTSD symptoms. Thus, emotional intelligence is significantly associated with PTSD symptoms and social support may play an integral role in the relationship between emotional intelligence and PTSD. The current study is the first to investigate the role of social support in the relationship between emotional intelligence and PTSD symptoms. These findings have important treatment and prevention implications with regard to PTSD.

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