Electrophoretic deposition of biphasic calcium phosphate/graphene nanocomposite coatings on Ti6Al4V substrate for biomedical applications

2022 ◽  
Vol 892 ◽  
pp. 162150
Author(s):  
Safoora Farshid ◽  
Mehdi Ebrahimian-Hosseinabadi ◽  
Mohammad Rafienia
2010 ◽  
Vol 12 (6) ◽  
pp. B192-B199 ◽  
Author(s):  
Hicham Benhayoune ◽  
Richard Drevet ◽  
Joel Fauré ◽  
Sylvain Potiron ◽  
Thierry Gloriant ◽  
...  

2021 ◽  
Vol 11 (8) ◽  
pp. 1428-1437
Author(s):  
Ping Sun ◽  
Shuyi Li ◽  
Jianhua Niu ◽  
Min Yi ◽  
Weixing Xu ◽  
...  

A biphasic calcium-phosphate (CaP)-coating is a promising surface modification for functionalizing various endosseous biomaterials. However, its biomedical application is limited by its low coating yield and incorporation inefficiency. We developed a highly concentrated (4.5×) supersaturated calcium-phosphate solution (SCPS) and compared its physicochemical properties with those of 1× SCPS. One milliliter of 4.5× SCPS formed a thick (110 μm) continuous coating on a titanium disc (4×4×1 mm), compared to the thin (29 μm) 1× SCPScoating. On X-ray diffraction analysis, the 4.5× SCPS-coating had characteristic dicalcium-phosphate dehydrate and apatite peaks, in contrast to the apatite-only of 1× SCPS-coating. Under acidic condition (pH 4.5), the 4. × 5SCPS-coating released significantly less Ca2+ than the 1× SCPS-coating. FITC-bovine serum albumin incorporation in the 4.5× SCPS-coating (81.20±6.42%) was significantly higher than in the 1× SCPS-coating (21.86±1.90%). Thus, this modified coating procedure holds promise for biomedical applications.


2019 ◽  
Vol 16 (5) ◽  
pp. 1932-1943
Author(s):  
Vidhya Ganesan ◽  
Muthu Devaraj ◽  
Suresh Kumar Govindan ◽  
Vivekanand S. Kattimani ◽  
Girija Easwaradas Kreedapathy

2012 ◽  
Vol 506 ◽  
pp. 74-77 ◽  
Author(s):  
Naruporn Monmaturapoj ◽  
Witoon Thepsuwan

Biphasic calcium phosphate (BCP) ceramic is commonly used in the biomedical applications particularly as a bone substitute due to its biocompatibility and directly bond to bones. However, the mechanical strength is quite poor. Therefore, well known biocompatible and strong ceramics such as SiO2, ZrO2 and TiO2 were added to improve the strength of BCP. BCP powder with HA/TCP ratios of 70/30 (HAP7030) was obtained by controlling the calcining temperature of the mixture between a pure HA and TCP. SiO2, ZrO2 and TiO2 powder with 2, 5 and 10 %wt were mixed with the HAP7030 powder by ball milling in ethanol. The mixtures were dried, pressed and sintered at 1100°C for 2 hrs. XRD and SEM were used to determine crystal structures and morphology of the sintered samples, respectively. Physical properties and flexural strength of samples were measured. Results showed that the bending strength of HAP7030 sample was rather improved by adding TiO2 than the addition of SiO2 or ZrO2. With increasing TiO2, HAP7030 strength was superior and HAP7030 with 10 %wt of TiO2 obtained the optimum bending strength around 61 MPa. However, the addition of TiO2 induced the thermal stability of HA/TCP, in which HA completely decomposed to β-TCP in this study.


2012 ◽  
Vol 620 ◽  
pp. 373-377 ◽  
Author(s):  
Asam M.A. Abudalazez ◽  
Shah Rizal Kasim ◽  
Azlan B. Ariffin ◽  
Zainal Arifin Ahmad

Biphasic calcium phosphate (BCP) ceramic is a synthetic biomaterial exhibiting a chemical composition similar to that of tooth mineral. Therefore, it is viably used in coating metallic implants manufactured from metals and alloys, such as titanium and stainless steel. In the present study, electrophoretic deposition (EPD) has been attempted for depositing BCP coatings on 316L Stainless Steel substrate followed by vacuum sintering at 800 °C for 1 h. The surface morphology, thickness, compositions and microstructure of the BCP coated 316L SS was investigated by scanning electron microscope (SEM), energy dispersive spectrometer (EDS), X-ray diffraction (XRD) and the bond strength of the coating was measured.


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