Predictors of cognitive impairment assessed by Mini Mental State Examination in community-dwelling older adults: relevance of the step test

2018 ◽  
Vol 108 ◽  
pp. 69-76 ◽  
Author(s):  
Antonio Muscari ◽  
Ilaria Spiller ◽  
Giampaolo Bianchi ◽  
Elisa Fabbri ◽  
Paola Forti ◽  
...  
Author(s):  
Ngeemasara Thapa ◽  
Boram Kim ◽  
Ja-Gyeong Yang ◽  
Hye-Jin Park ◽  
Minwoo Jang ◽  
...  

Our study examined the association between chronotype, daily physical activity, and the estimated risk of dementia in 170 community-dwelling older adults. Chronotype was assessed with the Horne–Östberg Morningness–Eveningness Questionnaire (MEQ). Daily physical activity (of over 3 METs) was measured with a tri-axial accelerometer. The Korean version of the Mini-Mental State Examination (K-MMSE) was used to measure the estimated risk of dementia. The evening chronotype, low daily physical activity, and dementia were positively associated with each other. The participants with low physical activity alongside evening preference had 3.05 to 3.67 times higher estimated risk of developing dementia, and participants with low physical activity and morning preference had 1.95 to 2.26 times higher estimated risk than those with high physical activity and morning preference. Our study design does not infer causation. Nevertheless, our findings suggest that chronotype and daily physical activity are predictors of the risk of having dementia in older adults aged 70 years and above.


2012 ◽  
Vol 24 (11) ◽  
pp. 1725-1731 ◽  
Author(s):  
Cláudia Rodrigues Monteiro Macuco ◽  
Samila Satler Tavares Batistoni ◽  
Andrea Lopes ◽  
Meire Cachioni ◽  
Deusivânia Vieira da Silva Falcão ◽  
...  

ABSTRACTBackground: Frailty in older adults is a multifactorial syndrome defined by low metabolic reserve, less resistance to stressors, and difficulty in maintaining organic homeostasis due to cumulative decline of multiple physiological systems. The relationship between frailty and cognition remains unclear and studies about Mini-Mental State Examination (MMSE) performance and frailty are scarce. The objective was to examine the association between frailty and cognitive functioning as assessed by the MMSE and its subdomains.Methods: A cross-sectional population-based study (FIBRA) was carried out in Ermelino Matarazzo, a poor subdistrict of the city of São Paulo, Brazil. Participants were 384 community dwelling older adults, 65 years and older who completed the MMSE and a protocol to assess frailty criteria as described in the Cardiovascular Health Study (CHS).Results: Frail older adults had significantly worse performance on the MMSE (p < 0.001 for total score). Linear regression analyses showed that the MMSE total score was influenced by age (p < 0.001), education (p < 0.001), family income (p < 0.001), and frailty status (p < 0.036). Being frail was associated more significantly with worse scores in Time Orientation (p < 0.004) and Immediate Memory (p < 0.001).Conclusions: Our data suggest that being frail is associated with worse cognitive performance, as assessed by the MMSE. It is recommended that the assessment of frail older adults should include the investigation of their cognitive status.


2000 ◽  
Vol 30 (3) ◽  
pp. 605-618 ◽  
Author(s):  
RICHARD N. JONES ◽  
JOSEPH J. GALLO

Background. Little work has been published on the internal structure of the Mini-Mental State Examination (MMSE), one of the most widely used instruments for grading cognitive status in clinical settings and field research.Methods. MMSE responses from a sample of older adults (50–98 years) in five US sites (N = 8556) were analysed.Results. A five-factor solution was found to be most appropriate. The first factor (concentration) had large loadings with serial sevens and spell world backwards items. The second factor (language and praxis) had large loadings with naming, follow command and praxis items. The third factor (orientation) had loadings with orientation to time and place items. The fourth factor (memory) had large loadings with delayed recall items and the fifth (attention) had large loadings with immediate registration items.Conclusions. We found that the MMSE is essentially unidimensional; nevertheless, evidence was revealed suggesting that the MMSE is a multidimensional assessment instrument. Dimensions revealed in this sample correspond directly to MMSE sections articulated by the developers of the instrument. These findings have not been reported in previous factor analyses of the MMSE. The findings support the construct validity of the MMSE as a measure of cognitive mental state among community dwelling older adults.


Author(s):  
Carol Hudon ◽  
Olivier Potvin ◽  
Marie-Christine Turcotte ◽  
Catherine D’Anjou ◽  
Micheline Dubé ◽  
...  

ABSTRACTThis study was aimed at providing normative data for the Mini-Mental State Examination (MMSE). The norms were built from a sample (n = 2409) of community-dwelling French speaking residents from Québec aged 65 and older. The analyses indicated that socio-demographic variables such as education level, age, and gender of individuals influenced significantly the scores of older adults on the MMSE. More precisely, MMSE scores increased with education level and decreased with age. Moreover, women had significantly higher scores than men. On this basis, distinct tables of normative data were produced for women and men. In each table, the MMSE scores corresponding to percentiles 5, 10, 15 and 50 were identified according to four age categories and three education levels. Overall, the use of the present normative data by clinicians will improve their accuracy in detecting cognitive impairment in older adults from Québec.


2018 ◽  
Vol 31 (5) ◽  
pp. 693-701 ◽  
Author(s):  
Ryan Van Patten ◽  
Karysa Britton ◽  
Geoffrey Tremont

ABSTRACTObjectives:To show enhanced psychometric properties and clinical utility of the modified Mini-Mental State Examination (3MS) compared to the Mini-Mental State Examination (MMSE) in mild cognitive impairment (MCI).Design:Psychometric and clinical comparison of the 3MS and MMSE.Setting:Neuropsychological clinic in the northeastern USA.Participants:Older adults referred for cognitive concerns, 87 of whom were cognitively intact (CI) and 206 of whom were diagnosed with MCI.Measurements:The MMSE, the 3MS, and comprehensive neuropsychological evaluations.Results:Both instruments were significant predictors of diagnostic outcome (CI or MCI), with comparable odds ratios, but the 3MS explained more variance and showed improved classification accuracies relative to the MMSE. The 3MS also demonstrated greater receiver operating characteristic area under the curve values (0.85, SE = 0.02) compared to the MMSE (0.74, SE = 0.03). Scoring lower than 95/100 on the 3MS suggested MCI, while scoring lower than 28/30 on the MMSE suggested MCI. Additionally, compared to the MMSE, the 3MS shared more variance with neuropsychological composite scores in Language and Memory domains but not in Attention, Visuospatial, and Executive domains. Finally, 65.5% MCI patients were classified as impaired (scoring ≤1 SD below the mean) using 3MS normative data, compared to only 11.7% of patients who were classified as impaired using MMSE normative data.Conclusions:Broadly speaking, our data strongly favor the widespread substitution of the MMSE with the 3MS in older adults with concerns for cognitive decline.


2021 ◽  
Vol 79 (5) ◽  
pp. 376-383
Author(s):  
Gabriela Cabett Cipolli ◽  
Ivan Aprahamian ◽  
Flávia Silva Arbex Borim ◽  
Deusivania Vieira Silva Falcão ◽  
Meire Cachioni ◽  
...  

ABSTRACT Background: The link between sarcopenia and cognitive impairment has not yet been thoroughly evaluated, especially among older adults. Objective: To evaluate the relationship between probable sarcopenia and cognitive impairment among community-dwelling older adults in two Brazilian cities. Methods: Probable sarcopenia was assessed using the EWGSOP2 (2018) criteria. Thus, participants were classified as probably having sarcopenia if they had SARC-F (Strength, Assistance in walking, Rise from a chair, Climb stairs and Falls) ≥4 points and low grip strength. Cognitive function was evaluated through the Mini-Mental State Examination (MMSE), verbal fluency (VF) and clock drawing test (CDT). Results: In a sample of 529 older adults (mean age 80.8±4.9 years; mean education 4.2±3.67 years; 70.1% women), 27.3% of the participants had SARC-F≥4, 38.3% had low grip strength and 13.6% were classified as probable sarcopenia cases. After adjusting for possible confounders (age, sex, education, depression, diabetes, hypertension, leisure-time physical activity and obesity), probable sarcopenia was found to be associated with impairment in the MMSE (OR 2.52; 95%CI 1.42‒4.47; p=0.002) and in VF (OR 2.17; 95%CI 1.17‒4.01; p=0.014). Low grip strength was found to be associated with impairment in the MMSE (OR 1.83; 95%CI 1.18‒2.82; p=0.006) and in the CDT (OR 1.79; 95%CI 1.18‒2.73; p=0.006). SARC-F scores were found to be associated with impairment in the MMSE (OR 1.90; 95%CI 1.18‒3.06; p=0.008). Conclusion: The results suggested that probable sarcopenia and its components present a significant association with cognitive deficits among community-dwelling older adults. Future longitudinal studies will further explore the causal relationship.


2020 ◽  
Vol 7 (1) ◽  
pp. 45
Author(s):  
RakeshKumar Tripathi ◽  
NishaMani Pandey ◽  
ShailendraMohan Tripathi ◽  
Bhupendra Singh ◽  
SarvadaC Tiwari

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