Ozone as eustress for enhancing secondary metabolites and bioactive properties in Salvia officinalis

2021 ◽  
Vol 170 ◽  
pp. 113730
Author(s):  
Alessandra Marchica ◽  
Roberta Ascrizzi ◽  
Guido Flamini ◽  
Lorenzo Cotrozzi ◽  
Mariagrazia Tonelli ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Salvia Officinalis ◽  
Bioactive Properties

Effect of phosphorus uptake on growth and secondary metabolites of garden sage (Salvia officinalis L.)

2009 ◽  
Vol 89 (6) ◽  
pp. 1090-1096 ◽  
Author(s):  
Monika Nell ◽  
Marlies Vötsch ◽  
Horst Vierheilig ◽  
Siegrid Steinkellner ◽  
Karin Zitterl-Eglseer ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Phosphorus Uptake ◽  
Salvia Officinalis ◽  
Salvia Officinalis L

scholarly journals Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona

Marine Drugs ◽  
2019 ◽  
Vol 17 (12) ◽  
pp. 682 ◽  
Author(s):  
Jiaying Zhu ◽  
Yang Liu ◽  
Zijun Liu ◽  
Hao Wang ◽  
Huawei Zhang
Keyword(s):  
Natural Products ◽  
Drug Discovery ◽  
Secondary Metabolites ◽  
Marine Sponge ◽  
Literature Search ◽  
Extensive Literature ◽  
Symbiotic Microorganisms ◽  
Bioactive Properties ◽  
Potential Applications ◽  
Extensive Literature Search

Marine sponge genus Haliclona, one of the most prolific sources of natural products, contains over 600 species but only a small part of them had been classified and chemically investigated. On the basis of extensive literature search, this review firstly summarizes 112 nitrogenous secondary metabolites from classified and unclassified Haliclona sponges as well as from their symbiotic microorganisms. Most of these substances have only been found in Haliclona sponges, and display diverse bioactive properties with potential applications in new drug discovery.

Origins, Structures, and Bioactivities of Secondary Metabolites from Marine-derived Penicillium Fungi

2021 ◽  
Vol 21 ◽  
Author(s):  
Xiliang Yang ◽  
Jinping Liu ◽  
Jiahui Mei ◽  
Rui Jiang ◽  
Shizheng Tu ◽  
...  
Keyword(s):  
Natural Products ◽  
Secondary Metabolites ◽  
Drug Development ◽  
Valuable Source ◽  
Chemical Structures ◽  
New Drug ◽  
Bioactive Properties ◽  
Potential Applications ◽  
New Drug Development ◽  
Anti Inflammatory

: In recent years, marine-derived Penicillium fungi have received remarkable interest as a valuable source of novel natural products encompassing diverse chemical structures and bioactive properties. Mangroves, sediments, algae, and sponges are the four main sources of marine-derived Penicillium fungi. As of 2014, more than 390 novel natural products have been isolated from the marine-derived Penicillium fungi, mainly including polyketides, alkaloids, terpenoids, and macrolides. Biological investigations have shown that these compounds possess antimicrobial, anti-inflammatory, cytotoxic, and other activities with potential applications in new drug development. To provide an updated catalog of this field, our mini-review summarized the origins, structures, and bioactivities of 188 secondary metabolites from marine-derived Penicillium fungi based on bioactivities classification published from 2015 to 2020.

scholarly journals Radiation-induced modification of secondary metabolites contents in plants of Salvia officinalis L. and Silybum marianum L.

2020 ◽  
Vol 26 ◽  
pp. 144-148
Author(s):  
S. A. Pchelovska ◽  
S. V. Litvinov ◽  
Yu. V. Shylina ◽  
V. V. Zhuk ◽  
K. V. Lystvan ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Raw Materials ◽  
Spectrophotometric Analysis ◽  
Salvia Officinalis ◽  
Physiological Status ◽  
Silybum Marianum ◽  
Radiation Technology ◽  
X Ray ◽  
Radiation Induced ◽  
Salvia Officinalis L

Aim. Long-term studies of the effect of sublethal doses of pre-sowing low-LET ionizing radiation on seeds have demonstrated the effectiveness of radiation biotechnology to stimulate the accumulation of pharmaceutically valuable secondary metabolites in medicinal raw materials of a number of common medicinal plants in Ukraine. The aim of this research was to evaluate the effectiveness of radiation technology in the case of seeds of Salvia officinalis L. and Silybum marianum L. Methods. X-ray irradiation of seeds at doses up to 50 Gy, spectrophotometric analysis of water-ethanol extracts, fluorescence microscopy of leaf epidermis were used. Results. Doses of pre-sowing X-ray irradiation were selected which maximally stimulate both the increase of biomass of medicinal raw materials and the accumulation of secondary metabolites. In particular for Salvia officinalis L. doses are 5 Gy and 20 Gy, for Silybum marianum L. are 10 Gy and 20 Gy. Conclusions. It is recommended to use two stimulating doses at the same time, as the result of exposure depends essentially on the physiological status of the seeds, growing conditions, varietal characteristics. Increasing the content of flavonoids and phenols in medicinal raw materials has been shown to be a reliable and reproducible marker of stimulating of rosemary acid accumulation in Salvia officinalis leaves. Keywords: radiation-induced stimulation, Salvia officinalis, Silybum marianum, rosemary acid, silibinin.

scholarly journals Evaluation of bioactive properties and phenolic compounds in different extracts prepared from Salvia officinalis L.

2015 ◽  
Vol 170 ◽  
pp. 378-385 ◽  
Author(s):  
Natália Martins ◽  
Lillian Barros ◽  
Celestino Santos-Buelga ◽  
Mariana Henriques ◽  
Sónia Silva ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Salvia Officinalis ◽  
Bioactive Properties ◽  
Salvia Officinalis L

scholarly journals Effects of growth conditions and cultivability on the content of cyclitols in Medicago sativa

2020 ◽  
Author(s):  
I. A. Ratiu ◽  
H. Al-Suod ◽  
M. Ligor ◽  
F. Monedeiro ◽  
B. Buszewski
Keyword(s):  
Secondary Metabolites ◽  
Medicago Sativa ◽  
Abiotic Factors ◽  
Growth Conditions ◽  
Alfalfa Plant ◽  
Naturally Occurring ◽  
Bioactive Properties ◽  
Seasonal Impact ◽  
Low Humidity ◽  
Plant Treatment

Abstract Cyclitols are secondary metabolites with bioactive properties, naturally occurring in plants. Accumulation of such metabolites is directly connected with abiotic stressing factors. This article investigates the influence exercised by a series of abiotic factors including plant treatment with elicitors and cultivability in various regions of Europe, in some cases during two seasons, onto the amounts of cyclitols produced in alfalfa (Medicago sativa L.). The obtained results highlighted that NaCl elicitation acts to increase the quantity of cyclitols, while AgNO3 and Zn(NO3)2 generally decreased the obtained amount of cyclitols. When considering the seasonal impact, samples harvested in August presented a double amount of cyclitols in comparison with those collected in May. Correlation analysis proved that this phenomenon is related mainly to sunshine period versus low humidity. However, our investigation suggests that soil type, salinity level, lack of humidity, the number of sunny days, and plant elicitation play a role on the amount of cyclitols produced in alfalfa plant.

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