scholarly journals Modulating in vitro release and solubility of griseofulvin using functionalized mesoporous silica nanoparticles

2014 ◽  
Vol 434 ◽  
pp. 218-225 ◽  
Author(s):  
Siddharth Jambhrunkar ◽  
Zhi Qu ◽  
Amirali Popat ◽  
Surajit Karmakar ◽  
Chun Xu ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
In Vitro Release ◽  
Functionalized Mesoporous Silica ◽  
Vitro Release

scholarly journals Indometacin loading and in vitro release properties from novel carbopol coated spherical mesoporous silica nanoparticles

2013 ◽  
Vol 171 ◽  
pp. 131-138 ◽  
Author(s):  
Borislav Tzankov ◽  
Krassimira Yoncheva ◽  
Margarita Popova ◽  
Agnes Szegedi ◽  
Georgi Momekov ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
In Vitro Release ◽  
Vitro Release

scholarly journals pH Responsive in Vitro Cargo Release of PEG Coated MSNs Is Governed by Buffer Composition

2020 ◽  
Author(s):  
Nidhi Sapre ◽  
Gaurav Das ◽  
Sneha Bajpe
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Standard Procedure ◽  
In Vitro Release ◽  
Citrate Buffer ◽  
Buffer Composition ◽  
The Right ◽  
Vitro Release

<p>The effect of different buffers on in vitro release of PEG coated mesoporous silica nanoparticles is discussed in this work. We prepared Rhodamine loaded and PEG coated mesoporous silica nanoparticles (PEG coated RhB@MSNs) of ~ 650 nm size and studied their release behaviour for 5 hours in various buffer solutions (both Na+ and K+ versions) prepared by standard procedure. We observed that Rhodamine release was highest in the citrate buffer. A comparison of different buffer effects on the in vitro release reveals that it is crucial to choose the right buffer for determining the loaded cargo release in each pH zone (acidic, neutral and basic). Clearly, choosing the wrong combination of buffers for different pH zones would result in completely different interpretation of the release behaviour.</p><div><br></div>

scholarly journals pH Responsive in Vitro Cargo Release of PEG Coated MSNs Is Governed by Buffer Composition

2020 ◽  
Author(s):  
Nidhi Sapre ◽  
Gaurav Das ◽  
Sneha Bajpe
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Standard Procedure ◽  
In Vitro Release ◽  
Citrate Buffer ◽  
Buffer Composition ◽  
The Right ◽  
Vitro Release

<p>The effect of different buffers on in vitro release of PEG coated mesoporous silica nanoparticles is discussed in this work. We prepared Rhodamine loaded and PEG coated mesoporous silica nanoparticles (PEG coated RhB@MSNs) of ~ 650 nm size and studied their release behaviour for 5 hours in various buffer solutions (both Na+ and K+ versions) prepared by standard procedure. We observed that Rhodamine release was highest in the citrate buffer. A comparison of different buffer effects on the in vitro release reveals that it is crucial to choose the right buffer for determining the loaded cargo release in each pH zone (acidic, neutral and basic). Clearly, choosing the wrong combination of buffers for different pH zones would result in completely different interpretation of the release behaviour.</p><div><br></div>

scholarly journals In vitro speciation of molybdenum in human biological samples based on thiol functionalized mesoporous silica nanoparticles and hexyl-methylimidazolium tris-pentafluoroethyl-trifluorophosphate

2020 ◽  
Vol 3 (03) ◽  
pp. 54-64
Author(s):  
Roya Ashori ◽  
Seyed Alireza Hajiseyed Mirzahosseini
Keyword(s):  
Ionic Liquid ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Biological Samples ◽  
Solid Phase ◽  
Mesoporous Silica Nanoparticles ◽  
Electrothermal Atomic Absorption Spectrometry ◽  
Serum Samples ◽  
Functionalized Mesoporous Silica

Molybdenum (Mo) ions enter to human body from the diet or drinking waters and have a potentially toxic effect on humans. The thiol-functionalized mesoporous silica nanoparticles (HS-MSNPs) were used for determination and speciation of Mo (II, VI) in human biological samples by dispersive ionic liquid-micro-solid phase extraction (DIL-μ-SPE) coupled to electrothermal atomic absorption spectrometry (ET-AAS). Firstly, the mixture of HS-MSNPs (15 mg), the hydrophobic ionic liquid (1-Hexyl-3-methylimidazolium tris(pentafluoroethyl) trifluorophosphate; [HMIM][T(PFE)PF3]) and acetone injected into 10 mL of human blood and serum samples. After shaking for 5 min, the Mo(II) and Mo(VI) ions were extracted with the thiol group of MSNPs at pH 6 and 2, respectively, and collected through IL at the bottom of the conical tube by centrifuging. Then, the MO(II,VI) ions were back-extracted from HS-MSNPs with elent based on changing pH, and remained solutions were determined by ET-AAS after dilution with DW up to 0.5 mL, separately.

scholarly journals In vitro Studies of Functionalized Mesoporous Silica Nanoparticles for Photodynamic Therapy

2009 ◽  
Vol 21 (2) ◽  
pp. 172-177 ◽  
Author(s):  
Hsiung-Lin Tu ◽  
Yu-Shen Lin ◽  
Hsia-Yu Lin ◽  
Yann Hung ◽  
Leu-Wei Lo ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
In Vitro Studies ◽  
Functionalized Mesoporous Silica
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