Manuka honey in combination with 5-Fluorouracil decreases physical parameters of colonspheres enriched with cancer stem-like cells and reduces their resistance to apoptosis

2022 ◽  
Vol 374 ◽  
pp. 131753
Author(s):  
Danila Cianciosi ◽  
Tamara Y. Forbes-Hernández ◽  
Lucia Regolo ◽  
José M. Alvarez-Suarez ◽  
Denise Quinzi ◽  
...  
1965 ◽  
Vol 5 ◽  
pp. 120-130
Author(s):  
T. S. Galkina

It is necessary to have quantitative estimates of the intensity of lines (both absorption and emission) to obtain the physical parameters of the atmosphere of components.Some years ago at the Crimean observatory we began the spectroscopic investigation of close binary systems of the early spectral type with components WR, Of, O, B to try and obtain more quantitative information from the study of the spectra of the components.


Author(s):  
J.T. Fourie

Contamination in electron microscopes can be a serious problem in STEM or in situations where a number of high resolution micrographs are required of the same area in TEM. In modern instruments the environment around the specimen can be made free of the hydrocarbon molecules, which are responsible for contamination, by means of either ultra-high vacuum or cryo-pumping techniques. However, these techniques are not effective against hydrocarbon molecules adsorbed on the specimen surface before or during its introduction into the microscope. The present paper is concerned with a theory of how certain physical parameters can influence the surface diffusion of these adsorbed molecules into the electron beam where they are deposited in the form of long chain carbon compounds by interaction with the primary electrons.


Author(s):  
Linda Sicko-Goad

Although the use of electron microscopy and its varied methodologies is not usually associated with ecological studies, the types of species specific information that can be generated by these techniques are often quite useful in predicting long-term ecosystem effects. The utility of these techniques is especially apparent when one considers both the size range of particles found in the aquatic environment and the complexity of the phytoplankton assemblages.The size range and character of organisms found in the aquatic environment are dependent upon a variety of physical parameters that include sampling depth, location, and time of year. In the winter months, all the Laurentian Great Lakes are uniformly mixed and homothermous in the range of 1.1 to 1.7°C. During this time phytoplankton productivity is quite low.


Author(s):  
P.-F. Staub ◽  
C. Bonnelle ◽  
F. Vergand ◽  
P. Jonnard

Characterizing dimensionally and chemically nanometric structures such as surface segregation or interface phases can be performed efficiently using electron probe (EP) techniques at very low excitation conditions, i.e. using small incident energies (0.5<E0<5 keV) and low incident overvoltages (1<U0<1.7). In such extreme conditions, classical analytical EP models are generally pushed to their validity limits in terms of accuracy and physical consistency, and Monte-Carlo simulations are not convenient solutions as routine tools, because of their cost in computing time. In this context, we have developed an intermediate procedure, called IntriX, in which the ionization depth distributions Φ(ρz) are numerically reconstructed by integration of basic macroscopic physical parameters describing the electron beam/matter interaction, all of them being available under pre-established analytical forms. IntriX’s procedure consists in dividing the ionization depth distribution into three separate contributions:


Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
C Bäcker ◽  
K Wende ◽  
U Meyer ◽  
U Lindequist
Keyword(s):  

2006 ◽  
Vol 2 (1) ◽  
pp. 73-94 ◽  
Author(s):  
Péter Mészáros ◽  
David B. Funk

The Unified Grain Moisture Algorithm is capable of improved accuracy and allows the combination of many grain types into a single “unified calibration”. The purposes of this research were to establish processes for determining unifying parameters from the chemical and physical properties of grains. The data used in this research were obtained as part of the United States Department of Agriculture-Grain Inspection, Packers and Stockyards Administration's Annual Moisture Calibration Study. More than 5,000 grain samples were tested with a Hewlett-Packard 4291A Material/Impedance Analyzer. Temperature tests were done with a Very High Frequency prototype system at Corvinus University of Budapest. Typical chemical and physical parameters for each of the major grain types were obtained from the literature. Data were analyzed by multivariate chemometric methods. One of the most important unifying parameters (Slope) and the temperature correction coefficient were successfully modeled. The Offset and Translation unifying parameters were not modeled successfully, but these parameters can be estimated relatively easily through limited grain tests.


Author(s):  
J. Buggaramulu ◽  
M. Venkatakrishna ◽  
Y. Harikrishna

The objective of this paper is to analyze an unsteady MHD free convective heat and mass transfer boundary flow past a semi-infinite vertical porous plate immersed in a porous medium with radiation and chemical reaction. The governing equations of the flow field are solved numerical a two term perturbation method. The effects of the various parameters on the velocity, temperature and concentration profiles are presented graphically and values of skin-frication coefficient, Nusselt number and Sherwood number for various values of physical parameters are presented through tables.


2014 ◽  
Vol 13 (1) ◽  
Author(s):  
Jan Piekarczyk

AbstractWith increasing intensity of agricultural crop production increases the need to obtain information about environmental conditions in which this production takes place. Remote sensing methods, including satellite images, airborne photographs and ground-based spectral measurements can greatly simplify the monitoring of crop development and decision-making to optimize inputs on agricultural production and reduce its harmful effects on the environment. One of the earliest uses of remote sensing in agriculture is crop identification and their acreage estimation. Satellite data acquired for this purpose are necessary to ensure food security and the proper functioning of agricultural markets at national and global scales. Due to strong relationship between plant bio-physical parameters and the amount of electromagnetic radiation reflected (in certain ranges of the spectrum) from plants and then registered by sensors it is possible to predict crop yields. Other applications of remote sensing are intensively developed in the framework of so-called precision agriculture, in small spatial scales including individual fields. Data from ground-based measurements as well as from airborne or satellite images are used to develop yield and soil maps which can be used to determine the doses of irrigation and fertilization and to take decisions on the use of pesticides.


Author(s):  
Laxman Devkota ◽  
Bhupendra Poudel ◽  
Junu Silwal

The objective of the present study is to develop chewable tablets containing different pharmaceutical compositions with simple manufacturing procedures using different excipients. Mannitols, L-HPC 11, Aspartame, Crospovidone, Crospovidone, Aerosil, and Magnesium Stearate are used as excipients for effective formulation of anti-asthmatic drug Montelukast. Montelukast is a selective, orally acting leukotriene receptor antagonist that is used for the treatment of asthma and seasonal allergic rhinitis. Montelukast chewable tablets were prepared by Direct Compression methods using suitable excipients. The chewable tablets were better presented using artificial sweetener Aspartame as flavouring agent. A total of forteen formulations were prepared and the granules were evaluated for pre-compression parameters. The formulated tablets were evaluated for post-compression parameters .The results showed that all the physical parameters were within the acceptable limits. The in vitro release study of all the formulations showed good release. The study concludes that aforementioned excipients can be used to design chewable montelukast sodium tablets.


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