Prognostic value of the infarct- and non-infarct like patterns and cardiovascular magnetic resonance parameters on long-term outcome of patients after acute myocarditis

2016 ◽  
Vol 212 ◽  
pp. 63-69 ◽  
Author(s):  
Houzefa Chopra ◽  
Dimitri Arangalage ◽  
Claire Bouleti ◽  
Samuel Zarka ◽  
Florence Fayard ◽  
...  
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Prognostic Value ◽  
Acute Myocarditis ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Resonance Parameters ◽  
Magnetic Resonance Parameters

Long-term outcome of myocardial scarring and deformation with cardiovascular magnetic resonance in out of hospital cardiac arrest survivors

2020 ◽  
Author(s):  
Anna Baritussio ◽  
Giovanni Biglino ◽  
Alessandra Scatteia ◽  
Estefania De Garate ◽  
Amardeep Ghosh Dastidar ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Adverse Events ◽  
Myocardial Deformation ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Myocardial Scarring ◽  
Hospital Cardiac Arrest

Abstract Aims Cardiovascular magnetic resonance (CMR) is increasingly recognized as a diagnostic and prognostic tool in out of hospital cardiac arrest (OHCA) survivors. After assessing CMR findings early after ventricular fibrillation (VF) OHCA, we sought to explore the long-term outcome of myocardial scarring and deformation. Methods and results We included 121 consecutive VF OHCA survivors (82% male, median 62 years) undergoing CMR within 2 weeks from cardiac arrest. Late gadolinium-enhancement (LGE) was quantified using the full width at half maximum method and tissue tracking analysis software was used to assess myocardial deformation. LGE was found in 71% of patients (median LGE mass 6.2% of the left ventricle, LV), mainly with an ischaemic pattern. Myocardial deformation was overall impaired and showed a significant correlation with LGE presence and extent (P < 0.001). A composite end-point of all-cause mortality and appropriate ICD discharge/anti-tachycardia pacing was met in 24% of patients. Patients meeting the end-point had significantly greater LGE extent (8.6% of LV myocardium vs. 4.1%, P = 0.02), while there was no difference with regards to myocardial deformation. Survival rate was significantly lower in patients with LGE (P = 0.05) and LGE mass >4.4% of the LV identified a group of patients at higher risk of adverse events (P = 0.005). Conclusions We found a high prevalence of LGE, early after OHCA, and an overall impaired myocardial deformation. On long-term follow-up both LGE presence and extent showed a significant association with recurrent adverse events, while LV ejection fraction and myocardial deformation did not identify patients with an unfavourable outcome.

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