Numerical investigations were conducted on flow and heat transfer in an outward convex corrugated tube with various structural twisted tape inserts. The study investigated the influence of twisted ratio on thermodynamic regulation and mechanism in the corrugated tube. The results indicate that Nusselt number in the corrugated tube (Nuc) exceeds those in the corrugated tube and smooth tube by 120-136% and 171-317%, respectively. Meanwhile, the friction factor increases by 148-153% and 476-514%, respectively. The best overall thermal performance (h = 1.97) is obtained with a high twist ratio (y/w = 5). However, the highest thermal performance (Nuc/Nus = 4.78) is obtained with the lowest twist ratio (y/w = 1.25).