A case report highlights the neglect problem of pregnancy denial

Pregnancy denial was observed in a patient after her second delivery. Contrary to the first pregnancy, she denied weight gain, body changes and baby movements. She reported using a contraceptive pill throughout the entire pregnancy. After a short home delivery without assistance, she was admitted to obstetrical department and referred for psychiatric evaluation. Mrs. T. accepted psychiatric follow-up appointments and was followed up for 6 months. She was initially assessed using the SCID II Interview, beck anxiety and depression interview, WHOQOL (WHO quality of life), and childhood trauma questionnaire. She denied pregnancy concealment and during the period of assessment and follow-up there was no evidence of intimate partner violence. Her female newborn was healthy without consequences of oestrogen/progesteron absorption (hypoplastic left heart syndrome, gastroschisis, hypospadias or congenital urinary trait anomalies) in one year follow up. The patient was discharged after 6 months of clinical outpatient follow-up. This case stresses and emphasizes the health and risk outcomes for both mother and child linked to an underestimated but serious phenomenon such as the denial of pregnancy.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Epigenetics in the Remission of Anorexia Nervosa: A Follow-up Study of Whole-genome Methylation Profiles

European Psychiatry ◽

10.1016/j.eurpsy.2017.01.316 ◽

2017 ◽

Vol 41 (S1) ◽

pp. S102-S102 ◽

Cited By ~ 1

Author(s):

N. Ramoz ◽

S. Guillaume ◽

P. Courtet ◽

P. Gorwood

Keyword(s):

Anorexia Nervosa ◽

Whole Genome ◽

Biological Processes ◽

Methylation Of Dna ◽

Genome Methylation ◽

The Difference ◽

Competing Interest ◽

One Year ◽

Epigenetic Signatures

IntroductionAnorexia nervosa (AN) is a severe psychiatric disorder. The epigenetic regulations are strongly suggested in AN. We and other groups have performed a whole-genome methylation study (methylome) in AN. We found that the differentially methylated CpG sites are located around genes involved in biological processes in link with embryonic morphogenesis, brain development and its plasticity, in particular adhesion and axon guidance. Here, we study an independent group of 40 AN patients. Furthermore, we have done a follow-up during more than one year, to compare the methylation profiles in subjects that evolve to the remission.ObjectivesOur work is to replicate the methylome study in an independent AN cohort and to characterize profiles of methylation at two times for the same subjects to compare the AN patients that convert to remitters.AimsOur goal is to identify diagnostic and prognostic epigenetic signatures for AN.MethodsOf the 40 AN patients, 18 evolved to remission. Furthermore, the blood samples of the subjects from the 2 times will be investigated, like this, each subject is its own control. Methylation of DNA is measured by using the Infinium HumanMethylation450 BeadChip technology.ResultsComparisons of AN to controls showed similar profiles of methylation involving the same biological processes as previously identified. We are comparing now the difference of methylation between the 18 remitters and the 18 actual AN, taking into account of the two times of samples.ConclusionsWe expect to characterize specific methylation signature of the prognostic of the AN remission.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Eating Disorders and Sexuality: A Complex Relationship

European Psychiatry ◽

10.1016/j.eurpsy.2017.01.170 ◽

2017 ◽

Vol 41 (S1) ◽

pp. S36-S37

Author(s):

V. Ricca ◽

G. Castellini ◽

L. Lelli ◽

F. Rotella ◽

A.M. Monteleone ◽

...

Keyword(s):

Eating Disorders ◽

Sexual Function ◽

Sexual Functioning ◽

Recovery Process ◽

Behavioural Therapy ◽

Eating Disorder Examination ◽

Regular Menses ◽

Competing Interest ◽

One Year

IntroductionThe relationships between Eating Disorders (EDs) and sexuality are complex, and of interest for researchers and clinicians.ObjectiveTo identify psychopathological and clinical factors associated with restoration of regular menses and sexual function in EDs patients.AimsTo evaluate the role of sexuality as a moderator of the recovery process after an individual Cognitive Behavioural Therapy (CBT).Methods39 Anorexia Nervosa (AN) and 40 Bulimia Nervosa (BN) female patients were evaluated by means of a face-to-face interview, self-reported questionnaires, including Eating Disorder Examination Questionnaire and Female Sexual Function Index, and blood sample for hormonal levels and biomarkers. The assessments were repeated at baseline, at one year follow up, and at three years follow up.ResultsAfter CBT, both AN and BN patients showed a significant improvement of sexual functioning, which was associated with a reduction of core psychopathology. AN patients who recovered regular menses demonstrated a better improvement across time of psychopathological and clinical features, and were more likely to maintain these improvements at follow up. Recovery of regular menses and improvement of sexuality at the end of CBT were associated with a higher probability to have a full recovery at three years follow up.ConclusionsThese results challenge a concept of recovery in EDs exclusively based on weight restoration or behavioral changes. An assessment including sexual functioning and core psychopathology might identify the residual pathological conditions, and it is able to provide information regarding the long term recovery process.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Association between patient's personality traits and outcome of hospital treatment of opioid addiction

European Psychiatry ◽

10.1016/j.eurpsy.2016.01.1006 ◽

2016 ◽

Vol 33 (S1) ◽

pp. S296-S296 ◽

Cited By ~ 1

Author(s):

M. Delic ◽

K. Kajdiž ◽

P. Pregelj

Keyword(s):

Risk Factors ◽

Treatment Outcome ◽

Personality Traits ◽

Illicit Drugs ◽

Hospital Treatment ◽

Duration Of Treatment ◽

Research Interview ◽

Competing Interest ◽

One Year

IntroductionDespite different treatment approaches many drug addicted patients continue to use drugs during and after treatment.ObjectivesPersonality traits are considered risk factors for drug use, and, in turn, the psychoactive substances impact individuals’ traits.AimsTo describe the sample of 186 opioid addicted patients entered hospital treatment and assessing the differences in personality traits between abstinent and non-abstinent after one year.MethodsA cohort of 186 patients consecutively admitted to the detoxification unit was investigated. The research interview, the Big Five Inventory (BFI), the Treatment Outcomes Profile (TOP) were administered during the first week of admission to the detoxification unit. Urine test was administered on the day of admission and at each follow-up point in combination with the TOP (after three, six and twelve months). Illicit drugs abstinence during one year after intake was selected as a treatment outcome measure.ResultsTwelve months after admission 82 (44.9%) patients abstained completely. Agreeable patients remain in treatment longer (r = 0.20, P = 0.07). Extraversion and openness are negatively correlated with abstinence after six and twelve months (r = –0.15, P = 0.041; r = –0.15, P = 0.044). Neuroticism is in negative correlation with duration of treatment (r = –0.20, P = 0.006). Patients who are less open to new experiences are more likely to abstain from drugs 6 months after admission (r = –0.17, P = 0.021).ConclusionPersonality measured with BFI correlates with treatment outcome poorly. At the same time personality could have an important role in responding to treatment, but personality traits could be at the same time protective as well as risk factors.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Beliefs about antidepressants among persons aged 70 years and older in treatment after a suicide attempt

International Psychogeriatrics ◽

10.1017/s1041610215000216 ◽

2015 ◽

Vol 27 (11) ◽

pp. 1795-1803 ◽

Cited By ~ 2

Author(s):

Eva Lesén ◽

Stefan Wiktorsson ◽

Anders Carlsten ◽

Margda Waern ◽

Tove Hedenrud

Keyword(s):

Suicide Attempt ◽

Suicide Risk ◽

Older Persons ◽

Medication Use ◽

Objective Measures ◽

Psychiatric Evaluation ◽

Prior History ◽

History Of ◽

One Year

ABSTRACTBackground:The use of antidepressants is associated with decreased suicide risk in late life, and these drugs are often prescribed after a suicide attempt. Yet little is known about attitudes to antidepressants in older persons with suicidal behavior. The aim of this study was to assess beliefs about antidepressant medicines in older persons in treatment one year after a suicide attempt.Methods:Forty-four individuals aged 70 years and older, who were treated in emergency wards at five hospitals in western Sweden in connection with a suicide attempt, were interviewed at index attempt and one year later. Beliefs about medicines questionnaire (BMQ) specific for antidepressants were analyzed one year after index attempt, in relation to sociodemographic variables, medication use, psychiatric evaluation, and personality traits.Results:The majority of participants perceived the necessity of their antidepressant medicine to outweigh their concerns. Lower perceived necessity of antidepressants was observed in those who were not on antidepressants at the time of the attempt as well as those with no prior history of suicide attempt before the index attempt. Individuals reporting hopelessness at follow-up had a higher perceived concern about using medication.Conclusions:Beliefs about antidepressants tended to be more positive than negative in older persons taking these drugs in the aftermath of a suicide attempt. Further studies are called for, and should include objective measures of medication adherence.

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Does Adolescents’ Depressive Symptoms Increase the Possibility of Addictive Internet Gaming?: 1-year Follow up Study in Korea

European Psychiatry ◽

10.1016/j.eurpsy.2017.01.2159 ◽

2017 ◽

Vol 41 (S1) ◽

pp. S204-S204 ◽

Cited By ~ 1

Author(s):

S.J. Jo ◽

H.W. Yim ◽

J. Hyunsuk ◽

K. Eunjin ◽

S. Hye-Jung ◽

...

Keyword(s):

Depressive Symptoms ◽

Self Control ◽

Child Depression ◽

Baseline Assessment ◽

Observation Study ◽

Internet Gaming ◽

Child Depression Inventory ◽

Competing Interest ◽

One Year

IntroductionAdolescents’ Internet gaming disorders might influence on their social and psychological developmental tasks and physical health negatively. Depression is the commonly co-existed conditions with addictive Internet gaming, but not much research has been reported whether depressive symptoms would precede the addictive Internet gaming in this population.ObjectivesThis prospective observation study was performed to make clear whether adolescents’ depressive symptoms precede their addictive Internet gaming.AimsAdolescents’ 1-year incidence of the addictive Internet gaming was calculated, and test their depressive symptoms increase the incidence.MethodsIn Korea, whole students of the 1st grade in three middle schools were participated in this study. Baseline assessment of 508 students was performed via standardized self-reported questionnaire on May–June, 2015. Internet game use-elicited symptom screen (IGUESS) was used to addictive Internet gaming conditions. IGUESS is the 9-itemed DSM-5 diagnostic criteria-based instrument to screen high risk of Internet gaming disorders. Depressive symptoms was measured by Child Depression Inventory (CDI) group. One year after the baseline assessment, follow-up assessment was performed. Four hundred and forty-eight students have been participated in the 1-year check up without addictive Internet gaming at baseline.ResultsIn total, 4.7% of subjects had depressive symptoms at baseline, and incidence of addictive Internet gaming was 9.2%. After adjusted by sex, Internet game use per week, and self-control status, depressive symptoms of baseline increased the 1-year incidence of addictive Internet gaming significantly (OR = 3.5, P = 0.034).ConclusionsDepressive adolescents have higher possibility they could experience the addictive Internet gaming.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Assessing the Efficacy of a Cultural and Artistic Intervention for Indigenous Women Who Have Experienced Intimate Partner Violence

Violence Against Women ◽

10.1177/10778012211058220 ◽

2021 ◽

pp. 107780122110582

Author(s):

Crystal J. Giesbrecht ◽

Laleh Jamshidi ◽

Carrie LaVallie ◽

JoLee Sasakamoose ◽

R. Nicholas Carleton

Keyword(s):

Intimate Partner Violence ◽

Partner Violence ◽

Positive Impact ◽

Well Being ◽

Intimate Partner ◽

Indigenous Women ◽

Self Report ◽

Post Intervention ◽

One Year

nato’ we ho win is a trauma-and-violence-informed artistic and cultural intervention for Indigenous women who have experienced intimate partner violence. The results of this study provide evidence that engagement in nato’ we ho win had a positive impact on participants’ well-being. Participants completed self-report questionnaires at intake, post-intervention, and at one-year follow-up. Multilevel modeling analyses assessed for within-participant changes over time. There was a statistically significant increase in participants’ self-reported sense of resilience ( p < 0.001), personal agency, connectedness, and post-traumatic growth ( ps < 0.05). There were statistically significant decreases in participants’ self-reported anxiety and depression ( p s < 0.01) from intake to one-year follow-up.

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Mixed-effects models: Family burden and functionality in patients with bipolar disorder

European Psychiatry ◽

10.1016/j.eurpsy.2016.01.1147 ◽

2016 ◽

Vol 33 (S1) ◽

pp. S331-S331 ◽

Cited By ~ 1

Author(s):

C. Bermúdez-Ampudia ◽

A. García-Alocén ◽

M. Martínez-Cengotitabengoa ◽

S. Alberich ◽

I. González-Ortega ◽

...

Keyword(s):

Bipolar Disorder ◽

Control Group ◽

Subjective Burden ◽

The Family ◽

Modifiable Factor ◽

Objective Burden ◽

Competing Interest ◽

One Year ◽

Experimental Group

IntroductionThe bipolar disorder (BD) has an important effect over the lives of patients and families. The attitude of the family is a modifiable factor through specific interventions and it has been related with BD prognosis.ObjectivesStudy a sample of families and patients with BD.AimsCompare between two groups its course of burden of caring for family members with BD. Also, we will see the course of the functionality in patients.MethodsSample of 148 individuals who caring a familiar with BD. Seventy-six of these followed psychoeducation session are going to be experimental group (EG), and the others 72 did not followed any session are going to be control group (CG). There is a follow-up at 6 months and one year. To see the course of the burden and the functionality it will be used mixed models.ResultsAt baseline, there were not significant differences between CG and EG in objective and subjective burden and functionality. But over time there were significant results in the three cases. For objective burden (b = −0.016; P = 0.0001) EG presented a drop (b = −0.014; P = 0.0062), while CG did not show changes (b = 0.002; P = 0.4691). For subjective burden (b = −0.014; P = 0.0058) without significant results for CG (b = −0.352; P = 0.3203) and a significant decrease in EG (b = −0.017; P = 0.003). For the functionality (b = 1.474; P = 0.000) there was a significant increase in EG (b = 1.349; P = 0.000) but not for CG (b = −0.125; P = 0.3828).ConclusionsTwo groups did not differ at baseline however after the psychoeducation sessions appear clear differences, decreasing the burden for EG group and the functionality also improved for EG.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Epidemiological, clinical and evolutionary aspects of hypotrophic newborns at term at the Mother and Child University Hospital of N'Djamena

World Journal of Advanced Research and Reviews ◽

10.30574/wjarr.2022.13.1.0764 ◽

2022 ◽

Vol 13 (1) ◽

pp. 180-188

Author(s):

Silé Souam Nguélé ◽

Adrienne Ngaringuem ◽

Kounnezouné Patalet ◽

Kanezouné Gongnet ◽

Djaury Dadji-a ◽

...

Keyword(s):

Perinatal Asphyxia ◽

Public Health Problem ◽

Neonatal Morbidity ◽

Home Delivery ◽

Morbidity And Mortality ◽

University Hospital ◽

High Morbidity ◽

Urogenital Infections ◽

Mother And Child

Introduction: Hypotrophy is a public health problem in developing countries. Its etiology is multifactorial and it may be associated with high morbidity and mortality. The objective of this study was to describe the epidemiological, clinical and evolutionary profile of hypotrophic newborns at term. Methodology: this was a prospective, descriptive and analytical study conducted in the neonatology department of the MCUH of N'Djamena from 01/06/2018 to 31/05/2019. It involved 109 hypotrophic newborns at term hospitalized. Results: The frequency of hypotrophy was 7.8%, the risk factors were: housewife status (81.7%), low level of education (67%), poor pregnancy follow-up (59.7%), malaria (40.4%), urogenital infections (22%) and anemia (22%) during pregnancy. Hypotrophy was harmonious in 58.7% of cases, the sex ratio was 1.14 and visible congenital malformations were observed in 12.7% of cases. The main reasons for hospitalization were neonatal infections (64.2%), perinatal asphyxia (14.7%) and hypothermia (11.9%). Lethality was 16.5% and associated with multiparity, poor pregnancy follow-up, vaginal delivery, home delivery, pathological Apgar score, notion of resuscitation, existence of malformation, respiratory distress and perinatal asphyxia. Conclusion: Better monitoring of pregnancy, use of family planning by couples, delivery in an institutionalized setting, and reinforcement of the technical platform of the neonatology department will reduce neonatal morbidity and mortality related to hypotrophy.

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Mental Pain Expression in Psychopathology and its Assessment as a Therapeutic Outcome Measurement

European Psychiatry ◽

10.1016/j.eurpsy.2016.01.1748 ◽

2016 ◽

Vol 33 (S1) ◽

pp. S478-S478 ◽

Cited By ~ 1

Author(s):

G. Becker ◽

E. Steiner ◽

U. Nitzan ◽

A. Grossman-Giron

Keyword(s):

Outcome Measurement ◽

Therapeutic Process ◽

Pain Scale ◽

Annihilation Anxiety ◽

Mental Pain ◽

Pain Expression ◽

Important Symptom ◽

Competing Interest ◽

One Year

IntroductionEvery theory that explains psychopathology refers to different aspects of mental pain whether it regards annihilation anxiety, fragmentation of the self or feelings of intolerable anguish. The concept of mental pain has proved to be an important symptom in mood disorders in general and suicide in particular (Orbach et al., 2004; Levi et al., 2010; Levinger et al., 2015). Combining the understanding that mental pain is as a part of all forms of psychopathology with the growing interest in assessing therapeutic processes via outcome measures has led to the assumption that the tolerance and severity of mental pain could become powerful outcome measurement. The aim of this study is to assess the Mental Pain Scale (OMMP) and Tolerance to Mental Pain Scale (TMPS) as outcome measurement and to learn about their capabilities to distinguish between different psychopathologies.ObjectiveThe first objective would be to examine patterns of mental pain subscales in different psychopathologies. The second objective is to assess the OMMP and TMPS as outcome measurements.MethodTwo hundred and thirty outpatients were administered a clinical questionnaire battery composed of eight questionnaires. The patients were to fill these questionnaires every 3 months for one year or until the end of their therapy.ResultsWe will present preliminary findings regarding the expressions of mental pain in different kinds of psychopathology and results of 3 months follow-up.ConclusionTolerance and severity of mental pain are a vital to the assessment of psychopathology and should be used as outcome measurement of therapeutic process.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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