Protective effect of a purified polyphenolic extract from Ecklonia cava against noise-induced hearing loss: Prevention of temporary threshold shift

2016 ◽  
Vol 87 ◽  
pp. 178-184 ◽  
Author(s):  
Mun Young Chang ◽  
Song Yee Han ◽  
Hyeon-Cheol Shin ◽  
Jang Yul Byun ◽  
Yoon Chan Rah ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Protective Effect ◽  
Threshold Shift ◽  
Ecklonia Cava ◽  
Temporary Threshold Shift ◽  
Noise Induced Hearing Loss ◽  
Loss Prevention ◽  
Polyphenolic Extract

scholarly journals Effect of Phlorofucofuroeckol A and Dieckol Extracted from Ecklonia cava on Noise-induced Hearing Loss in a Mouse Model

Marine Drugs ◽  
2021 ◽  
Vol 19 (8) ◽  
pp. 443
Author(s):  
Hyunjun Woo ◽  
Min-Kyung Kim ◽  
Sohyeon Park ◽  
Seung-Hee Han ◽  
Hyeon-Cheol Shin ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hair Cell ◽  
Noise Exposure ◽  
Radical Scavenging ◽  
Threshold Shift ◽  
Ecklonia Cava ◽  
Control Group ◽  
Noise Induced Hearing Loss ◽  
Antioxidant Agents ◽  
Brainstem Response

One of the well-known causes of hearing loss is noise. Approximately 31.1% of Americans between the ages of 20 and 69 years (61.1 million people) have high-frequency hearing loss associated with noise exposure. In addition, recurrent noise exposure can accelerate age-related hearing loss. Phlorofucofuroeckol A (PFF-A) and dieckol, polyphenols extracted from the brown alga Ecklonia cava, are potent antioxidant agents. In this study, we investigated the effect of PFF-A and dieckol on the consequences of noise exposure in mice. In 1,1-diphenyl-2-picrylhydrazyl assay, dieckol and PFF-A both showed significant radical-scavenging activity. The mice were exposed to 115 dB SPL of noise one single time for 2 h. Auditory brainstem response(ABR) threshold shifts 4 h after 4 kHz noise exposure in mice that received dieckol were significantly lower than those in the saline with noise group. The high-PFF-A group showed a lower threshold shift at click and 16 kHz 1 day after noise exposure than the control group. The high-PFF-A group also showed higher hair cell survival than in the control at 3 days after exposure in the apical turn. These results suggest that noise-induced hair cell damage in cochlear and the ABR threshold shift can be alleviated by dieckol and PFF-A in the mouse. Derivatives of these compounds may be applied to individuals who are inevitably exposed to noise, contributing to the prevention of noise-induced hearing loss with a low probability of adverse effects.

Noise

2020 ◽  
pp. 1671-1673
Author(s):  
David Koh ◽  
Tar-Ching Aw
Keyword(s):  
Cardiovascular Disease ◽  
Hearing Loss ◽  
Sleep Disturbance ◽  
Cognitive Performance ◽  
Noise Exposure ◽  
Threshold Shift ◽  
Temporary Threshold Shift ◽  
Noise Induced Hearing Loss ◽  
Occupational Setting ◽  
Human Ear

Noise can affect hearing in the occupational setting but can have other effects where exposures are non-occupational. For clinical purposes, noise is measured in decibels weighted according to the sensitivity of the human ear (dB(A)). Regardless of source, the effects of overexposure to noise are similar. Initially there is a temporary threshold shift, where reversibility of hearing loss is possible with removal away from further noise. Noise-induced hearing loss occurs following prolonged or intense exposure, with poor prospects for improvement of hearing. The classical audiogram for noise-induced hearing loss shows a 4 kHz dip. Non-auditory effects of prolonged noise exposure include annoyance, sleep disturbance, hypertension, and cardiovascular disease, stress, and impaired cognitive performance. Prevention of noise-induced hearing loss is by reducing exposure to noise at source minimizing exposure time, using hearing protection, and participating in surveillance.

Noise

2010 ◽  
pp. 1432-1434
Author(s):  
Syed M. Ahmed ◽  
Tar-Ching Aw
Keyword(s):  
Hearing Loss ◽  
United Kingdom ◽  
Impulse Noise ◽  
Threshold Shift ◽  
Temporary Threshold Shift ◽  
Noise Induced Hearing Loss ◽  
The United Kingdom ◽  
Human Ear

For clinical purposes, noise is measured in decibels weighted according to the sensitivity of the human ear (dB(A)). Regardless of source, the effects of overexposure to noise are similar. Initially there is a temporary threshold shift, where reversibility of hearing loss is possible with removal away from further noise. Permanent threshold shift occurs following prolonged and/or intense exposure, with poor prospects for improvement of hearing. The classical audiogram for noise-induced hearing loss shows a 4 kHz dip. Prevention is by reducing exposure to noise at source, and in the United Kingdom a limit for exposure has been set at 87 dB(A) averaged over an 8-h day or 140 dB(A) for any instantaneous impulse noise....

The protective effect of metformin against the noise-induced hearing loss

2018 ◽  
Vol 275 (12) ◽  
pp. 2957-2966 ◽  
Author(s):  
Gülin Gökçen Kesici ◽  
Fatma Ceyda Akın Öcal ◽  
Seren Gülşen Gürgen ◽  
Şaban Remzi Erdem ◽  
Ersin Öğüş ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Protective Effect ◽  
Noise Induced Hearing Loss

Protective Effect of Isoflurane on Noise-induced Hearing Loss in Mice

2005 ◽  
Vol 49 (4) ◽  
pp. 523
Author(s):  
Seung Woo Ku ◽  
Jin Woo Shin ◽  
Ji Yeon Lee ◽  
Joung Uk Kim ◽  
Su Keoung Lee ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Protective Effect ◽  
Noise Induced Hearing Loss

Temporary Threshold Shift from a Toy Cap Gun

1974 ◽  
Vol 39 (2) ◽  
pp. 163-168 ◽  
Author(s):  
Lynne Marshall ◽  
John F. Brandt
Keyword(s):  
Hearing Loss ◽  
Sound Pressure Level ◽  
Sound Pressure ◽  
Noise Exposure ◽  
Pressure Level ◽  
Threshold Shift ◽  
Temporary Threshold Shift ◽  
Fixed Frequency ◽  
Before And After ◽  
The Subject

Temporary threshold shift resulting from exposure to one and five toy cap gun pistol shots was investigated using 11 normal-hearing adult subjects and one subject with a noise-induced hearing loss. The subjects fired the cap gun at arm’s length, and absolute thresholds at 4000 Hz were obtained before and after noise exposure by a fixed-frequency Bekesy technique. After exposure to one gunshot, five subjects showed a small TTS, five demonstrated no TTS, and two (including the subject with the hearing loss) exhibited negative TTS. No TTS occurred in any of the subjects after exposure to five shots. It was postulated that the small amount of TTS was due to the unexpectedly low sound pressure level produced by the cap gun and to the contraction of the middle ear muscles in some subjects prior to firing.

scholarly journals Protective effect of unilateral and bilateral ear plugs on noise-induced hearing loss: Functional and morphological evaluation in animal model

2014 ◽  
Vol 16 (70) ◽  
pp. 149 ◽  
Author(s):  
Shi-Nae Park ◽  
Dong-Kee Kim ◽  
Yooyeon Park ◽  
Sang-A Back ◽  
HongLim Kim ◽  
...  
Keyword(s):  
Animal Model ◽  
Hearing Loss ◽  
Protective Effect ◽  
Noise Induced Hearing Loss ◽  
Morphological Evaluation

Protective Effect of Isoflurane Anesthesia on Noise-Induced Hearing Loss in Mice

2005 ◽  
Vol 115 (11) ◽  
pp. 1996-1999 ◽  
Author(s):  
Joung Uk Kim ◽  
Hyun Jung Lee ◽  
Hun Hee Kang ◽  
Jin Woo Shin ◽  
Seung Woo Ku ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Protective Effect ◽  
Noise Induced Hearing Loss ◽  
Isoflurane Anesthesia
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