Interspecies comparison of plasma metabolism and sample stabilization for quantitative bioanalyses: application to (R)-CE3F4 in preclinical development, including metabolite identification by high-resolution mass spectrometry

Journal of Chromatography B ◽

10.1016/j.jchromb.2021.122943 ◽

2021 ◽

pp. 122943

Author(s):

Balthazar Toussaint ◽

Hervé Hillaireau ◽

Emmanuel Jaccoulet ◽

Catherine Cailleau ◽

Pauline Legrand ◽

...

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

High Resolution Mass Spectrometry ◽

Metabolite Identification ◽

Preclinical Development ◽

Interspecies Comparison ◽

High Resolution Mass ◽

Resolution Mass

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4-Methoxy-α-PVP: in silico prediction, metabolic stability, and metabolite identification by human hepatocyte incubation and high-resolution mass spectrometry

Forensic Toxicology ◽

10.1007/s11419-015-0287-4 ◽

2015 ◽

Vol 34 (1) ◽

pp. 61-75 ◽

Cited By ~ 29

Author(s):

Kayla N. Ellefsen ◽

Ariane Wohlfarth ◽

Madeleine J. Swortwood ◽

Xingxing Diao ◽

Marta Concheiro ◽

...

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

In Silico ◽

High Resolution Mass Spectrometry ◽

Metabolite Identification ◽

Human Hepatocyte ◽

Metabolic Stability ◽

In Silico Prediction ◽

High Resolution Mass ◽

Resolution Mass

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Metabolite identification and profile of endosulfan sulfate in three human liver preparations using liquid chromatography-high resolution mass spectrometry

Journal of Chromatography B ◽

10.1016/j.jchromb.2020.121996 ◽

2020 ◽

Vol 1140 ◽

pp. 121996

Author(s):

Hwa-Kyung Lee ◽

Tae Yeon Kong ◽

Won-Gu Choi ◽

Ju-Hyun Kim ◽

Yongho Shin ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

High Resolution ◽

Human Liver ◽

High Resolution Mass Spectrometry ◽

Metabolite Identification ◽

Endosulfan Sulfate ◽

High Resolution Mass ◽

Resolution Mass

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Update on metabolism of abemaciclib: In silico , in vitro , and in vivo metabolite identification and characterization using high resolution mass spectrometry

Drug Testing and Analysis ◽

10.1002/dta.2725 ◽

2020 ◽

Vol 12 (3) ◽

pp. 331-342 ◽

Cited By ~ 2

Author(s):

Disha Thakkar ◽

Abhijeet S. Kate

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

In Silico ◽

High Resolution Mass Spectrometry ◽

Metabolite Identification ◽

High Resolution Mass ◽

Identification And Characterization ◽

Resolution Mass

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Mass defect filter technique and its applications to drug metabolite identification by high-resolution mass spectrometry

Journal of Mass Spectrometry ◽

10.1002/jms.1610 ◽

2009 ◽

Vol 44 (7) ◽

pp. 999-1016 ◽

Cited By ~ 183

Author(s):

Haiying Zhang ◽

Donglu Zhang ◽

Kenneth Ray ◽

Mingshe Zhu

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

High Resolution Mass Spectrometry ◽

Metabolite Identification ◽

Mass Defect ◽

Filter Technique ◽

Drug Metabolite ◽

High Resolution Mass ◽

Mass Defect Filter ◽

Resolution Mass

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Development of a Liquid Chromatography–High Resolution Mass Spectrometry Metabolomics Method with High Specificity for Metabolite Identification Using All Ion Fragmentation Acquisition

Analytical Chemistry ◽

10.1021/acs.analchem.7b00925 ◽

2017 ◽

Vol 89 (15) ◽

pp. 7933-7942 ◽

Cited By ~ 54

Author(s):

Shama Naz ◽

Hector Gallart-Ayala ◽

Stacey N. Reinke ◽

Caroline Mathon ◽

Richard Blankley ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

High Resolution ◽

High Resolution Mass Spectrometry ◽

Metabolite Identification ◽

High Specificity ◽

Ion Fragmentation ◽

High Resolution Mass ◽

Resolution Mass

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High-Resolution Mass Spectrometry in Metabolite Identification

Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis - Comprehensive Analytical Chemistry ◽

10.1016/bs.coac.2016.01.004 ◽

2016 ◽

pp. 199-229 ◽

Cited By ~ 2

Author(s):

M.K. Ladumor ◽

S. Tiwari ◽

A. Patil ◽

K. Bhavsar ◽

S. Jhajra ◽

...

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

High Resolution Mass Spectrometry ◽

Metabolite Identification ◽

High Resolution Mass ◽

Resolution Mass

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Understanding the magnitude of emergent contaminant releases through target screening and metabolite identification using high resolution mass spectrometry: Illicit drugs in raw sewage influents

Journal of Hazardous Materials ◽

10.1016/j.jhazmat.2014.08.009 ◽

2015 ◽

Vol 282 ◽

pp. 41-50 ◽

Cited By ~ 17

Author(s):

Nubia V. Heuett ◽

Sudha Rani Batchu ◽

Piero R. Gardinali

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

Illicit Drugs ◽

High Resolution Mass Spectrometry ◽

Metabolite Identification ◽

High Resolution Mass ◽

Target Screening ◽

Resolution Mass

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Metabolite identification of the antimalarial naphthoquine using liquid chromatography-tandem high-resolution mass spectrometry in combination with multiple data-mining tools

Biomedical Chromatography ◽

10.1002/bmc.4207 ◽

2018 ◽

Vol 32 (6) ◽

pp. e4207 ◽

Cited By ~ 3

Author(s):

Yanhong Sun ◽

Shuqi Wang ◽

Jianbo Ji ◽

Guangxi Zhai ◽

Jie Xing

Keyword(s):

Mass Spectrometry ◽

Data Mining ◽

Liquid Chromatography ◽

High Resolution ◽

High Resolution Mass Spectrometry ◽

Metabolite Identification ◽

High Resolution Mass ◽

Multiple Data ◽

Mining Tools ◽

Resolution Mass

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Drug Metabolite Identification with High-resolution Mass Spectrometry

Handbook of Metabolic Pathways of Xenobiotics ◽

10.1002/9781118541203.xen0025 ◽

2014 ◽

pp. 1-23 ◽

Cited By ~ 1

Author(s):

Haiying Zhang ◽

Mingshe Zhu

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

High Resolution Mass Spectrometry ◽

Metabolite Identification ◽

Drug Metabolite ◽

High Resolution Mass ◽

Resolution Mass

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Metabolite identification of the antimalarial piperaquinein vivousing liquid chromatography-high-resolution mass spectrometry in combination with multiple data-mining tools in tandem

Biomedical Chromatography ◽

10.1002/bmc.3689 ◽

2016 ◽

Vol 30 (8) ◽

pp. 1324-1330 ◽

Cited By ~ 7

Author(s):

Aijuan Yang ◽

Meitong Zang ◽

Huixiang Liu ◽

Peihong Fan ◽

Jie Xing

Keyword(s):

Mass Spectrometry ◽

Data Mining ◽

Liquid Chromatography ◽

High Resolution ◽

High Resolution Mass Spectrometry ◽

Metabolite Identification ◽

High Resolution Mass ◽

Multiple Data ◽

Mining Tools ◽

Resolution Mass

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