Mechanisms and review of clinical evidence for variations in relative biological effectiveness in proton therapy

2021 ◽  
Author(s):  
Harald Paganetti
Keyword(s):  
Proton Therapy ◽  
Clinical Evidence ◽  
Relative Biological Effectiveness ◽  
Biological Effectiveness

scholarly journals Clinically relevant nanodosimetric simulation of DNA damage complexity from photons and protons

RSC Advances ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 6845-6858 ◽  
Author(s):  
N. T. Henthorn ◽  
J. W. Warmenhoven ◽  
M. Sotiropoulos ◽  
A. H. Aitkenhead ◽  
E. A. K. Smith ◽  
...  
Keyword(s):  
Dna Damage ◽  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Proton Therapy ◽  
Relative Biological Effectiveness ◽  
Biological Effectiveness ◽  
Mechanistic Understanding

Relative Biological Effectiveness (RBE) is a controversial and important topic in proton therapy. This work uses Monte Carlo simulations of DNA damage for protons and photons to probe this phenomenon, providing a plausible mechanistic understanding.

scholarly journals Variation in relative biological effectiveness for cognitive structures in proton therapy of pediatric brain tumors

2020 ◽  
pp. 1-8
Author(s):  
Ole Marius Otterlei ◽  
Daniel J. Indelicato ◽  
Laura Toussaint ◽  
Kristian S. Ytre-Hauge ◽  
Sara Pilskog ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Proton Therapy ◽  
Relative Biological Effectiveness ◽  
Pediatric Brain Tumors ◽  
Cognitive Structures ◽  
Biological Effectiveness ◽  
Pediatric Brain

scholarly journals Relative biological effectiveness of therapeutic proton beams for HSG cells at Japanese proton therapy facilities

2014 ◽  
Vol 55 (4) ◽  
pp. 812-815 ◽  
Author(s):  
Mizuho Aoki-Nakano ◽  
Yoshiya Furusawa ◽  
Akiko Uzawa ◽  
Yoshitaka Matsumoto ◽  
Ryoichi Hirayama ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Relative Biological Effectiveness ◽  
Proton Beams ◽  
Biological Effectiveness
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