Role of plant biotechnology in enhancement of alkaloid production from cell culture system of Catharanthus roseus: A medicinal plant with potent anti-tumor properties

2022 ◽  
Vol 176 ◽  
pp. 114298
Author(s):  
Santoshi Acharjee ◽  
Raghawendra Kumar ◽  
Nitish Kumar
2005 ◽  
Vol 332 (4) ◽  
pp. 1162-1170 ◽  
Author(s):  
Daniela G. Seidler ◽  
Liliana Schaefer ◽  
Horst Robenek ◽  
Renato V. Iozzo ◽  
Hans Kresse ◽  
...  

2020 ◽  
Vol 45 (5) ◽  
pp. 631-637
Author(s):  
Cansu Ozel-Tasci ◽  
Gozde Pilatin ◽  
Ozgur Edeer ◽  
Sukru Gulec

AbstractBackgroundFunctional foods can help prevent metabolic diseases, and it is essential to evaluate functional characteristics of foods through in vitro and in vivo experimental approaches.ObjectiveWe aimed to use the bicameral cell culture system combined with the in vitro digestion to evaluate glucose bioavailability.Materials and methodsCake, almond paste, and pudding were modified by adding fiber and replacing sugar with sweeteners and polyols. Digestion process was modeled in test tubes. Rat enterocyte cells (IEC-6) were grown in a bicameral cell culture system to mimic the physiological characteristics of the human intestine. The glucose bioaccessibility and cellular glucose efflux were measured by glucose oxidase assay.Results and discussionThe glucose bioaccessibilities of modified foods were significantly lower (cake: 2.6 fold, almond paste: 9.2 fold, pudding 2.8 fold) than the controls. Cellular glucose effluxes also decreased in the modified cake, almond paste, and pudding by 2.2, 4, and 2 fold respectively compared to their controls.ConclusionOur results suggest that combining in vitro enzymatic digestion with cell culture studies can be a practical way to test in vitro glucose bioaccessibility and bioavailability in functional food development.


2018 ◽  
Vol 257 ◽  
pp. 650-657 ◽  
Author(s):  
Azadeh Nilghaz ◽  
Siew Hoo ◽  
Wei Shen ◽  
Xiaonan Lu ◽  
Peggy P.Y. Chan

2015 ◽  
Vol 120 ◽  
pp. 279-285 ◽  
Author(s):  
Sabine Schnell ◽  
Kafilat Bawa-Allah ◽  
Adebayo Otitoloju ◽  
Christer Hogstrand ◽  
Thomas H. Miller ◽  
...  

2000 ◽  
Author(s):  
Masato Sato ◽  
Miya Ishihara ◽  
Tsunenori Arai ◽  
Takashi Asazuma ◽  
Toshiyuki Kikuchi ◽  
...  

1995 ◽  
Vol 42 (2) ◽  
pp. 150-157 ◽  
Author(s):  
LOUIS M. WEISS ◽  
DENISE LAPLACE ◽  
PETER M. TAKVORIAN ◽  
HERBERT B. TANOWITZ ◽  
ANN CALI ◽  
...  

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